Cardiovascular Disease Risk Stratification Using Hybrid Deep Learning Paradigm: First of Its Kind on Canadian Trial Data.

and stability cardiovascular disease risk hybrid deep learning machine learning feature extraction performance evaluation reliability scientific validation

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
28 Aug 2024
Historique:
received: 10 07 2024
revised: 12 08 2024
accepted: 26 08 2024
medline: 14 9 2024
pubmed: 14 9 2024
entrez: 14 9 2024
Statut: epublish

Résumé

The risk of cardiovascular disease (CVD) has traditionally been predicted via the assessment of carotid plaques. In the proposed study, AtheroEdge™ 3.0 500 people who had undergone targeted carotid B-mode ultrasonography and coronary angiography were included in the proposed study. ML feature selection was carried out using three different methods, namely principal component analysis (PCA) pooling, the chi-square test (CST), and the random forest regression (RFR) test. The unidirectional and bidirectional deep learning models were trained, and then six types of novel HDL-based models were designed for CVD risk stratification. The AtheroEdge™ 3.0 The HDL system showed an improvement of 30.20% (0.954 vs. 0.702) over the ML system using the The hypothesis for AtheroEdge™ 3.0

Sections du résumé

BACKGROUND BACKGROUND
The risk of cardiovascular disease (CVD) has traditionally been predicted via the assessment of carotid plaques. In the proposed study, AtheroEdge™ 3.0
METHODOLOGY METHODS
500 people who had undergone targeted carotid B-mode ultrasonography and coronary angiography were included in the proposed study. ML feature selection was carried out using three different methods, namely principal component analysis (PCA) pooling, the chi-square test (CST), and the random forest regression (RFR) test. The unidirectional and bidirectional deep learning models were trained, and then six types of novel HDL-based models were designed for CVD risk stratification. The AtheroEdge™ 3.0
RESULTS RESULTS
The HDL system showed an improvement of 30.20% (0.954 vs. 0.702) over the ML system using the
CONCLUSIONS CONCLUSIONS
The hypothesis for AtheroEdge™ 3.0

Identifiants

pubmed: 39272680
pii: diagnostics14171894
doi: 10.3390/diagnostics14171894
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Mrinalini Bhagawati (M)

Department of Biomedical Engineering, North-Eastern Hill University, Shillong 793022, India.

Sudip Paul (S)

Department of Biomedical Engineering, North-Eastern Hill University, Shillong 793022, India.

Laura Mantella (L)

Division of Cardiology, Department of Medicine, University of Toronto, Toronto, ON M5S 1A1, Canada.

Amer M Johri (AM)

Division of Cardiology, Department of Medicine, Queen's University, Kingston, ON K7L 3N6, Canada.

Siddharth Gupta (S)

Department of Computer Science and Engineering, Bharati Vidyapeeth's College of Engineering, New Delhi 110063, India.

John R Laird (JR)

Heart and Vascular Institute, Adventist Health St. Helena, St. Helena, CA 94574, USA.

Inder M Singh (IM)

Stroke Diagnostic and Monitoring Division, AtheroPoint™, Roseville, CA 95661, USA.

Narendra N Khanna (NN)

Cardiology Department, Apollo Hospitals, New Delhi 110076, India.

Mustafa Al-Maini (M)

Allergy, Clinical Immunology and Rheumatology Institute, Toronto, ON M5G 1N8, Canada.

Esma R Isenovic (ER)

Department of Radiobiology and Molecular Genetics, National Institute of The Republic of Serbia, University of Belgrade, 11001 Belgrade, Serbia.

Ekta Tiwari (E)

Department of Computer Science, Visvesvaraya National Institute of Technology (VNIT), Nagpur 440010, India.

Rajesh Singh (R)

Division of Research and Innovation, UTI, Uttaranchal University, Dehradun 248007, India.

Andrew Nicolaides (A)

Vascular Screening and Diagnostic Centre, University of Nicosia, Nicosia 2417, Cyprus.

Luca Saba (L)

Department of Radiology, Azienda Ospedaliero Universitaria, 40138 Cagliari, Italy.

Vinod Anand (V)

Stroke Diagnostic and Monitoring Division, AtheroPoint™, Roseville, CA 95661, USA.

Jasjit S Suri (JS)

Stroke Diagnostic and Monitoring Division, AtheroPoint™, Roseville, CA 95661, USA.
Department of CE, Graphic Era Deemed to be University, Dehradun 248002, India.
Department of ECE, Idaho State University, Pocatello, ID 83209, USA.
University Center for Research & Development, Chandigarh University, Mohali 140413, India.
Symbiosis Institute of Technology, Nagpur Campus, Symbiosis International (Deemed University), Pune 412115, India.

Classifications MeSH