Conjugation of CRAMP

Chitosan / chemistry Anti-Bacterial Agents / pharmacology Copper / chemistry Cycloaddition Reaction Azides / chemistry Catalysis Alkynes / chemistry Microbial Sensitivity Tests Antimicrobial Cationic Peptides / chemistry Cathelicidins Animals Staphylococcus aureus / drug effects Mice Enterococcus faecalis / drug effects
antibacterial activity antimicrobial peptide chitosan click chemistry

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
30 Aug 2024
Historique:
received: 14 07 2024
revised: 22 08 2024
accepted: 27 08 2024
medline: 14 9 2024
pubmed: 14 9 2024
entrez: 14 9 2024
Statut: epublish

Résumé

We developed a synthesis strategy involving a diazo transfer reaction and subsequent click reaction to conjugate a murine cathelicidin-related antimicrobial peptide (CRAMP

Identifiants

DOI: 10.3390/ijms25179440 PMID: 39273387
pubmed: 39273387
pii: ijms25179440
doi: 10.3390/ijms25179440
pii:
doi:

Substances chimiques

Chitosan 9012-76-4
Anti-Bacterial Agents 0
Copper 789U1901C5
Azides 0
Alkynes 0
Antimicrobial Cationic Peptides 0
Cathelicidins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : The Icelandic Research Fund
ID : 1709-0210
Organisme : doctoral grant from the University of Iceland Research Fund
ID : 00

Auteurs

Sankar Rathinam (S)

Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, Hofsvallagata 53, IS-107 Reykjavík, Iceland.
ORCID: 0000-0003-0193-6532

Kasper K Sørensen (KK)

Department of Chemistry, Faculty of Science, University of Copenhagen, Thorvaldsensvej 40, DK-1871 Frederiksberg C, Denmark.

Martha Á Hjálmarsdóttir (MÁ)

Department of Biomedical Science, Faculty of Medicine, School of Health Sciences, University of Iceland, Hringbraut 31, IS-101 Reykjavík, Iceland.

Mikkel B Thygesen (MB)

Department of Chemistry, Faculty of Science, University of Copenhagen, Thorvaldsensvej 40, DK-1871 Frederiksberg C, Denmark.
ORCID: 0000-0002-0158-2802

Már Másson (M)

Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, Hofsvallagata 53, IS-107 Reykjavík, Iceland.
ORCID: 0000-0003-0363-3316

Articles similaires

Vancomycin-associated DRESS demonstrates delay in AST abnormalities.

Ahmed Hussein, Kateri L Schoettinger, Jourdan Hydol-Smith et al.
1.00
Humans Drug Hypersensitivity Syndrome Vancomycin Female Male

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Classifications MeSH

questionsmedicales.fr › Glucides › Polyosides › Chitine › Chitosane › Conjugation of CRAMP
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Conjugation of CRAMP
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Cuivre › Conjugation of CRAMP
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Technologie pharmaceutique › Techniques de chimie synthétique › Réaction de cycloaddition › Conjugation of CRAMP
questionsmedicales.fr › Composés chimiques organiques › Azotures › Conjugation of CRAMP
questionsmedicales.fr › Phénomènes chimiques › Catalyse › Conjugation of CRAMP
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures acycliques › Alcynes › Conjugation of CRAMP
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Conjugation of CRAMP
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Perforines › Peptides antimicrobiens cationiques › Conjugation of CRAMP
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Perforines › Peptides antimicrobiens cationiques › Cathélicidines › Conjugation of CRAMP
questionsmedicales.fr › Eucaryotes › Animaux › Conjugation of CRAMP
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Conjugation of CRAMP
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Conjugation of CRAMP
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Lactobacillales › Enterococcaceae › Enterococcus › Enterococcus faecalis › Conjugation of CRAMP