Cyclodextrin Complexes for the Treatment of Chagas Disease: A Literature Review.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
01 Sep 2024
Historique:
received: 10 07 2024
revised: 25 08 2024
accepted: 27 08 2024
medline: 14 9 2024
pubmed: 14 9 2024
entrez: 14 9 2024
Statut: epublish

Résumé

Cyclodextrins are ring-shaped sugars used as additives in medications to improve solubility, stability, and sensory characteristics. Despite being widespread, Chagas disease is neglected because of the limitations of available medications. This study aims to review the compounds used in the formation of inclusion complexes for the treatment of Chagas disease, analyzing the incorporated compounds and advancements in related studies. The databases consulted include Scielo, Scopus, ScienceDirect, PubMed, LILACS, and Embase. The keywords used were "cyclodextrin AND Chagas AND disease" and "cyclodextrin complex against

Identifiants

pubmed: 39273458
pii: ijms25179511
doi: 10.3390/ijms25179511
pii:
doi:

Substances chimiques

Cyclodextrins 0
Trypanocidal Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Fabrice Taio (F)

Department of Pharmacy, Health Sciences Center, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil.

Attilio Converti (A)

Department of Civil, Chemical and Environmental Engineering, Pole of Chemical Engineering, Genoa University, I-16145 Genoa, Italy.

Ádley Antonini Neves de Lima (ÁAN)

Department of Pharmacy, Health Sciences Center, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil.

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Classifications MeSH