Levels of B-ALP and TRAP-5b in a patient with short root anomaly: a case report.
Clinical examination
Laboratory test
Osteoblast
Osteoclast
Short root anomaly
Journal
The Journal of clinical pediatric dentistry
ISSN: 1557-5268
Titre abrégé: J Clin Pediatr Dent
Pays: Singapore
ID NLM: 9100079
Informations de publication
Date de publication:
Sep 2024
Sep 2024
Historique:
received:
13
12
2022
accepted:
06
01
2023
medline:
14
9
2024
pubmed:
14
9
2024
entrez:
14
9
2024
Statut:
ppublish
Résumé
The purpose of this study was to observe the changes in bone-specific alkaline phosphatase (B-ALP) and tartrate-resistant acid phosphatase-5b (TRAP-5b) in a patient diagnosed with short root anomaly (SRA). The detailed clinical data and history of related clinical symptoms of the SRA patient were retrieved. Oral examination showed that the shape and color of the tooth crown were normal. Tooth 11 and 12 were missing, and the mobility degree of other teeth was II-III. Panoramic radiograph examination showed that the root length only reached the neck of the tooth. Laboratory results showed that blood spectrum, chromosome and trace elements were normal. Endocrinological evaluation indicated that hormone levels were within normal limits; however, both B-ALP and TRAP-5b were higher than the normal range. The present case shows that SRA may be related to an imbalance in osteoblast/osteoclast metabolism, which provides a new direction for the etiological research of this disease.
Identifiants
pubmed: 39275837
pii: S1053-4628(24)00202-9
doi: 10.22514/jocpd.2024.119
doi:
Substances chimiques
Alkaline Phosphatase
EC 3.1.3.1
Tartrate-Resistant Acid Phosphatase
EC 3.1.3.2
ACP5 protein, human
EC 3.1.3.2
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
189-192Informations de copyright
©2024 The Author(s). Published by MRE Press.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.