Variational Bayes machine learning for risk adjustment of general outcome indicators with examples in urology.


Journal

NPJ digital medicine
ISSN: 2398-6352
Titre abrégé: NPJ Digit Med
Pays: England
ID NLM: 101731738

Informations de publication

Date de publication:
14 Sep 2024
Historique:
received: 03 11 2023
accepted: 01 09 2024
medline: 15 9 2024
pubmed: 15 9 2024
entrez: 14 9 2024
Statut: epublish

Résumé

Risk adjustment is often necessary for outcome quality indicators (QIs) to provide fair and accurate feedback to healthcare professionals. However, traditional risk adjustment models are generally oversimplified and not equipped to disentangle complex factors influencing outcomes that are out of a healthcare professional's control. We present VIRGO, a novel variational Bayes model trained on routinely collected, large administrative datasets to risk-adjust outcome QIs. VIRGO uses detailed demographics, diagnosis, and procedure codes to provide individualized risk adjustment and explanations on patient factors affecting outcomes. VIRGO achieves state-of-the-art on external datasets and features capabilities of uncertainty expression, explainable features, and counterfactual analysis capabilities. VIRGO facilitates risk adjustment by explaining how patient factors led to adverse outcomes and expresses the uncertainty of each prediction, allowing healthcare professionals to not only explore patient factors with unexplained variance that are associated with worse outcomes but also reflect on the quality of their clinical practice.

Identifiants

pubmed: 39277683
doi: 10.1038/s41746-024-01244-z
pii: 10.1038/s41746-024-01244-z
doi:

Types de publication

Journal Article

Langues

eng

Pagination

249

Informations de copyright

© 2024. The Author(s).

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Auteurs

Harvey Jia Wei Koh (HJW)

Centre for Learning Analytics, Faculty of Information Technology, Monash University, Clayton, VIC, Australia.
Digital Health Cooperative Research Centre, Sydney, NSW, Australia.
School of Public Health and Preventative Medicine, Monash University, Melbourne, VIC, Australia.

Dragan Gašević (D)

Centre for Learning Analytics, Faculty of Information Technology, Monash University, Clayton, VIC, Australia.
Digital Health Cooperative Research Centre, Sydney, NSW, Australia.

David Rankin (D)

Digital Health Cooperative Research Centre, Sydney, NSW, Australia.
School of Public Health and Preventative Medicine, Monash University, Melbourne, VIC, Australia.

Stephane Heritier (S)

School of Public Health and Preventative Medicine, Monash University, Melbourne, VIC, Australia.

Mark Frydenberg (M)

Cabrini Healthcare, Malvern, VIC, Australia.
Department of Surgery, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia.

Stella Talic (S)

Centre for Learning Analytics, Faculty of Information Technology, Monash University, Clayton, VIC, Australia. stella.talic@monash.edu.
Digital Health Cooperative Research Centre, Sydney, NSW, Australia. stella.talic@monash.edu.
School of Public Health and Preventative Medicine, Monash University, Melbourne, VIC, Australia. stella.talic@monash.edu.

Classifications MeSH