Effect of aflatoxin B1 and sterigmatocystin on DNA repair genes in common carp.
DNA repair
Gene expression
Mycotoxins
Sterigmatocystin
Journal
Aquatic toxicology (Amsterdam, Netherlands)
ISSN: 1879-1514
Titre abrégé: Aquat Toxicol
Pays: Netherlands
ID NLM: 8500246
Informations de publication
Date de publication:
02 Sep 2024
02 Sep 2024
Historique:
received:
12
07
2024
revised:
17
08
2024
accepted:
01
09
2024
medline:
16
9
2024
pubmed:
16
9
2024
entrez:
15
9
2024
Statut:
aheadofprint
Résumé
The present study aimed to investigate the short-time (24 h) effect of aflatoxin B1 (AFB1) and sterigmatocystin (STC) on the expression of hsp70, p53, gadd45, and ogg1 genes in common carp hepatopancreas. Our results showed that aflatoxin B1 and sterigmatocystin can stimulate the expression of DNA repair genes, mainly by hour 24. This significant finding contributes to our understanding of the short-term effects of these mycotoxins on ogg1 genes in common carp hepatopancreas. One-year-old common carp juveniles were randomly distributed into five groups (Control, AFB1 0.4 mg kg
Identifiants
pubmed: 39277992
pii: S0166-445X(24)00246-7
doi: 10.1016/j.aquatox.2024.107076
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
107076Informations de copyright
Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.