Metabolic engineering of rapidly growing Synechococcus elongatus strains for phototrophic production of alkanes.
Journal
Biotechnology progress
ISSN: 1520-6033
Titre abrégé: Biotechnol Prog
Pays: United States
ID NLM: 8506292
Informations de publication
Date de publication:
15 Sep 2024
15 Sep 2024
Historique:
revised:
18
08
2024
received:
07
05
2024
accepted:
08
09
2024
medline:
16
9
2024
pubmed:
16
9
2024
entrez:
16
9
2024
Statut:
aheadofprint
Résumé
Alkanes are high-energy hydrocarbons that are foreseen as next generation biofuels. Cyanobacteria are known to naturally synthesize C15-C19 alkanes; however, the titers are too low to make this a commercially viable process. Therefore, to leverage these photosynthetic platforms for improved alkane production, here we engineered three novel isolates of Synechococcus elongatus PCC 11801, PCC 11802, and IITB6. The two gene AAR-ADO alkane biosynthesis pathway was constructed by cloning the genes for acyl-ACP reductase (aar) and aldehyde deformylating oxygenase (ado) from S. elongatus PCC 7942 under the regulation of P
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e3509Subventions
Organisme : DBT-Pan IIT Centre for Bioenergy
ID : BT/PR41982/PBD/26/822/2021
Organisme : Department of Biotechnology, Ministry of Science and Technology, India
ID : BT/PR46982/PBD/26/835/2023
Informations de copyright
© 2024 American Institute of Chemical Engineers.
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