Genome-wide population affinities and signatures of adaptation in hydruntines, sussemiones and Asian wild asses.
ANTXR2
Asian wild ass
European wild ass
Sussemione
ancient DNA
extinction
Journal
Molecular ecology
ISSN: 1365-294X
Titre abrégé: Mol Ecol
Pays: England
ID NLM: 9214478
Informations de publication
Date de publication:
16 Sep 2024
16 Sep 2024
Historique:
revised:
08
06
2024
received:
28
11
2023
accepted:
03
09
2024
medline:
16
9
2024
pubmed:
16
9
2024
entrez:
16
9
2024
Statut:
aheadofprint
Résumé
The extremely rich palaeontological record of the horse family, also known as equids, has provided many examples of macroevolutionary change over the last ~55 Mya. This family is also one of the most documented at the palaeogenomic level, with hundreds of ancient genomes sequenced. While these data have advanced understanding of the domestication history of horses and donkeys, the palaeogenomic record of other equids remains limited. In this study, we have generated genome-wide data for 25 ancient equid specimens spanning over 44 Ky and spread across Anatolia, the Caucasus, Central Asia and Mongolia. Our dataset includes the genomes from two extinct species, the European wild ass, Equus hydruntinus, and the sussemione Equus ovodovi. We document, for the first time, the presence of sussemiones in Mongolia and their survival around ~3.9 Kya, a finding that should be considered when discussing the timing of the first arrival of the domestic horse in the region. We also identify strong spatial differentiation within the historical ecological range of Asian wild asses, Equus hemionus, and incomplete reproductive isolation in several groups yet considered as different species. Finally, we find common selection signatures at ANTXR2 gene in European, Asian and African wild asses. This locus, which encodes a receptor for bacterial toxins, shows no selection signal in E. ovodovi, but a 5.4-kb deletion within intron 7. Whether such genetic modifications played any role in the sussemione extinction remains unknown.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e17527Subventions
Organisme : European Union's Horizon 2020 research and innovation programme
ID : 101027750
Organisme : European Union's Horizon 2020 research and innovation programme
ID : 101062645
Organisme : Agricultural Science and Technology Innovation Program (ASTIP-05)
Organisme : CNRS and University Paul Sabatier (AnimalFarm IRP)
Organisme : Spanish Ministerio de Educación, Cultura y Deporte (Archaeological Projects Abroad 2017)
Organisme : Wroclaw Centre of Biotechnology programme ('The Leading National Research Center [KNOW]')
Organisme : HORIZON EUROPE European Research Council
ID : 681605
Organisme : HORIZON EUROPE European Research Council
ID : 834616
Organisme : HORIZON EUROPE European Research Council
ID : 101071707
Organisme : Agence Nationale pour la Recherche
ID : ANR-10-INBS-09
Organisme : Russian Science Foundation
ID : 19-78-10053
Organisme : Russian Science Foundation
ID : 22-18-00194
Informations de copyright
© 2024 The Author(s). Molecular Ecology published by John Wiley & Sons Ltd.
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