Oral rabies vaccination of foxes in Türkiye, 2019-2022.
Oral vaccination
Rabies
Red fox
SAD-B19
Türkiye
Journal
One health (Amsterdam, Netherlands)
ISSN: 2352-7714
Titre abrégé: One Health
Pays: Netherlands
ID NLM: 101660501
Informations de publication
Date de publication:
Dec 2024
Dec 2024
Historique:
received:
16
04
2024
revised:
31
07
2024
accepted:
13
08
2024
medline:
17
9
2024
pubmed:
17
9
2024
entrez:
16
9
2024
Statut:
epublish
Résumé
Rabies in Turkey is maintained by dogs, but following a sustained spill-over, red fox mediated rabies had spread from the Aegean region to the central part of Türkiye. During the past four years from 2019 to 2023 large scale efforts used oral rabies vaccination (ORV) to control rabies in red foxes. Here, we present the results of the largest ORV campaign on the Asian continent. ORV campaigns were carried out twice a year in spring and autumn with a targeted bait density of 20-23 baits/km Aerial bait distribution was highly accurate, with >99 % of baits being recorded from targeted zones, thus meeting the desired bait densities. Although the overall bait uptake (28.1 %; 95 %CI: 23.2-32.8) and seroprevalance (36.3 %; 95 %CI: 30.0-43.2) were low, rabies incidence drastically decreased in ORV areas and rabies was eliminated from western and central parts of Turkey, with no reported cases in foxes from ORV areas in 2022 and 2023. A large-scale ORV campaign against fox rabies using high quality vaccine baits and the GIS-aided and monitored bait distribution was able to control fox mediated rabies in the western and central parts of Türkiye. Rabies control both in dogs and foxes should be expanded to cover also the eastern parts of Türkiye, to become eventually rabies free.
Sections du résumé
Background
UNASSIGNED
Rabies in Turkey is maintained by dogs, but following a sustained spill-over, red fox mediated rabies had spread from the Aegean region to the central part of Türkiye. During the past four years from 2019 to 2023 large scale efforts used oral rabies vaccination (ORV) to control rabies in red foxes. Here, we present the results of the largest ORV campaign on the Asian continent.
Methods
UNASSIGNED
ORV campaigns were carried out twice a year in spring and autumn with a targeted bait density of 20-23 baits/km
Results
UNASSIGNED
Aerial bait distribution was highly accurate, with >99 % of baits being recorded from targeted zones, thus meeting the desired bait densities. Although the overall bait uptake (28.1 %; 95 %CI: 23.2-32.8) and seroprevalance (36.3 %; 95 %CI: 30.0-43.2) were low, rabies incidence drastically decreased in ORV areas and rabies was eliminated from western and central parts of Turkey, with no reported cases in foxes from ORV areas in 2022 and 2023.
Conclusions
UNASSIGNED
A large-scale ORV campaign against fox rabies using high quality vaccine baits and the GIS-aided and monitored bait distribution was able to control fox mediated rabies in the western and central parts of Türkiye. Rabies control both in dogs and foxes should be expanded to cover also the eastern parts of Türkiye, to become eventually rabies free.
Identifiants
pubmed: 39281344
doi: 10.1016/j.onehlt.2024.100877
pii: S2352-7714(24)00203-9
pmc: PMC11402421
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100877Informations de copyright
© 2024 The Authors. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
A.V. is a full-time employee of Ceva Innovation Center, formerly IDT Biologika, Germany, a company manufacturing oral rabies vaccine baits. T.M. and C.M.F. from the Friedrich-Loeffler-Institute received funding from IDT Biologika / Ceva for research into mechanisms of oral rabies vaccination and serological response. All the other authors declare no competing interests.