Multivariable model for gait pattern differentiation in elderly patients with hip and knee osteoarthritis: A wearable sensor approach.

Gait analysis Hip osteoarthritis Inertial measurement unit Knee osteoarthritis Wearable sensors

Journal

Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560

Informations de publication

Date de publication:
15 Sep 2024
Historique:
received: 13 05 2024
accepted: 22 08 2024
medline: 17 9 2024
pubmed: 17 9 2024
entrez: 16 9 2024
Statut: epublish

Résumé

Hip and knee osteoarthritis (OA) patients demonstrate distinct gait patterns, yet detecting subtle abnormalities with wearable sensors remains uncertain. This study aimed to assess a predictive model's efficacy in distinguishing between hip and knee OA gait patterns using accelerometer data. Participants with hip or knee OA underwent overground walking assessments, recording lower limb accelerations for subsequent time and frequency domain analyses. Logistic regression with regularization identified associations between frequency domain features of acceleration signals and OA, and k-nearest neighbor classification distinguished knee and hip OA based on selected acceleration signal features. We included 57 knee OA patients (30 females, median age 68 [range 49-89], median BMI 29.7 [range 21.0-45.9]) and 42 hip OA patients (19 females, median age 70 [range 47-89], median BMI 28.3 [range 20.4-37.2]). No significant difference could be found in the time domain's averaged shape of acceleration signals. However, in the frequency domain, five selected features showed a diagnostic ability to differentiate between knee and hip OA. Using these features, a model achieved a 77 % accuracy in classifying gait cycles into hip or knee OA groups, with average precision, recall, and F1 score of 77 %, 76 %, and 78 %, respectively. The study demonstrates the effectiveness of wearable sensors in differentiating gait patterns between individuals with hip and knee OA, specifically in the frequency domain. The results highlights the promising potential of wearable sensors and advanced signal processing techniques for objective assessment of OA in clinical settings.

Sections du résumé

Background UNASSIGNED
Hip and knee osteoarthritis (OA) patients demonstrate distinct gait patterns, yet detecting subtle abnormalities with wearable sensors remains uncertain. This study aimed to assess a predictive model's efficacy in distinguishing between hip and knee OA gait patterns using accelerometer data.
Method UNASSIGNED
Participants with hip or knee OA underwent overground walking assessments, recording lower limb accelerations for subsequent time and frequency domain analyses. Logistic regression with regularization identified associations between frequency domain features of acceleration signals and OA, and k-nearest neighbor classification distinguished knee and hip OA based on selected acceleration signal features.
Findings UNASSIGNED
We included 57 knee OA patients (30 females, median age 68 [range 49-89], median BMI 29.7 [range 21.0-45.9]) and 42 hip OA patients (19 females, median age 70 [range 47-89], median BMI 28.3 [range 20.4-37.2]). No significant difference could be found in the time domain's averaged shape of acceleration signals. However, in the frequency domain, five selected features showed a diagnostic ability to differentiate between knee and hip OA. Using these features, a model achieved a 77 % accuracy in classifying gait cycles into hip or knee OA groups, with average precision, recall, and F1 score of 77 %, 76 %, and 78 %, respectively.
Interpretation UNASSIGNED
The study demonstrates the effectiveness of wearable sensors in differentiating gait patterns between individuals with hip and knee OA, specifically in the frequency domain. The results highlights the promising potential of wearable sensors and advanced signal processing techniques for objective assessment of OA in clinical settings.

Identifiants

pubmed: 39281497
doi: 10.1016/j.heliyon.2024.e36825
pii: S2405-8440(24)12856-3
pmc: PMC11395743
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e36825

Informations de copyright

© 2024 The Authors.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Arash Ghaffari (A)

Interdisciplinary Orthopaedics, Aalborg University Hospital, Aalborg, Denmark.

Pernille Damborg Clasen (PD)

Interdisciplinary Orthopaedics, Aalborg University Hospital, Aalborg, Denmark.

Rikke Vindberg Boel (RV)

Interdisciplinary Orthopaedics, Aalborg University Hospital, Aalborg, Denmark.

Andreas Kappel (A)

Interdisciplinary Orthopaedics, Aalborg University Hospital, Aalborg, Denmark.

Thomas Jakobsen (T)

Interdisciplinary Orthopaedics, Aalborg University Hospital, Aalborg, Denmark.

John Rasmussen (J)

Department of Materials and Production, Aalborg University, Aalborg East, Denmark.

Søren Kold (S)

Interdisciplinary Orthopaedics, Aalborg University Hospital, Aalborg, Denmark.

Ole Rahbek (O)

Interdisciplinary Orthopaedics, Aalborg University Hospital, Aalborg, Denmark.

Classifications MeSH