Endothelial derived, secreted long non-coding RNAs

MT:Non-coding RNAs calcium/calmodulin-dependent protein kinase type II cardiac angiogenesis extracellular vesicles heart failure hypertrophy

Journal

Molecular therapy. Nucleic acids
ISSN: 2162-2531
Titre abrégé: Mol Ther Nucleic Acids
Pays: United States
ID NLM: 101581621

Informations de publication

Date de publication:
10 Sep 2024
Historique:
received: 30 01 2024
accepted: 12 08 2024
medline: 17 9 2024
pubmed: 17 9 2024
entrez: 16 9 2024
Statut: epublish

Résumé

Pathological cardiac remodeling predisposes individuals to developing heart failure. Here, we investigated two co-regulated long non-coding RNAs (lncRNAs), termed

Identifiants

DOI: 10.1016/j.omtn.2024.102306 PMID: 39281699 PMC: PMC11402397
pubmed: 39281699
doi: 10.1016/j.omtn.2024.102306
pii: S2162-2531(24)00193-8
pmc: PMC11402397
doi:

Types de publication

Journal Article

Langues

eng

Pagination

102306

Informations de copyright

© 2024 The Author(s).

Déclaration de conflit d'intérêts

The patent for the use of lncRNA Gadlor1 and Gadlor2 in treating and preventing cardiac remodeling has been granted to N. Froese, J.B., and J.H. (US11208656, granted on 28.01.2021).

Auteurs

Merve Keles (M)

ECAS (European Center for Angioscience), Department of Cardiovascular Physiology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.
CFPM (Core Facility Platform Mannheim), Cardiac Imaging Center, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.
DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Steve Grein (S)

ECAS (European Center for Angioscience), Department of Cardiovascular Physiology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.
DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Natali Froese (N)

Department of Cardiology and Angiology, Hannover Medical School, 30625 Hannover, Germany.

Dagmar Wirth (D)

Helmholtz Center for Infection Research, Model Systems for Infection and Immunity, 38124 Braunschweig, Germany.

Felix A Trogisch (FA)

ECAS (European Center for Angioscience), Department of Cardiovascular Physiology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.
CFPM (Core Facility Platform Mannheim), Cardiac Imaging Center, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.
DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Rhys Wardman (R)

ECAS (European Center for Angioscience), Department of Cardiovascular Physiology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.
DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Shruthi Hemanna (S)

ECAS (European Center for Angioscience), Department of Cardiovascular Physiology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.
DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Nina Weinzierl (N)

ECAS (European Center for Angioscience), Department of Cardiovascular Physiology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.

Philipp-Sebastian Koch (PS)

Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Stefanie Uhlig (S)

CFPM, FlowCore, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.

Santosh Lomada (S)

DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.
ECAS, Department of Experimental Pharmacology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.

Gesine M Dittrich (GM)

ECAS (European Center for Angioscience), Department of Cardiovascular Physiology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.
DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Malgorzata Szaroszyk (M)

Department of Cardiology and Angiology, Hannover Medical School, 30625 Hannover, Germany.

Ricarda Haustein (R)

Department of Cardiology and Angiology, Hannover Medical School, 30625 Hannover, Germany.

Jan Hegermann (J)

Institute of Functional and Applied Anatomy, Core Unit Electron Microscopy, Hannover Medical School, 30625 Hannover, Germany.

Abel Martin-Garrido (A)

ECAS (European Center for Angioscience), Department of Cardiovascular Physiology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.

Johann Bauersachs (J)

Department of Cardiology and Angiology, Hannover Medical School, 30625 Hannover, Germany.

Derk Frank (D)

Department of Internal Medicine III, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.
DZHK, partner site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.

Norbert Frey (N)

DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.
Department of Internal Medicine III, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.

Karen Bieback (K)

CFPM, FlowCore, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.

Julio Cordero (J)

ECAS, Department of Cardiovascular Genomics and Epigenomics, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.

Gergana Dobreva (G)

DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.
ECAS, Department of Cardiovascular Genomics and Epigenomics, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.

Thomas Wieland (T)

DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.
ECAS, Department of Experimental Pharmacology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.

Joerg Heineke (J)

ECAS (European Center for Angioscience), Department of Cardiovascular Physiology, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.
CFPM (Core Facility Platform Mannheim), Cardiac Imaging Center, Medical Faculty Mannheim of Heidelberg University, 68167 Mannheim, Germany.
DZHK (German Center for Cardiovascular Research), partner site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Classifications MeSH