Radical chemoradiotherapy for superficial esophageal cancer complicated with liver cirrhosis.
Liver cirrhosis
Radical chemoradiotherapy
Retrospective study
Superficial esophageal cancer
Journal
PeerJ
ISSN: 2167-8359
Titre abrégé: PeerJ
Pays: United States
ID NLM: 101603425
Informations de publication
Date de publication:
2024
2024
Historique:
received:
17
04
2024
accepted:
19
08
2024
medline:
17
9
2024
pubmed:
17
9
2024
entrez:
16
9
2024
Statut:
epublish
Résumé
Although chemoradiotherapy is an effective treatment for esophageal cancer, its feasibility in esophageal cancer with cirrhosis remains largely unclear. We retrospectively studied 11 patients with superficial esophageal cancer with liver cirrhosis (Child-Pugh score ≤8) who underwent radical chemoradiotherapy from four centers, and the overall survival rate, local control rate and adverse events at 1 and 3 years were explored. The median age of the included patients was 67 years (Inter-Quartile Range 60-75 years). Complete response was observed in most patients ( Radical chemoradiotherapy is a potential treatment option for patients with superficial esophageal cancer complicated with cirrhosis. However, it can increase the risk of bleeding, which warrants prompt recognition and intervention.
Sections du résumé
Background
UNASSIGNED
Although chemoradiotherapy is an effective treatment for esophageal cancer, its feasibility in esophageal cancer with cirrhosis remains largely unclear.
Methods
UNASSIGNED
We retrospectively studied 11 patients with superficial esophageal cancer with liver cirrhosis (Child-Pugh score ≤8) who underwent radical chemoradiotherapy from four centers, and the overall survival rate, local control rate and adverse events at 1 and 3 years were explored.
Results
UNASSIGNED
The median age of the included patients was 67 years (Inter-Quartile Range 60-75 years). Complete response was observed in most patients (
Conclusion
UNASSIGNED
Radical chemoradiotherapy is a potential treatment option for patients with superficial esophageal cancer complicated with cirrhosis. However, it can increase the risk of bleeding, which warrants prompt recognition and intervention.
Identifiants
pubmed: 39282115
doi: 10.7717/peerj.18065
pii: 18065
pmc: PMC11401512
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
e18065Informations de copyright
© 2024 Bao et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.