Harnessing glycofluoroforms for impedimetric biosensing.
Journal
Chemical science
ISSN: 2041-6520
Titre abrégé: Chem Sci
Pays: England
ID NLM: 101545951
Informations de publication
Date de publication:
13 Sep 2024
13 Sep 2024
Historique:
received:
03
07
2024
accepted:
04
09
2024
medline:
17
9
2024
pubmed:
17
9
2024
entrez:
16
9
2024
Statut:
aheadofprint
Résumé
Glycans play a major role in biological cell-cell recognition and signal transduction but have found limited application in biosensors due to glycan/lectin promiscuity; multiple proteins are capable of binding to the same native glycan. Here, site-specific fluorination is used to introduce protein-glycan selectivity, and this is coupled with an electrochemical detection method to generate a novel biosensor platform. 3F-lacto-
Identifiants
pubmed: 39282644
doi: 10.1039/d4sc04409f
pii: d4sc04409f
pmc: PMC11393611
doi:
Types de publication
Journal Article
Langues
eng
Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.