The relationship between Parkinson's disease and sexual hyperactivity secondary to drug treatment: A systematic review.

Parkinson’s disease clinical trials hypersexual behavior pharmacological treatment risk factors

Journal

Journal of psychopharmacology (Oxford, England)
ISSN: 1461-7285
Titre abrégé: J Psychopharmacol
Pays: United States
ID NLM: 8907828

Informations de publication

Date de publication:
16 Sep 2024
Historique:
medline: 17 9 2024
pubmed: 17 9 2024
entrez: 16 9 2024
Statut: aheadofprint

Résumé

This review addresses the prevalence of hypersexual behavior in Parkinson's patients and the underlying neurobiological mechanisms, identifying risk and protective factors, comparing incidence among different treatments, and proposing recommendations for management and prevention. To conduct a review on the relationship between Parkinson's disease and hypersexual behavior as a result of pharmacological treatment. The search strategy, guided by PRISMA and PICOS criteria, focuses on the correlation between Parkinson's disease and hypersexual behavior due to pharmacological treatment. Utilizing databases like PubMed and Proquest, studies from the last 10 years in English or Spanish were selected, emphasizing clinical trials with Parkinson's patients under treatment. Inaccessible, irrelevant, or mixed-sample studies were excluded. The Cochrane Scale assessed the risk of bias. Out of 122 records, 103 remained after eliminating duplicates; 48 were reviewed, and ultimately, 6 studies met the inclusion criteria for analysis. Synthesizing the risk and protective factors linked to hypersexual behavior in Parkinson's patients receiving pharmacological treatment underscores the critical need for early detection and incorporation of these factors into clinical care. The suggested guidelines for managing and preventing hypersexual behavior in these patients carry substantial practical implications.

Identifiants

pubmed: 39282911
doi: 10.1177/02698811241277200
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2698811241277200

Déclaration de conflit d'intérêts

Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Verónica Aparicio-López (V)

Universidad Internacional de Valencia, Valencia, Spain.

María Rueda-Extremera (M)

Faculty of Health Sciences and Education, Universidad a Distancia de Madrid (UDIMA), Collado Villalba, Spain.

María Cantero-García (M)

Faculty of Health Sciences and Education, Universidad a Distancia de Madrid (UDIMA), Collado Villalba, Spain.

Classifications MeSH