Effect of Age on the Pharmacokinetics of Marbofloxacin Following Intravenous Administration in Calves.

age calves marbofloxacin pharmacodynamics pharmacokinetics

Journal

Journal of veterinary pharmacology and therapeutics
ISSN: 1365-2885
Titre abrégé: J Vet Pharmacol Ther
Pays: England
ID NLM: 7910920

Informations de publication

Date de publication:
17 Sep 2024
Historique:
revised: 18 08 2024
received: 06 07 2024
accepted: 02 09 2024
medline: 17 9 2024
pubmed: 17 9 2024
entrez: 17 9 2024
Statut: aheadofprint

Résumé

The aim of this study was to compare the pharmacokinetics of marbofloxacin after intravenous (IV) administration of a single dose of 10 mg/kg to calves of different ages. The study was carried on 1- (n = 6), 2- (n = 6), and 4-month-old (n = 6) Montofon calves. Plasma concentrations of marbofloxacin were measured using HPLC, and pharmacokinetic data were calculated by non-compartmental analysis. The elimination half-life (t

Identifiants

pubmed: 39285847
doi: 10.1111/jvp.13483
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 John Wiley & Sons Ltd.

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Auteurs

Orhan Corum (O)

Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Hatay Mustafa Kemal, Hatay, Turkiye.

Murat Yuksel (M)

Department of Obstetrics and Gyneacology, Faculty of Veterinary Medicine, University of Hatay Mustafa Kemal, Hatay, Turkiye.

Devran Coskun (D)

Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Siirt, Siirt, Turkiye.

Duygu Durna Corum (D)

Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Hatay Mustafa Kemal, Hatay, Turkiye.

Serafettin Kartal (S)

Department of Veterinary Medicine, Samandag Vocational School, Hatay Mustafa Kemal University, Hatay, Turkiye.

Mustafa Cellat (M)

Department of Physiology, Faculty of Veterinary Medicine, University of Hatay Mustafa Kemal, Hatay, Turkiye.

Kamil Uney (K)

Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Selcuk, Konya, Turkiye.

Classifications MeSH