Quick and effective approximation of in silico saturation mutagenesis experiments with first-order taylor expansion.

To understand the decision process of genomic sequence-to-function models, explainable AI algorithms determine the importance of each nucleotide in a given input sequence to the model's predictions and enable discovery of

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© 2024 The Author(s). Published by Elsevier Inc.

Déclaration de conflit d'intérêts

The authors declare no competing interest.