Vasopressor use in partial flap necrosis in free flap transplant patients with vascular comorbidities: A retrospective study.

Free flap Microsurgery Reconstructive surgery Vasopressors

Journal

JPRAS open
ISSN: 2352-5878
Titre abrégé: JPRAS Open
Pays: Netherlands
ID NLM: 101680420

Informations de publication

Date de publication:
Sep 2024
Historique:
received: 10 04 2024
accepted: 30 06 2024
medline: 17 9 2024
pubmed: 17 9 2024
entrez: 17 9 2024
Statut: epublish

Résumé

Intraoperative use of vasopressors in free flap surgeries is controversially debated. The predominant concern is that pedicle blood supply will decrease leading to post-operative complications. This study examined the role of intraoperative vasopressors, specifically norepinephrine, in free flap partial necrosis based on the patients' comorbidities. We retrospectively analyzed 192 patients who received free flap treatment between 2006 and 2021 and were stratified based on vascular comorbidities. We assessed the role of intraoperative vasopressors using multivariate analysis. Patients who were administered vasopressors did not have a significantly higher risk of partial flap necrosis compared to patients who were not administered vasopressors (OR: 1.439, 95% CI: 0.618-3.348,

Identifiants

pubmed: 39286577
doi: 10.1016/j.jpra.2024.06.018
pii: S2352-5878(24)00093-7
pmc: PMC11403112
doi:

Types de publication

Journal Article

Langues

eng

Pagination

276-284

Informations de copyright

© 2024 The Author(s).

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Auteurs

Nadjib Dastagir (N)

Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hannover Medical School, 30625, Hannover, Germany.

Doha Obed (D)

Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hannover Medical School, 30625, Hannover, Germany.

Florian Bucher (F)

Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hannover Medical School, 30625, Hannover, Germany.

Jana L Schmidt (JL)

Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hannover Medical School, 30625, Hannover, Germany.

Khaled Dastagir (K)

Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hannover Medical School, 30625, Hannover, Germany.

Peter M Vogt (PM)

Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hannover Medical School, 30625, Hannover, Germany.

Classifications MeSH