Characterizations of Protein Arginine Deiminase 1 as a Substrate of NTMT1: Implications of Nα-Methylation in Protein Stability and Interaction.

NTMT1 Nα-methylation PAD1 protein stability protein−protein interactions

Journal

Journal of proteome research
ISSN: 1535-3907
Titre abrégé: J Proteome Res
Pays: United States
ID NLM: 101128775

Informations de publication

Date de publication:
17 Sep 2024
Historique:
medline: 17 9 2024
pubmed: 17 9 2024
entrez: 17 9 2024
Statut: aheadofprint

Résumé

α-N-Methylation (Nα-methylation), catalyzed by protein N-terminal methyltransferases (NTMTs), constitutes a crucial post-translational modification involving the transfer of a methyl group from

Identifiants

DOI: 10.1021/acs.jproteome.4c00484 PMID: 39287128
pubmed: 39287128
doi: 10.1021/acs.jproteome.4c00484
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Ying Meng (Y)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue Institute for Drug Discovery, Purdue University Center for Cancer Research, Purdue University, 720 Clinic Drive, West Lafayette, Indiana 47907, United States.

Zhouxian Li (Z)

Department of Chemistry, University of California Riverside, 501 Big Springs Road, Riverside, California 92521, United States.

Ming He (M)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue Institute for Drug Discovery, Purdue University Center for Cancer Research, Purdue University, 720 Clinic Drive, West Lafayette, Indiana 47907, United States.

Quanqing Zhang (Q)

Department of Chemistry, University of California Riverside, 501 Big Springs Road, Riverside, California 92521, United States.

Youchao Deng (Y)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue Institute for Drug Discovery, Purdue University Center for Cancer Research, Purdue University, 720 Clinic Drive, West Lafayette, Indiana 47907, United States.

Yinsheng Wang (Y)

Department of Chemistry, University of California Riverside, 501 Big Springs Road, Riverside, California 92521, United States.

Rong Huang (R)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue Institute for Drug Discovery, Purdue University Center for Cancer Research, Purdue University, 720 Clinic Drive, West Lafayette, Indiana 47907, United States.
ORCID: 0000-0002-1477-3165

Classifications MeSH