IMAGING PREDICTORS OF FUNCTIONAL OUTCOMES AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR.
Humans
Retinal Detachment
/ surgery
Retrospective Studies
Visual Acuity
/ physiology
Tomography, Optical Coherence
/ methods
Female
Male
Middle Aged
Vitrectomy
Fluorescein Angiography
/ methods
Aged
Vision Disorders
/ physiopathology
Scleral Buckling
/ methods
Adult
Fundus Oculi
Postoperative Period
Follow-Up Studies
Journal
Retina (Philadelphia, Pa.)
ISSN: 1539-2864
Titre abrégé: Retina
Pays: United States
ID NLM: 8309919
Informations de publication
Date de publication:
01 Oct 2024
01 Oct 2024
Historique:
medline:
17
9
2024
pubmed:
17
9
2024
entrez:
17
9
2024
Statut:
ppublish
Résumé
To evaluate the microstructural optical coherence tomography and fundus autofluorescence imaging predictors of visual acuity, metamorphopsia, and aniseikonia following rhegmatogenous retinal detachment repair. This is a multicenter retrospective study of patients with primary rhegmatogenous retinal detachment who underwent repair. Best-corrected visual acuity, metamorphopsia, and aniseikonia were formally tested at 3 months postoperatively. Metamorphopsia and aniseikonia were quantitatively assessed with M-CHARTS and the New Aniseikonia Test, respectively. High-resolution spectral-domain optical coherence tomography and fundus autofluorescence images were obtained at 3 months postoperatively. Images were assessed for discontinuity of the outer retinal bands on optical coherence tomography and retinal displacement detected by retinal vessel printings on fundus autofluorescence by two masked graders with disagreements adjudicated by a third senior masked grader. Multiple linear regression models were used to determine the predictors of postoperative visual acuity, metamorphopsia, and aniseikonia. Six hundred fourteen eyes of 614 patients were included in this study. Regression analysis indicated that significant early postoperative (at 3 months) imaging predictors of visual acuity were discontinuity of the external limiting membrane (P = 0.001) and the presence of retinal vessel printings on fundus autofluorescence (P = 0.033). Discontinuity of interdigitation zone was a significant predictor of metamorphopsia [horizontal metamorphopsia (P =0.004); vertical metamorphopsia (P = 0.056); average of horizontal metamorphopsia + vertical metamorphopsia (P = 0.008)], and presence of retinal vessel printings was a significant predictor of aniseikonia (P = 0.04). Discontinuity of the external limiting membrane and retinal displacement were significant predictors of postoperative visual acuity following rhegmatogenous retinal detachment repair. Discontinuity of the interdigitation zone and retinal displacement were significant predictors of metamorphopsia and aniseikonia, respectively.
Identifiants
pubmed: 39287538
doi: 10.1097/IAE.0000000000004172
pii: 00006982-202410000-00012
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1758-1765Références
Okamoto F, Sugiura Y, Okamoto Y, et al. Metamorphopsia and optical coherence tomography findings after Rhegmatogenous retinal detachment surgery. Am J Ophthalmol 2014;157:214–220.e1.
Nork TM, Millecchia LL, Strickland BD, et al. Selective loss of blue cones and rods in human retinal detachment. Arch Ophthalmol 1995;113:1066–1073.
Dell'omo R, Cifariello F, Dell'omo E, et al. Influence of retinal vessel printings on metamorphopsia and retinal architectural abnormalities in eyes with idiopathic macular epiretinal membrane. Invest Ophthalmol Vis Sci 2013;54:7803–7811.
Okuda T, Higashide T, Sugiyama K. Metamorphopsia and outer retinal morphologic changes after successful vitrectomy surgery for macula-off rhegmatogenous retinal detachment. Retina 2018;38:148–154.
Murakami T, Okamoto F, Sugiura Y, et al. Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery. Sci Rep 2019;9:11588.
Okamoto F, Sugiura Y, Okamoto Y, et al. Aniseikonia and foveal microstructure after retinal detachment surgery. Invest Ophthalmol Vis Sci 2014;17:IOVS-14-14618.
van de Put MAJ, Vehof J, Hooymans JMM, Los LI. Postoperative metamorphopsia in macula-off rhegmatogenous retinal detachment: associations with visual function, vision related quality of life, and optical coherence tomography findings. PLoS One 2015;10:e0120543.
Zhou C, Lin Q, Chen F. Prevalence and predictors of metamorphopsia after successful rhegmatogenous retinal detachment surgery: a cross-sectional, comparative study. Br J Ophthalmol 2016;101:725–729.
Lee E, Williamson TH, Hysi P, et al. Macular displacement following rhegmatogenous retinal detachment repair. Br J Ophthalmol 2013;97:1297–1302.
Schawkat M, Valmaggia C, Lang C, et al. Multimodal imaging for detecting metamorphopsia after successful retinal detachment repair. Graefes Arch Clin Exp Ophthalmol 2020;258:57–61.
Francisconi CLM, Marafon SB, Figueiredo NA, et al. Retinal displacement after pneumatic retinopexy versus vitrectomy for rhegmatogenous retinal detachment (ALIGN). Ophthalmology 2022;129:458–461.
Rossetti A, Doro D, Manfre A, Midena E. Long-term follow-up with optical coherence tomography and microperimetry in eyes with metamorphopsia after macula-off retinal detachment repair. Eye (Lond) 2010;24:1808–1813.
Wang Y, Li SY, Zhu M, et al. Metamorphopsia after successful retinal detachment surgery: an optical coherence tomography study. Acta Ophthalmol Scand 2005;83:168–171.
Sjöstrand J, Anderson C. Micropsia and metamorphopsia in the re-attached macula following retinal detachment. Acta Ophthalmol (Copenh) 1986;64:425–432.
Ng H, Vermeer KA, van Meurs JC, La Heij EC. Visual acuity inadequately reflects vision-related quality of life in patients after macula-off retinal detachment surgery. Invest Ophthalmol Vis Sci 2020;61:34.
Hillier RJ, Felfeli T, Berger AR, et al. The pneumatic retinopexy versus vitrectomy for the management of primary rhegmatogenous retinal detachment outcomes randomized trial (PIVOT). Ophthalmology 2019;126:531–539.
Kobayashi M, Iwase T, Yamamoto K, et al. Association between photoreceptor regeneration and visual acuity following surgery for rhegmatogenous retinal detachment. Invest Ophthalmol Vis Sci 2016;57:889–898.
Wakabayashi T, Oshima Y, Fujimoto H, et al. Foveal microstructure and visual acuity after retinal detachment repair: imaging analysis by Fourier-domain optical coherence tomography. Ophthalmology 2009;116:519–528.
Shimoda Y, Sano M, Hashimoto H, et al. Restoration of photoreceptor outer segment after vitrectomy for retinal detachment. Am J Ophthalmol 2009;149:284–290.
Kobayashi M, Iwase T, Yamamoto K, et al. Perioperative factors that are significantly correlated with final visual acuity in eyes after successful rhegmatogenous retinal detachment surgery. PLoS One 2017;12:e0184783.
Kang HM, Lee SC, Lee CS. Association of spectral-domain optical coherence tomography findings with visual outcome of macula-off rhegmatogenous retinal detachment surgery. Ophthalmologica 2015;234:83–90.
Casswell EJ, Yorston D, Lee E, et al. Effect of face-down positioning vs support-the-break positioning after macula-involving retinal detachment repair: the PostRD randomized clinical trial. JAMA Ophthalmol 2020;138:634–642.
Terauchi G, Shinoda K, Matsumoto CS, et al. Recovery of photoreceptor inner and outer segment layer thickness after reattachment of rhegmatogenous retinal detachment. Br J Ophthalmol 2015;99:1323–1327.
Murakami T, Okamoto F, Sugiura Y, et al. Changes in metamorphopsia and optical coherence tomography findings after successful retinal detachment surgery. Retina 2018;38:684–691.
Muni RH, Felfeli T, Sadda SR, et al. Postoperative photoreceptor integrity following pneumatic retinopexy vs pars plana vitrectomy for retinal detachment repair: a post hoc optical coherence tomography analysis from the pneumatic retinopexy versus vitrectomy for the management of primary rhegmatogenous retinal detachment outcomes randomized trial. JAMA Ophthalmol 2021;139:620–627.
Gharbiya M, Grandinetti F, Scavella V, et al. Correlation between spectral-domain optical coherence tomography findings and visual outcome after primary rhegmatogenous retinal detachment repair. Retina 2012;32:43–53.
Lewis GP, Charteris DG, Sethi CS, Fisher SK. Animal models of retinal detachment and reattachment: identifying cellular events that may affect visual recovery. Eye (Lond) 2002;16:375–387.
Brosh K, Francisconi CLM, Qian J, et al. Retinal displacement following pneumatic retinopexy vs pars plana vitrectomy for rhegmatogenous retinal detachment. JAMA Ophthalmol 2020;138:652–659.
Bansal A, Naidu SC, Marafon SB, et al. Retinal displacement after scleral buckle versus combined buckle and vitrectomy for rhegmatogenous retinal detachment: ALIGN scleral buckle versus pars plana vitrectomy with scleral buckle. Ophthalmol Retina 2023;7:788–793.
Farahvash A, Marafon SB, Juncal VR, et al. Impact of tamponade agent on retinal displacement following pars plana vitrectomy for rhegmatogenous retinal detachment repair: a computer simulation model. Acta Ophthalmol 2022;100:e1470–e1478.
McKay BR, Bansal A, Kryshtalskyj M, et al. Evaluation of subretinal fluid drainage techniques during pars plana vitrectomy for primary rhegmatogenous retinal detachment-ellipsoid study. Am J Ophthalmol 2022;241:227–237.