P
Bioenergetic system
Critical power
Maximal oxygen uptake
Metabolite homeostasis
Oxidative phosphorylation
Skeletal muscle
Journal
European journal of applied physiology
ISSN: 1439-6327
Titre abrégé: Eur J Appl Physiol
Pays: Germany
ID NLM: 100954790
Informations de publication
Date de publication:
17 Sep 2024
17 Sep 2024
Historique:
received:
11
12
2023
accepted:
10
07
2024
medline:
17
9
2024
pubmed:
17
9
2024
entrez:
17
9
2024
Statut:
aheadofprint
Résumé
Endurance training improves running performance in distances where oxidative phosphorylation (OXPHOS) is the main ATP source. Here, a dynamic computer model is used to assess possible biochemical mechanisms underlying this improvement. The dynamic computer model is based on the "P The endurance-training-induced increase in oxidative phosphorylation (OXPHOS) activity attenuates the reaching of Pi The present dynamic computer model generates clear predictions of metabolic changes that limit performance during 1500 m running. It contributes to our mechanistic understanding of training-induced improvement in running performance and stimulates further physiological experimental studies.
Identifiants
pubmed: 39287637
doi: 10.1007/s00421-024-05560-w
pii: 10.1007/s00421-024-05560-w
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
Allen DG, Westerblad H (2001) Role of phosphate and calcium stores in muscle fatigue. J Physiol 536:657–665. https://doi.org/10.1111/j.1469-7793.2001.t01-1-00657.x
pubmed: 11691862
pmcid: 2278904
Allen DG, Lamb GD, Westerblad H (2008) Skeletal muscle fatigue: cellular mechanisms. Physiol Rev 88:287–332. https://doi.org/10.1152/physrev.00015.2007
pubmed: 18195089
Baldwin KM, Klinkerfuss GH, Terjung RL, Molé PA, Holloszy JO (1972) Respiratory capacity of white, red, and intermediate muscle: adaptative response to exercise. Am J Physiol 222:373–378. https://doi.org/10.1152/ajplegacy.1972.222.2.373
pubmed: 4333578
Berger NJ, Tolfrey K, Williams AG, Jones AM (2006) Influence of continuous and interval training on oxygen uptake on-kinetics. Med Sci Sports Exerc 38:504–512. https://doi.org/10.1249/01.mss.0000191418.37709.81
pubmed: 16540838
Burnley M, Jones AM (2007) Oxygen uptake kinetics as a determinant of sports performance. Eu J Sport Sci 7:63–79. https://doi.org/10.1123/ijspp.4.4.524
Carter H, Jones AM, Barstow TJ, Burnley M, Williams C, Dous JH (2000) Effect of endurance training: on oxygen uptake kinetics during treadmill running. J Appl Physiol 89:1744–1752. https://doi.org/10.1152/jappl.2000.89.5.1744
pubmed: 11053321
Casaburi R, Storer TW, Ben-Dov I, Wasserman K (1987) Effect of endurance training on possible determinants of V̇O
pubmed: 3558181
Clanton TL, Hogan M, Gladden LB (2013) Endurance training in humans: aerobic capacity and structure of skeletal muscle. Compr Physiol 3:1135–1190. https://doi.org/10.1002/cphy.c120030
pubmed: 23897683
Fernström M, Tonkonogi M, Sahlin K (2004) Effects of acute and chronic endurance exercise on mitochondrial uncoupling in human skeletal muscle. J Physiol 554:755–763. https://doi.org/10.1113/jphysiol.2003.055202
pubmed: 14634202
Gaesser GA, Wilson LA (1988) Effects of continuous and interval training on the parameters of the power-endurance time relationship for high-intensity exercise. Int J Sports Med 9:417–421. https://doi.org/10.1055/s-2007-1025043
pubmed: 3253231
Holloszy JO (1967) Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. J Biol Chem 242:2278–2282. https://doi.org/10.1016/S0021-9258(18)96046-1
pubmed: 4290225
Hoppeler H, Howald H, Conley K, Lindsted SL, Claassen H, Vock P, Weibel ER (1985) Endurance training in humans: aerobic capacity and structure of skeletal muscle. J Appl Physiol 59:320–327. https://doi.org/10.1152/jappl.1985.59.2.320
pubmed: 4030584
Hottenrott K, Ludyga S, Schulze S (2012) Effects of high intensity training and continuous endurance training on aerobic capacity and body composition in recreationally active runners. J Sports Sci Med 11:483–488
pubmed: 24149357
pmcid: 3737930
Hureau TJ, Broxterman RM, Weavil JC, Lewis MT, Layec G, Amann M (2022) On the role of skeletal muscle acidosis and inorganic phosphates as determinants of central and peripheral fatigue: a
pubmed: 35593645
Jacobs RA, Flück D, Bonne TC, Bürgi S, Christensen PM, Toigo M, Lundby C (2013) Improvements in exercise performance with high-intensity interval training coincide with an increase in skeletal muscle mitochondrial content and function. J Appl Physiol 115:785–793. https://doi.org/10.1152/japplphysiol.00445.2013
pubmed: 23788574
Jenkins DG, Quigley BM (1992) Endurance training enhances critical power. Med Sci Sports Exerc 24:1283–1289
pubmed: 1435180
Korzeniewski B (1998) Regulation of ATP supply during muscle contraction: theoretical studies. Biochem J 330:1189–1195. https://doi.org/10.1042/bj3301189
pubmed: 9494084
pmcid: 1219260
Korzeniewski B (2007) Regulation of oxidative phosphorylation through parallel activation. Biophys Chem 129:93–110. https://doi.org/10.1016/j.bpc.2007.05.013
pubmed: 17566629
Korzeniewski B (2017) Regulation of oxidative phosphorylation through each-step activation (ESA): evidences from computer modeling. Prog Biophys Mol Biol 125:1–23. https://doi.org/10.1016/j.pbiomolbio.2016.12.001
pubmed: 27939921
Korzeniewski B (2018a) Muscle V̇O
pmcid: 6234149
Korzeniewski B (2018b) Regulation of oxidative phosphorylation is different in electrically- and cortically-stimulated skeletal muscle. PLoS ONE 13:e0195620. https://doi.org/10.1371/journal.pone.0195620
pubmed: 29698403
pmcid: 5919680
Korzeniewski B (2019) P
pubmed: 31399839
Korzeniewski B (2021) Mechanisms of the effect of oxidative phosphorylation deficiencies on the skeletal muscle bioenergetic system. J Appl Physiol 131:768–777. https://doi.org/10.1152/japplphysiol.00196.2021
pubmed: 34197225
Korzeniewski B (2022) Effect of training on skeletal muscle bioenergetic system in patients with mitochondrial myopathies: a computational study. Resp Physiol Neurobiol 296:103799. https://doi.org/10.1016/j.resp.2021.103799
Korzeniewski B (2023a) Sensitivity of [Formula: see text]̇O
Korzeniewski B (2023b) Training-induced increase in [Formula: see text]̇O
Korzeniewski B, Liguzinski P (2004) Theoretical studies on the regulation of anaerobic glycolysis and its influence on oxidative phosphorylation in skeletal muscle. Biophys Chem 110:147–169. https://doi.org/10.1016/j.bpc.2004.01.011
pubmed: 15223151
Korzeniewski B, Rossiter HB (2015) Each-step activation of oxidative phosphorylation is necessary to explain muscle metabolite kinetic responses to exercise and recovery in humans. J Physiol 593:5255–5268. https://doi.org/10.1113/JP271299
pubmed: 26503399
pmcid: 4704516
Korzeniewski B, Rossiter HB (2020) Exceeding a “critical” P
pubmed: 32435984
Korzeniewski B, Rossiter HB (2021) Factors determining training-induced changes in [Formula: see text]̇O
pubmed: 33211591
Korzeniewski B, Rossiter HB (2022) Skeletal muscle biochemical origin of exercise intensity domains and their relation to whole-body [Formula: see text]̇O
pubmed: 35880531
pmcid: 9366749
Korzeniewski B, Zoladz JA (2001) A model of oxidative phosphorylation in mammalian skeletal muscle. Biophys Chem 92:17–34. https://doi.org/10.1016/s0301-4622(01)00184-3
pubmed: 11527576
Korzeniewski B, Zoladz JA (2003) Possible factors determining the non-linearity in the VO
Krieger DA, Tate CA, McMillin-Wood J, Booth FW (1980) Populations of rat skeletal muscle mitochondria after exercise and immobilization. J Appl Physiol 48:23–28. https://doi.org/10.1152/jappl.1980.48.1.23
pubmed: 6444398
Krustrup P, Jones AM, Wilkerson DP, Calbet JA, Bangsbo J (2009) Muscular and pulmonary O
pubmed: 19255119
pmcid: 2683969
McDonough P, Behnke BJ, Padilla DJ, Much TI, Poole DC (2005) Control of microvascular oxygen pressures in rat muscles comprised of different fibre types. J Physiol 563:903–913. https://doi.org/10.1113/jphysiol.2004.079533
pubmed: 15637098
pmcid: 1665627
Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301:R1078–R1087. https://doi.org/10.1152/ajpregu.00285.2011
pubmed: 21775647
Phillips SM, Green HJ, MacDonald MJ, Hughson RL (1995) Progressive effect of endurance training on [Formula: see text]̇O
pubmed: 8847253
Poole DC, Jones AM (2005) Towards an understanding of the mechanistic bases of [Formula: see text]̇O
Poole DC, Jones AM (2012) Oxygen uptake kinetics. Compr Physiol 2:933–996. https://doi.org/10.1002/cphy.c100072
pubmed: 23798293
Poole DC, Ward SA, Whipp BJ (1990) The effects of training on the metabolic and respiratory profile of high-intensity cycle ergometer exercise. Eur J Appl Physiol 59:421–429. https://doi.org/10.1007/BF02388623
Richardson RS, Noyszewski EA, Kendrick KF, Leigh JS, Wagner PD (1995) Myoglobin O
Roca J, Agusti AGN, Alonso A, Poole DC, Viegas C, Barbera JA, Rodrigez-Roisin R, Ferrer A, Wagner PD (1992) Effects of training on muscle O
pubmed: 1400019
Scalzo RL, Peltonen GL, Binns SE, Shankaran M, Giordano GR, Hartley DA, Klochak AL, Lonac MC, Paris HL, Szallar SE, Wood LM, Peelor FF 3rd, Holmes WE, Hellerstein MK, Bell C, Hamilton KL, Miller BF (2014) Greater muscle protein synthesis and mitochondrial biogenesis in males compared with females during sprint interval training. FASEB J 28:2705–2714. https://doi.org/10.1096/fj.13-246595
pubmed: 24599968
Sundberg CW, Prost RW, Fitts RH, Hunter SK (2019) Bioenergetic basis for the increased fatigability with ageing. J Physiol 597:4943–4957. https://doi.org/10.1113/JP277803
pubmed: 31018011
Suter E, Hoppeler H, Claassen H (1995) Ultrastructural modification of human skeletal-muscle tissue with 6-month moderate-intensity exercise training. Int J Sports Med 16:160–166. https://doi.org/10.1055/s-2007-972985
pubmed: 7649706
Tarnopolsky MA, Rennie CD, Robertshaw HA, Fedak-Tarnopolsky SN, Devries MC, Hamadeh MJ (2007) Influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure, substrate use, and mitochondrial enzyme activity. Am J Physiol Regul Integr Comp Physiol 292:R1271–R1278. https://doi.org/10.1152/ajpregu.00472.2006
pubmed: 17095651
Wagner PD (2006) Counterpoint: In health and in a normoxic environment, [Formula: see text]̇O
pubmed: 16468127
Whipp HB (1996) Domains of aerobic function and their limiting parameters. In: Steinacker JM, Ward SA (eds) The physiology and pathophysiology of exercise tolerance. Plenum, New York, pp 83–89
Wibom R, Hultman E, Johansson M, Matherei K, Constantin-Teodosiu D, Schantz PG (1992) Adaptation of mitochondrial ATP production in human skeletal muscle to endurance training and detraining. J Appl Physiol 73:2004–2010. https://doi.org/10.1152/jappl.1992.73.5.2004
pubmed: 1474078
Wilson JR, McCully KK, Mancini DM, Boden B, Chance B (1988) Relationship of muscular fatigue to pH and diprotonated P
pubmed: 3403417
Womack CJ, Davis SE, Blumer JL, Barrett E, Weltman AL, Gaesser GA (1995) Slow component of O
Zoladz JA, Grassi B, Majerczak J, Szkutnik Z, Korostyński M, Karasiński J, Kilarski W, Korzeniewski B (2013) Training-induced acceleration of O
pubmed: 23204290
Zoladz JA, Grassi B, Majerczak J, Szkutnik Z, Korostyński M, Grandys M, Jarmuszkiewicz W, Korzeniewski B (2014) Mechanisms responsible for the acceleration of pulmonary VO
pubmed: 25163914
Zoladz JA, Majerczak J, Galganski L, Grandys M, Zapart-Bukowska J, Kuczek P, Kołodziejski L, Walkowicz L, Szymoniak-Chochół D, Kilarski W, Jarmuszkiewicz W (2022) Endurance training increases the running performance of untrained men without changing the mitochondrial volume density in the gastrocnemius muscle. Int J Mol Sci 23:10843. https://doi.org/10.3390/ijms231810843
pubmed: 36142755
pmcid: 9503714