Central venous catheter-related infection: does insertion site still matter? A French multicentric cohort study.
Acquired infection
Bacteremia
Catheter-related infection
Central venous catheter
Colonization
Journal
Intensive care medicine
ISSN: 1432-1238
Titre abrégé: Intensive Care Med
Pays: United States
ID NLM: 7704851
Informations de publication
Date de publication:
17 Sep 2024
17 Sep 2024
Historique:
received:
12
03
2024
accepted:
15
08
2024
medline:
17
9
2024
pubmed:
17
9
2024
entrez:
17
9
2024
Statut:
aheadofprint
Résumé
We aim to evaluate the association between central venous catheter (CVC) insertion site and microbiological CVC complications in a nationwide cohort. This study was conducted using the healthcare-associated infection surveillance cohort "REA-REZO" involving 193 intensive care units (ICUs). All CVC inserted and removed during the same ICU stay between January 1st 2018 and December 31st 2022 were eligible but only those whose tips were sent for microbiological analysis were included. Primary objective was to describe CVC insertion sites and subsequent catheter-related bloodstream infection (CRBSI). Out of 126,997 CVCs, 71,314 were not sent for tip culture, and only 55,663 CVCs were included, (30,548 in internal jugular [IJ], 14,423 in femoral and 10,692 in subclavian [SC] sites). The incidence of CRBSI was 0.7 [0.6-0.8] in the IJ site, 0.7 [0.6-0.9] in the femoral site, and 0.6 [0.4-0.7] CRBSI per 1000 CVC days in the SC site (p = 0.248). The multivariable Poisson regression model showed no differences of CRBSI incidence rates between the three insertion sites. Microorganisms observed in CRBSI were coagulase-negative Staphylococci (27.9%), Enterobacterales (27.5%), non-fermenting Gram-negative Bacilli (10.4%), Candida sp. (16.9%), and Staphylococcus aureus (16.9%). Low CRBSI incidence rates were reported. CRBSI incidences rates were similar in the three insertion sites. Uncertainty remains due to potential selection bias since many CVCs had to be excluded.
Identifiants
pubmed: 39287649
doi: 10.1007/s00134-024-07615-0
pii: 10.1007/s00134-024-07615-0
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Investigateurs
Serge Alfandari
(S)
Alexandra Allaire
(A)
Antonio Alvarez
(A)
Ammenouche Nacim
(A)
Laurent Argaus
(L)
Gérard Audibert
(G)
Caroline Aurel
(C)
Odile Bajolet
(O)
Frédéric Barbut
(F)
Genevieve Barjon
(G)
Patricia Baune
(P)
Sébastien Beague
(S)
Bassam Beilouny
(B)
Nicolas Bele
(N)
Nicolas Belin
(N)
Cécile Bernerd
(C)
Yasmina Berrouane
(Y)
Aziz Berrouba
(A)
Julie Bertrand
(J)
Claire Bianchi
(C)
Sandrine Biangoma
(S)
Fabienne Birot Jaulin
(FB)
Severine Bonjean
(S)
Stéphanie Bordes-Couecou
(S)
Abdenour Bouhara
(A)
Philippe Bouillard
(P)
Céline Bourigault
(C)
Sylvie Bourzeix
(S)
Sébastien Boutreux
(S)
Hanene Bouzidi
(H)
Julie Brochart
(J)
Stéphanie Bulyez
(S)
Marie Callanquin
(M)
Nathalie Canu
(N)
Matthieu Capron
(M)
Daniel Carbognani
(D)
Vincent Castelain
(V)
Vincent Catanese
(V)
Isabelle Cattaneo
(I)
Vanessa Chartier
(V)
Guillaume Chassaing
(G)
Robert Chausset
(R)
Mélanie Chauvet
(M)
Fabrice Chopin
(F)
Catherine Chubilleau
(C)
Céline Clayer
(C)
Agnès Cohen
(A)
Sylvie Comparot
(S)
Philippe Corne
(P)
Marie-Elisabeth Cornesse
(ME)
Gaelle Corno
(G)
Esther Cortes
(E)
Patricia Courouble
(P)
Christian Crombe
(C)
Véronique Curnier
(V)
Monzer Dabbachi
(M)
Cédric Dananché
(C)
Abla Daroukh
(A)
Damien Dassant
(D)
Martine Daumas
(M)
Aurélien Daurat
(A)
Dominique Deffarges
(D)
Fanny Delanghe
(F)
Olivier Delastre
(O)
Joel Delhomme
(J)
Jean Paul Délias
(JP)
Martine Delorme
(M)
Fabienne Derramond
(F)
Frédérique Diaw
(F)
Isabelle Dijols
(I)
Kamel Djedaini
(K)
Loic Dopeux
(L)
Sophie Duhoo
(S)
Thierry Dulac
(T)
Clarisse Dupin
(C)
Laurène Dupont
(L)
Michel Durand
(M)
Isabelle Durand Joly
(ID)
Jean-Yves Dusseau
(JY)
Pierre Yves Egreteau
(PY)
Carole Eldin
(C)
Florence Espinasse
(F)
Eric Farfour
(E)
Abdelhamid Fatah
(A)
Yannick Fedun
(Y)
Luis Ferreira
(L)
Pierre Fillatre
(P)
Toufic Finge
(T)
Véronique Fleurial
(V)
Arnaud Florentin
(A)
Agnès Fribourg
(A)
Severine Gallais-Hoff
(S)
Claude Galland
(C)
Richard Galliot
(R)
Sylvain Garnier
(S)
Gaelle Gasan
(G)
Julien Gaubert-Duclos
(J)
Valérie Gauzere
(V)
Thomas Geffriaud
(T)
Isabelle Geneau
(I)
Hughes Georges
(H)
Solweig Gerbier Colomban
(SG)
Christophe Giacardi
(C)
Sebastien Gibot
(S)
Audrey Glanard
(A)
Marion Gleize
(M)
Marieline Goret
(M)
Michele Gourgues
(M)
Delphine Grau
(D)
Béatrice Grisi
(B)
Clotilde Groleau
(C)
Liliane Grolier-Bois
(L)
Catherine Guignabert
(C)
Fethi Hadj-Slimane
(F)
Emmanuelle Hammad
(E)
Catherine Haond
(C)
Marie Hélène Hausermann
(MH)
Francoise Hayo
(F)
Christophe Henry
(C)
Alexandre Herbland
(A)
Julien Huntzinger
(J)
Hervé Hyvernat
(H)
Alexandre Jean
(A)
Boris Jolibois
(B)
Sylvie Joron
(S)
Gauthier Julien
(G)
Jean Kempf
(J)
Lyes Knani
(L)
Béatrice La Combe
(B)
Marie Labruyere
(M)
Sandrine Lacroix
(S)
Bruno Lafon
(B)
Katia Lamant
(K)
Peggy Larroudé
(P)
Anne Launoy
(A)
Bernadette Laurent
(B)
Thierry Lavigne
(T)
Christine Lawrence
(C)
Quoc Vien Le
(QV)
Muriel Le Coq
(M)
Anne-Sophie Le Floch
(AS)
Fanny Le Fall
(F)
Brigitte Le Tallec
(B)
Lucie Lecoutre
(L)
Stanislas Ledochowski
(S)
Rusel Leon
(R)
Claire Lepouse
(C)
Thomas Lescot
(T)
Mélanie Levrard
(M)
Marie Laure Lier
(ML)
Anne Lignereux
(A)
Benjamin Louart
(B)
Claire Maheu
(C)
Aurélie Maindron
(A)
Francois Mallard
(F)
Marie Reine Mallaret
(MR)
Bernard Mankikian
(B)
Christiane Manzon
(C)
Philippe Mardrus
(P)
Jacques Mariot
(J)
Audry Martin
(A)
Emmanuelle Martin
(E)
Maelle Martin
(M)
Pascale Martres
(P)
Virginie Maxime
(V)
Olivier Meunier
(O)
Ella-Pauline Meyer
(EP)
Ferhat Meziani
(F)
Sébastien Moschietto
(S)
Céline Muller
(C)
Elodie Munier-Marion
(E)
Caroline Neulier
(C)
François Nicolas
(F)
Jacques-Yves Nizou
(JY)
Christine Palitta
(C)
Michel Pascal
(M)
Olivier Passouant
(O)
René-Gilles Patrigeon
(RG)
Frédérique Pavillard
(F)
Sabine Peghaire
(S)
Christophe Perdrix
(C)
Jean-Sebastien Petit
(JS)
Judith Pibre
(J)
Walter Picard
(W)
Sylvie Picault
(S)
Santiago Picos Gil
(SP)
Jérôme Pillot
(J)
Patrick Pina
(P)
Rémi Plattier
(R)
Laurent Poiron
(L)
Christian Pommier
(C)
Gaël Pradel
(G)
Cristian Prelipcean
(C)
Paul-Simon Pugliesi
(PS)
Vincent Quenee
(V)
Olga Raposo
(O)
Eve Remy
(E)
Sabine Reynaud Deforges
(SR)
Jean-Christophe Richard
(JC)
Sylvie Ricome
(S)
Thomas Rimmele
(T)
Adrien Robine
(A)
Anne-Claude Roche
(AC)
Laetitia Rohr
(L)
Gwenaël Rolland-Jacob
(G)
Adrien Roques
(A)
Catherine Rougier
(C)
Jérôme Roustan
(J)
Mélanie Saint-Leger
(M)
Faouzi Saliba
(F)
Dominique Sechaud
(D)
Amine Si-Ali
(A)
Catherine Simac
(C)
Georges Simon
(G)
Michel Sirodot
(M)
Vincent Stoeckel
(V)
Philippe Tagawa
(P)
Marine Tasle
(M)
Fabrice Thiollière
(F)
Benoit Thiphagne
(B)
Aurélie Thomas-Hervieu
(A)
François Tinturier
(F)
Alexandre Tonnelier
(A)
Alexandre Toro
(A)
David Tranvan
(D)
Dominique Trivier
(D)
Gilles Troché
(G)
Rémi Trusson
(R)
Lionel Ursulet
(L)
Marie Laure Valdeyron
(ML)
Catherine Vallet
(C)
Vanessa Van Rossem
(V)
Laurence Vasse
(L)
Myriam Venelle
(M)
Christine Venot
(C)
Antoine Vieillard-Baron
(A)
Jean-François Vincent
(JF)
Michel Vitris
(M)
Hussein Yassine
(H)
Lassane Zanre
(L)
Cecile Zylberfajn
(C)
Informations de copyright
© 2024. Springer-Verlag GmbH Germany, part of Springer Nature.
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