NOS3
PAI‐1
Serpine1
metabolic reprogramming
pulmonary hypertension
thrombosis
vascular remodeling
Journal
Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524
Informations de publication
Date de publication:
18 Sep 2024
18 Sep 2024
Historique:
medline:
18
9
2024
pubmed:
18
9
2024
entrez:
18
9
2024
Statut:
aheadofprint
Résumé
G6PD (glucose-6-phosphate-dehydrogenase) is a key enzyme in the glycolytic pathway and has been implicated in the pathogenesis of cancer and pulmonary hypertension-associated vascular remodeling. Here, we investigated the role of an X-linked CRISPR-Cas9 genome editing was used to generate the Our results suggest G6PD
Sections du résumé
BACKGROUND
BACKGROUND
G6PD (glucose-6-phosphate-dehydrogenase) is a key enzyme in the glycolytic pathway and has been implicated in the pathogenesis of cancer and pulmonary hypertension-associated vascular remodeling. Here, we investigated the role of an X-linked
METHODS AND RESULTS
RESULTS
CRISPR-Cas9 genome editing was used to generate the
CONCLUSIONS
CONCLUSIONS
Our results suggest G6PD
Identifiants
pubmed: 39291493
doi: 10.1161/JAHA.123.035174
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM