Preschool-age children maintain a distinct memory CD4
Humans
COVID-19
/ immunology
Child, Preschool
SARS-CoV-2
/ immunology
CD4-Positive T-Lymphocytes
/ immunology
Adult
Memory B Cells
/ immunology
Child
Memory T Cells
/ immunology
Male
Immunologic Memory
Female
Antibodies, Viral
/ immunology
Middle Aged
Antibodies, Neutralizing
/ immunology
Young Adult
Journal
Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086
Informations de publication
Date de publication:
18 Sep 2024
18 Sep 2024
Historique:
medline:
18
9
2024
pubmed:
18
9
2024
entrez:
18
9
2024
Statut:
ppublish
Résumé
The development of the human immune system lasts for several years after birth. The impact of this maturation phase on the quality of adaptive immunity and the acquisition of immunological memory after infection at a young age remains incompletely defined. Here, using an antigen-reactive T cell (ARTE) assay and multidimensional flow cytometry, we profiled circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-reactive CD3
Identifiants
pubmed: 39292802
doi: 10.1126/scitranslmed.adl1997
doi:
Substances chimiques
Antibodies, Viral
0
Antibodies, Neutralizing
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM