Quantitation of mitral regurgitation using positron emission tomography.
Cardiac PET
Cardiovascular MRI
Cardiovascular diseases
Mitral regurgitation
Quantitation
Journal
EJNMMI research
ISSN: 2191-219X
Titre abrégé: EJNMMI Res
Pays: Germany
ID NLM: 101560946
Informations de publication
Date de publication:
18 Sep 2024
18 Sep 2024
Historique:
received:
14
06
2024
accepted:
09
09
2024
medline:
19
9
2024
pubmed:
19
9
2024
entrez:
18
9
2024
Statut:
epublish
Résumé
Cardiac positron emission tomography (PET) offers non-invasive assessment of perfusion and left ventricular (LV) function from a single dynamic scan. However, no prior assessment of mitral regurgitation severity by PET has been presented. Application of indicator dilution techniques and gated image analyses to PET data enables calculation of forward stroke volume and total LV stroke volume. We aimed to evaluate a combination of these methods for measurement of regurgitant volume (RegVol) and fraction (RegF) using dynamic Twenty-one patients with severe primary mitral valve regurgitation underwent same-day dynamic PET examinations ( LV regurgitation severity quantified using cardiac PET correlated with CMR and showed high accuracy for discriminating patients from healthy volunteers.
Sections du résumé
BACKGROUND
BACKGROUND
Cardiac positron emission tomography (PET) offers non-invasive assessment of perfusion and left ventricular (LV) function from a single dynamic scan. However, no prior assessment of mitral regurgitation severity by PET has been presented. Application of indicator dilution techniques and gated image analyses to PET data enables calculation of forward stroke volume and total LV stroke volume. We aimed to evaluate a combination of these methods for measurement of regurgitant volume (RegVol) and fraction (RegF) using dynamic
RESULTS
RESULTS
Twenty-one patients with severe primary mitral valve regurgitation underwent same-day dynamic PET examinations (
CONCLUSIONS
CONCLUSIONS
LV regurgitation severity quantified using cardiac PET correlated with CMR and showed high accuracy for discriminating patients from healthy volunteers.
Identifiants
pubmed: 39294533
doi: 10.1186/s13550-024-01150-1
pii: 10.1186/s13550-024-01150-1
doi:
Types de publication
Journal Article
Langues
eng
Pagination
85Informations de copyright
© 2024. The Author(s).
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