Current and emerging technologies to develop Point-of-Care Diagnostics in medical mycology.

Aspergillus Cryptococcus Point–of–Care Diagnostics endemic fungal infections fungal infections lateral flow assay

Journal

Expert review of molecular diagnostics
ISSN: 1744-8352
Titre abrégé: Expert Rev Mol Diagn
Pays: England
ID NLM: 101120777

Informations de publication

Date de publication:
18 Sep 2024
Historique:
medline: 19 9 2024
pubmed: 19 9 2024
entrez: 19 9 2024
Statut: aheadofprint

Résumé

Advances in diagnostic technologies, particularly Point-of-Care Diagnostics (POCDs), have revolutionized clinical practice by providing rapid, user-friendly, and affordable testing at or near the patient's location. POCDs have been increasingly introduced in medical mycology and hold promise to improve patient outcomes in a variety of important human fungal diseases. This review focuses on validated POCDs, particularly lateral flow assays (LFAs), for various fungal diseases. Additionally, we discuss emerging innovative techniques such as body fluid analysis, imaging methods, loop-mediated isothermal amplification (LAMP), microfluidic systems, clustered regularly interspaced short palindromic repeats (CRISPR)-based diagnostics, and the emerging role of artificial intelligence. Compact and user-friendly POCDs have been increasingly introduced in medical mycology, and some of these tests (e.g.

Identifiants

pubmed: 39294931
doi: 10.1080/14737159.2024.2397515
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-18

Auteurs

Takahiro Matsuo (T)

Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Sebastian Wurster (S)

Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Martin Hoenigl (M)

Division of Infectious Diseases, ECMM Excellence Center, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Translational Medical Mycology Research Group, Medical University of Graz, Graz, Austria.
Bio TechMed, Graz, Austria.

Dimitrios P Kontoyiannis (DP)

Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Classifications MeSH