Child Neurology: Remarkable Recovery From Severe Acute Necrotizing Encephalopathy.


Journal

Neurology
ISSN: 1526-632X
Titre abrégé: Neurology
Pays: United States
ID NLM: 0401060

Informations de publication

Date de publication:
22 Oct 2024
Historique:
medline: 20 9 2024
pubmed: 20 9 2024
entrez: 19 9 2024
Statut: ppublish

Résumé

A previously healthy 6-year-old girl presented with several days of fever before a generalized seizure. Laboratory investigation revealed elevated liver enzymes, normal ammonia, and positive influenza A through respiratory PCR. Brain MRI demonstrated extensive, bilateral lesions in the cerebral and cerebellar white matter, thalami, basal ganglia, and brainstem. She was diagnosed with acute necrotizing encephalopathy, a rare parainfectious encephalitis commonly associated with influenza. Genetic variants have been implicated (e.g.,

Identifiants

pubmed: 39298704
doi: 10.1212/WNL.0000000000209877
doi:

Types de publication

Journal Article Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

e209877

Auteurs

Andrew Silverman (A)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

Matthew Sasaki (M)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

José Eduardo Espíndola Lima (JE)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

Chrisoula Cheronis (C)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

Grant L Lin (GL)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

Alexandra Johnson (A)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

Hisham Dahmoush (H)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

Eva Archer (E)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

Karolina Grekov (K)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

Thomas J LaRocca (TJ)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

Keith Van Haren (K)

From the Child Neurology Division (A.S., M.S., J.E.E.L., C.C., G.L.L., A.J., K.V.H.), Department of Neurology, Pediatric Neuroradiology (H.D.), Department of Radiology, Infectious Disease Division (E.A.), and Critical Care Medicine (K.G., T.J.L.), Department of Pediatrics, and Neuroimmunology Division (K.V.H.), Department of Neurology, Stanford Medicine, Palo Alto, CA.

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