Suicidality among clients in a network of coordinated specialty care (CSC) programs for first-episode psychosis: Rates, changes in rates, and their predictors.

Early psychosis Schizophrenia Services Suicide

Journal

Schizophrenia research
ISSN: 1573-2509
Titre abrégé: Schizophr Res
Pays: Netherlands
ID NLM: 8804207

Informations de publication

Date de publication:
18 Sep 2024
Historique:
received: 26 02 2024
revised: 10 07 2024
accepted: 26 07 2024
medline: 19 9 2024
pubmed: 19 9 2024
entrez: 19 9 2024
Statut: aheadofprint

Résumé

People experiencing their first episode of psychosis have high risk of suicide, and programs specializing in early psychosis have not always achieved reduced risk. The present study analyzes patterns of suicide ideation, self-harm, and suicide attempts within the Connection Learning Healthcare System of 23 early psychosis programs in Pennsylvania and Maryland that follow the Coordinated Specialty Care treatment model. People with first episode psychosis (n = 1101) were assessed at admission and every six months using a standardized battery that included self-reported past-month ideation and clinician-reported past-six-month ideation, self-harm, and suicide attempts. At admission, there were 28 % rates of self-reported past-month suicide ideation and 52 % rates clinician-reported past-six-month suicide ideation, 23 % rate of clinician-reported self-harm, and 15 % rate of attempts. After the first six months of treatment there were significantly lower rates of clinician-reported suicidality (with reductions of at least 77 %), and after the first year of treatment there was significantly lower self-reported ideation (with approximately 54 % reporting lower past-month ideation). Changes were not accounted for by differential early discharge. A range of psychosocial variables predicted within- and between-subject variability in suicidality. Social and role functioning, depressive symptom severity, and a sense of recovery were significant within-subject predictors of all four measures of suicidality. Compared to admission, we observed substantially lower rates of suicidality within the first year of treatment for clients with first episode psychosis in Coordinated Specialty Care. Reductions were predicted by some of the variables targeted by the treatment model.

Sections du résumé

BACKGROUND BACKGROUND
People experiencing their first episode of psychosis have high risk of suicide, and programs specializing in early psychosis have not always achieved reduced risk. The present study analyzes patterns of suicide ideation, self-harm, and suicide attempts within the Connection Learning Healthcare System of 23 early psychosis programs in Pennsylvania and Maryland that follow the Coordinated Specialty Care treatment model.
METHOD METHODS
People with first episode psychosis (n = 1101) were assessed at admission and every six months using a standardized battery that included self-reported past-month ideation and clinician-reported past-six-month ideation, self-harm, and suicide attempts.
RESULTS RESULTS
At admission, there were 28 % rates of self-reported past-month suicide ideation and 52 % rates clinician-reported past-six-month suicide ideation, 23 % rate of clinician-reported self-harm, and 15 % rate of attempts. After the first six months of treatment there were significantly lower rates of clinician-reported suicidality (with reductions of at least 77 %), and after the first year of treatment there was significantly lower self-reported ideation (with approximately 54 % reporting lower past-month ideation). Changes were not accounted for by differential early discharge. A range of psychosocial variables predicted within- and between-subject variability in suicidality. Social and role functioning, depressive symptom severity, and a sense of recovery were significant within-subject predictors of all four measures of suicidality.
CONCLUSIONS CONCLUSIONS
Compared to admission, we observed substantially lower rates of suicidality within the first year of treatment for clients with first episode psychosis in Coordinated Specialty Care. Reductions were predicted by some of the variables targeted by the treatment model.

Identifiants

pubmed: 39298811
pii: S0920-9964(24)00360-8
doi: 10.1016/j.schres.2024.07.054
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

150-157

Informations de copyright

Copyright © 2024 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest Robert W. Buchanan has consulted for Boehringer-Ingelheim; serves on the Data Safety and Monitoring Boards of Roche, Merck and Newron; and has served on the Advisory Boards of Merck, Acadia, Karuna, and Neurocrine. All other authors have no declarations.

Auteurs

Peter Phalen (P)

Division of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: pphalen@som.umaryland.edu.

Nev Jones (N)

School of Social Work, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Beshaun Davis (B)

National Institute of Mental Health, Bethesda, MD, USA.

Deepak Sarpal (D)

School of Social Work, University of Pittsburgh, Pittsburgh, PA, USA.

Faith Dickerson (F)

Department of Psychology, Sheppard Pratt, Baltimore, MD, USA.

Crystal Vatza (C)

Department of Psychology, Sheppard Pratt, Baltimore, MD, USA.

Megan Jumper (M)

Neurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Adam Kuczynski (A)

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA.

Elizabeth Thompson (E)

Alpert Medical School, Brown University, USA.

Samantha Jay (S)

University of Maryland Baltimore County, Baltimore, MD, USA.

Robert Buchanan (R)

Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.

K N R Chengappa (KNR)

School of Social Work, University of Pittsburgh, Pittsburgh, PA, USA.

Richard Goldberg (R)

Division of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.

Julie Kreyenbuhl (J)

Division of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.

Russell Margolis (R)

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Fanghong Dong (F)

Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.

Jessie Riggs (J)

Neurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Alex Moxam (A)

Neurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, USA.

Elizabeth Burris (E)

Wesley Family Services First Episode Psychosis Program-ENGAGE, USA.

Philip Campbell (P)

Neurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Akinyi Cooke (A)

Johns Hopkins Bayview Medical Center Community Psychiatry Program, Baltimore, MD, USA.

Arielle Ered (A)

Neurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Mandy Fauble (M)

UPMC Western Behavioral Health at Safe Harbor, Erie, PA, USA.

Carolyn Howell (C)

Johns Hopkins Bayview Medical Center Community Psychiatry Program, Baltimore, MD, USA.

Christian Kelly (C)

University of Pittsburgh Medical Center, Western Psychiatric Hospital, Pittsburgh, PA, USA.

Denise Namowicz (D)

Children's Services Center, Wilkes Barre, PA, USA.

Krissa Rouse (K)

First Episode Clinic/Maryland Psychiatric Research Center, University of Maryland School of Medicine, Catonsville, MD, USA.

William Smith (W)

Neurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Max Wolcott (M)

Johns Hopkins Bayview Medical Center Community Psychiatry Program, Baltimore, MD, USA.

Yasmine Boumaiz (Y)

Division of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.

Alexander Harvin (A)

Department of Psychology, Sheppard Pratt, Baltimore, MD, USA.

R Scheinberg (R)

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Arunadevi Saravana (A)

Division of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.

Swati Nayar (S)

Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Christian Kohler (C)

Neurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Monica E Calkins (ME)

Neurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Melanie Bennett (M)

Division of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.

Classifications MeSH