Sex dependent effects of cardiovascular agents on hemoglobin oxygen affinity - An ex-vivo experiment.
Catecholamines
Half saturation pressure
Inotropics
Oxygen dissociation curve
Journal
Journal of critical care
ISSN: 1557-8615
Titre abrégé: J Crit Care
Pays: United States
ID NLM: 8610642
Informations de publication
Date de publication:
18 Sep 2024
18 Sep 2024
Historique:
received:
14
11
2023
revised:
27
08
2024
accepted:
05
09
2024
medline:
20
9
2024
pubmed:
20
9
2024
entrez:
19
9
2024
Statut:
aheadofprint
Résumé
Hemoglobin‑oxygen (Hb-O In this experimental ex-vivo trial, venous blood samples were taken from 5 male and 6 female volunteers and incubated with the particular cardiovascular agents. Oxygen dissociation curves (ODC) were measured in-vitro with a new high-throughput method. Compared to the P All investigated agents decreased Hb-O
Sections du résumé
BACKGROUND
BACKGROUND
Hemoglobin‑oxygen (Hb-O
METHODS
METHODS
In this experimental ex-vivo trial, venous blood samples were taken from 5 male and 6 female volunteers and incubated with the particular cardiovascular agents. Oxygen dissociation curves (ODC) were measured in-vitro with a new high-throughput method.
RESULTS
RESULTS
Compared to the P
DISCUSSION
CONCLUSIONS
All investigated agents decreased Hb-O
Identifiants
pubmed: 39299023
pii: S0883-9441(24)00403-9
doi: 10.1016/j.jcrc.2024.154916
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
154916Informations de copyright
Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.