Predictive Hypoxemic Threshold for Tolerating the Apnea Test While Assessing Death by Neurological Criteria.
Brain death
Organ donation
Journal
Neurocritical care
ISSN: 1556-0961
Titre abrégé: Neurocrit Care
Pays: United States
ID NLM: 101156086
Informations de publication
Date de publication:
19 Sep 2024
19 Sep 2024
Historique:
received:
30
03
2024
accepted:
13
08
2024
medline:
20
9
2024
pubmed:
20
9
2024
entrez:
19
9
2024
Statut:
aheadofprint
Résumé
The apnea test (AT) plays a vital role in diagnosing brain death by evaluating the absence of spontaneous respiratory activity. It entails disconnecting the patient from mechanical ventilation to raise the CO We conducted a retrospective cohort study involving patients suspected of having brain death at the Tel Aviv Medical Center from 2010 to 2022. The primary outcome was defined as an arterial partial O Among the 70 patients who underwent AT, 7 patients met the primary diagnostic criteria. Patients with a PaO PaO
Sections du résumé
BACKGROUND
BACKGROUND
The apnea test (AT) plays a vital role in diagnosing brain death by evaluating the absence of spontaneous respiratory activity. It entails disconnecting the patient from mechanical ventilation to raise the CO
METHODS
METHODS
We conducted a retrospective cohort study involving patients suspected of having brain death at the Tel Aviv Medical Center from 2010 to 2022. The primary outcome was defined as an arterial partial O
RESULTS
RESULTS
Among the 70 patients who underwent AT, 7 patients met the primary diagnostic criteria. Patients with a PaO
CONCLUSIONS
CONCLUSIONS
PaO
Identifiants
pubmed: 39300039
doi: 10.1007/s12028-024-02105-z
pii: 10.1007/s12028-024-02105-z
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s).
Références
De Georgia MA. History of brain death as death: 1968 to the present. J Crit Care. 2014;29:673–8.
doi: 10.1016/j.jcrc.2014.04.015
pubmed: 24930367
Shewmon DA, Sylmar CA, Verheijde JL, Rady MY. Evidence-based guideline update: determining brain death in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2011;76(3):308.
pubmed: 21302378
Greer DM, Kirschen MP, Lewis A, Gronseth GS, Rae-Grant A, Ashwal S, et al. Pediatric and adult brain death/death by neurologic criteria consensus guideline. Neurology. 2023. https://doi.org/10.1212/WNL.0000000000207740 .
doi: 10.1212/WNL.0000000000207740
pubmed: 37829552
pmcid: 10401682
Wijdicks EFM, Varelas PN, Gronseth GS, Greer DM. Evidence-based guideline update: determining brain death in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2010;74:1911–8.
doi: 10.1212/WNL.0b013e3181e242a8
pubmed: 20530327
Truog RD, Robinson WM. Role of brain death and the dead-donor rule in the ethics of organ transplantation. Crit Care Med. 2003;31:2391–6.
doi: 10.1097/01.CCM.0000090869.19410.3C
pubmed: 14501972
Lewis A, Kirschen MP, Greer D. The 2023 AAN/AAP/CNS/SCCM pediatric and adult brain death/death by neurologic criteria consensus practice guideline: a comparison with the 2010 and 2011 guidelines. Neurol Clin Pract. 2023;13: e200189.
doi: 10.1212/CPJ.0000000000200189
pubmed: 37829552
Greer DM, Shemie SD, Lewis A, Torrance S, Varelas P, Goldenberg FD, et al. Determination of brain death/death by neurologic criteria: the World Brain Death Project. JAMA. 2020;324:1078–97.
doi: 10.1001/jama.2020.11586
pubmed: 32761206
Spinello IM. Brain death determination. J Intensive Care Med. 2015;30:326–37.
doi: 10.1177/0885066613511053
pubmed: 24227449
Sveen WN, Antommaria AHM, Gilene SJ, Stalets EL. Adverse events during apnea testing for the determination of death by neurologic criteria: a single-center, retrospective pediatric cohort. Pediatr Crit Care Med. 2023;24:399–405.
doi: 10.1097/PCC.0000000000003198
pubmed: 36815829
Sayan HE. Retrospective analysis of the apnea test and ancillary test in determining brain death. Rev Bras Ter Intensiva. 2020;32:405–11.
doi: 10.5935/0103-507X.20200069
pubmed: 33053030
pmcid: 7595719
Busl KM, Lewis A, Varelas PN. Apnea testing for the determination of brain death: a systematic scoping review. Neurocrit Care. 2021;34:608–20.
doi: 10.1007/s12028-020-01015-0
pubmed: 32524528
Yee AH, Mandrekar J, Rabinstein AA, Wijdicks EFM. Predictors of apnea test failure during brain death determination. Neurocrit Care. 2010;12:352–5.
doi: 10.1007/s12028-010-9343-4
pubmed: 20217276
Kim JJ, Kim EY. Identification of hemodynamic risk factors for apnea test failure during brain death determination. Transplant Proc. 2019;51:1655–60.
doi: 10.1016/j.transproceed.2019.04.029
pubmed: 31255358