Human TDP43 is required for ALS‑related annexin A11 toxicity in

Drosophila TDP43 amyotrophic lateral sclerosis annexin A11 neurodegeneration

Journal

Biomedical reports
ISSN: 2049-9442
Titre abrégé: Biomed Rep
Pays: England
ID NLM: 101613227

Informations de publication

Date de publication:
Nov 2024
Historique:
received: 16 01 2024
accepted: 13 06 2024
medline: 20 9 2024
pubmed: 20 9 2024
entrez: 20 9 2024
Statut: epublish

Résumé

Genomics allows identification of genes and mutations associated with amyotrophic lateral sclerosis (ALS). Mutations in annexin A11 (ANXA11) are responsible for ~1% of all familial ALS and fronto-temporal dementia cases. The present study used the fruit fly,

Identifiants

DOI: 10.3892/br.2024.1853 PMID: 39301564 PMC: PMC11411402
pubmed: 39301564
doi: 10.3892/br.2024.1853
pii: BR-21-5-01853
pmc: PMC11411402
doi:

Types de publication

Journal Article

Langues

eng

Pagination

165

Informations de copyright

Copyright: © 2024 Barnard et al.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests.

Auteurs

Jodi Barnard (J)

Department of Basic and Clinical Neuroscience, Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9NU, UK.

Rachel Hunt (R)

Department of Basic and Clinical Neuroscience, Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9NU, UK.

Mert Yucel (M)

Department of Basic and Clinical Neuroscience, Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9NU, UK.

David Mazaud (D)

Department of Basic and Clinical Neuroscience, Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9NU, UK.

Bradley N Smith (BN)

Department of Basic and Clinical Neuroscience, Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9NU, UK.
Centre for Developmental Neurobiology and Medical Research Council Centre for Neurodevelopmental Disorders, Institute of Psychiatry, Psychology and Neuroscience, Guy's Campus, King's College London, London SE1 1UL, UK.

Manolis Fanto (M)

Department of Basic and Clinical Neuroscience, Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9NU, UK.

Classifications MeSH