Fermented Dairy Products, Musculoskeletal and Mental Health in Older Adults: is There Evidence to Support Benefits that go Beyond Those of Non-Fermented Dairy Products?
Cognition
Fermented dairy products
Fractures
Mental health
Osteoporosis
Sarcopenia
Journal
Calcified tissue international
ISSN: 1432-0827
Titre abrégé: Calcif Tissue Int
Pays: United States
ID NLM: 7905481
Informations de publication
Date de publication:
20 Sep 2024
20 Sep 2024
Historique:
received:
22
03
2024
accepted:
11
09
2024
medline:
20
9
2024
pubmed:
20
9
2024
entrez:
20
9
2024
Statut:
aheadofprint
Résumé
Fermented dairy products have recently gained popularity due to their purported health benefits, nevertheless, their role in ageing remains uncertain. This narrative review aims to evaluate evidence from observational (prospective) and interventional studies on the potential benefits of fermented dairy product consumption for musculoskeletal and mental health in older adults. Additionally, it seeks to determine whether any observed benefits surpass those of non-fermented dairy products and to identify directions for future research. Prospective studies support either favourable or neutral associations of fermented dairy products with outcomes of musculoskeletal health or neutral associations with mental health outcomes, whilst it remains unclear if the benefits observed with fermented dairy products go beyond those of the non-fermented dairy foods. Few interventional studies suggest overall favourable effects of yogurt and cheese on musculoskeletal health in older adults but given their small number (N = 6) and heterogeneity, they do not allow a clear assessment or definitive recommendations for fermented dairy intake. Interventional studies reporting mental health outcomes are largely lacking for this age group (N = 1). Given the very limited evidence for the effectiveness of fermented dairy products, future well-designed prospective and randomized controlled trials are needed to better understand their benefits (especially compared to those of non-fermented dairy foods), their characteristics and the quantities required to offer protection against musculoskeletal and/or mental health ageing.
Identifiants
pubmed: 39302464
doi: 10.1007/s00223-024-01291-4
pii: 10.1007/s00223-024-01291-4
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s).
Références
Yannakoulia M, Mamalaki E, Anastasiou CA, Mourtzi N, Lambrinoudaki I, Scarmeas N (2018) Eating habits and behaviors of older people: where are we now and where should we go? Maturitas 114:14–21. https://doi.org/10.1016/j.maturitas.2018.05.001
doi: 10.1016/j.maturitas.2018.05.001
pubmed: 29907241
Kiefte-de Jong JC, Mathers JC, Franco OH (2014) Nutrition and healthy ageing: the key ingredients. Proc Nutr Soc 73:249–259. https://doi.org/10.1017/S0029665113003881
doi: 10.1017/S0029665113003881
pubmed: 24503212
Dimidi E, Cox SR, Rossi M, Whelan K (2019) Fermented foods: definitions and characteristics, impact on the gut microbiota and effects on gastrointestinal health and disease. Nutrients 11:1806. https://doi.org/10.3390/nu11081806
doi: 10.3390/nu11081806
pubmed: 31387262
pmcid: 6723656
Marco ML, Sanders ME, Gänzle M, Arrieta MC, Cotter PD, De Vuyst L, Hill C, Holzapfel W, Lebeer S, Merenstein D, Reid G, Wolfe BE, Hutkins R (2021) The international scientific association for probiotics and prebiotics (ISAPP) consensus statement on fermented foods. Nat Rev Gastroenterol Hepatol 18:196–208. https://doi.org/10.1038/s41575-020-00390-5
doi: 10.1038/s41575-020-00390-5
pubmed: 33398112
pmcid: 7925329
Li KJ, Burton-Pimentel KJ, Vergères G, Feskens EJM, Brouwer-Brolsma EM (2022) Fermented foods and cardiometabolic health: definitions, current evidence, and future perspectives. Front Nutr 9:976020. https://doi.org/10.3389/fnut.2022.976020
doi: 10.3389/fnut.2022.976020
pubmed: 36204374
pmcid: 9530890
Marco ML, Heeney D, Binda S, Cifelli CJ, Cotter PD, Foligné B, Gänzle M, Kort R, Pasin G, Pihlanto A, Smid EJ, Hutkins R (2017) Health benefits of fermented foods: microbiota and beyond. Curr Opin Biotechnol 44:94–102. https://doi.org/10.1016/j.copbio.2016.11.010
doi: 10.1016/j.copbio.2016.11.010
pubmed: 27998788
Kok CR, Hutkins R (2018) Yogurt and other fermented foods as sources of health-promoting bacteria. Nutr Rev 76:4–15. https://doi.org/10.1093/nutrit/nuy056
doi: 10.1093/nutrit/nuy056
pubmed: 30452699
Savaiano DA, Hutkins RW (2021) Yogurt, cultured fermented milk, and health: a systematic review. Nutr Rev 79:599–614. https://doi.org/10.1093/nutrit/nuaa013
doi: 10.1093/nutrit/nuaa013
pubmed: 32447398
Cuesta-Triana F, Verdejo-Bravo C, Fernández-Pérez C, Martín-Sánchez FJ (2019) Effect of milk and other dairy products on the risk of frailty, sarcopenia, and cognitive performance decline in the elderly: a systematic review. Adv Nutr 10:S105–S119. https://doi.org/10.1093/advances/nmy105
doi: 10.1093/advances/nmy105
pubmed: 31089731
pmcid: 6518150
Rozenberg S, Body JJ, Bruyère O, Bergmann P, Brandi ML, Cooper C, Devogelaer JP, Gielen E, Goemaere S, Kaufman JM, Rizzoli R, Reginster JY (2016) Effects of dairy products consumption on health: benefits and beliefs—a commentary from the Belgian Bone Club and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases. Calcif Tissue Int 98:1–17. https://doi.org/10.1007/s00223-015-0062-x
doi: 10.1007/s00223-015-0062-x
pubmed: 26445771
Bian S, Hu J, Zhang K, Wang Y, Yu M, Ma J (2018) Dairy product consumption and risk of hip fracture: a systematic review and meta-analysis. BMC Public Health 18:165. https://doi.org/10.1186/s12889-018-5041-5
doi: 10.1186/s12889-018-5041-5
pubmed: 29357845
pmcid: 5778815
Ong AM, Kang K, Weiler HA, Morin SN (2020) Fermented milk products and bone health in postmenopausal women: a systematic review of randomized controlled trials, prospective cohorts, and case-control studies. Adv Nutr 11:251–265. https://doi.org/10.1093/advances/nmz108
doi: 10.1093/advances/nmz108
pubmed: 31603185
Rizzoli R, Biver E, Brennan-Speranza TC (2021) Nutritional intake and bone health. Lancet Diabetes Endocrinol 9:606–621. https://doi.org/10.1016/S2213-8587(21)00119-4
doi: 10.1016/S2213-8587(21)00119-4
pubmed: 34242583
Rizzoli R, Biver E (2018) Effects of fermented milk products on bone. Calcif Tissue Int 102:489–500. https://doi.org/10.1007/s00223-017-0317-9
doi: 10.1007/s00223-017-0317-9
pubmed: 28823001
Rizzoli R, Biver E, Bonjour JP, Coxam V, Goltzman D, Kanis JA, Lappe J, Rejnmark L, Sahni S, Weaver C, Weiler H, Reginster JY (2018) Benefits and safety of dietary protein for bone health-an expert consensus paper endorsed by the European Society for Clinical and Economical Aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation. Osteoporos Int 29:1933–1948. https://doi.org/10.1007/s00198-018-4534-5
doi: 10.1007/s00198-018-4534-5
pubmed: 29740667
Cunningham C, O’Sullivan R, Caserotti P, Tully MA (2020) Consequences of physical inactivity in older adults: a systematic review of reviews and meta-analyses. Scand J Med Sci Sports 30:816–27. https://doi.org/10.1111/sms.13616
doi: 10.1111/sms.13616
pubmed: 32020713
Alvarez-Nuncio MDC, Ziegler TR (2024) Micronutrient status and protein-energy malnutrition in free-living older adults: a current perspective. Curr Opin Gastroenterol 40:99–105. https://doi.org/10.1097/MOG.0000000000001000
doi: 10.1097/MOG.0000000000001000
pubmed: 38193299
Davies LE, Spiers G, Kingston A, Todd A, Adamson J, Hanratty B (2020) Adverse outcomes of polypharmacy in older people: systematic review of reviews. J Am Med Dir Assoc 21:181–187. https://doi.org/10.1016/j.jamda.2019.10.022
doi: 10.1016/j.jamda.2019.10.022
pubmed: 31926797
Chollet M, Gille D, Piccinali P, Bütikofer U, Schmid A, Stoffers H, Altintzoglou T, Walther B (2014) Short communication: dairy consumption among middle-aged and elderly adults in Switzerland. J Dairy Sci 97:5387–5392. https://doi.org/10.3168/jds.2014-8193
doi: 10.3168/jds.2014-8193
pubmed: 24997665
Autio M, Sekki S, Autio J, Peltonen K, Niva M (2023) Towards de-dairyfication of the diet? Consumers downshifting milk, yet justifying their dairy pleasures. Front Sustain 4:975679. https://doi.org/10.3389/frsus.2023.975679
doi: 10.3389/frsus.2023.975679
Ano Y, Nakayama H (2018) Preventive effects of dairy products on dementia and the underlying mechanisms. Int J Mol Sci 19:1927. https://doi.org/10.3390/ijms19071927
doi: 10.3390/ijms19071927
pubmed: 29966358
pmcid: 6073537
Feart C, Lorrain S, Ginder Coupez V, Samieri C, Letenneur L, Paineau D, Barberger-Gateau P (2013) Adherence to a Mediterranean diet and risk of fractures in French older persons. Osteoporos Int 24:3031–3041. https://doi.org/10.1007/s00198-013-2421-7
doi: 10.1007/s00198-013-2421-7
pubmed: 23783645
Michaëlsson K, Wolk A, Langenskiöld S, Basu S, Warensjö Lemming E, Melhus H, Byberg L (2014) Milk intake and risk of mortality and fractures in women and men: cohort studies. BMJ 349:g6015. https://doi.org/10.1136/bmj.g6015
doi: 10.1136/bmj.g6015
pubmed: 25352269
pmcid: 4212225
Sahni S, Mangano KM, Tucker KL, Kiel DP, Casey VA, Hannan MT (2014) Protective association of milk intake on the risk of hip fracture: results from the Framingham Original Cohort. J Bone Miner Res 29:1756–1762. https://doi.org/10.1002/jbmr.2219
doi: 10.1002/jbmr.2219
pubmed: 24760749
Feskanich D, Meyer HE, Fung TT, Bischoff-Ferrari HA, Willett WC (2018) Milk and other dairy foods and risk of hip fracture in men and women. Osteoporos Int 29:385–396. https://doi.org/10.1007/s00198-017-4285-8
doi: 10.1007/s00198-017-4285-8
pubmed: 29075804
Michaëlsson K, Wolk A, Lemming EW, Melhus H, Byberg L (2018) Intake of milk or fermented milk combined with fruit and vegetable consumption in relation to hip fracture rates: a cohort study of Swedish women. J Bone Miner Res 33:449–457. https://doi.org/10.1002/jbmr.3324
doi: 10.1002/jbmr.3324
pubmed: 29083056
Machado-Fragua MD, Struijk EA, Caballero FF, Ortolá R, Lana A, Banegas JR, Rodríguez-Artalejo F, Lopez-Garcia E (2020) Dairy consumption and risk of falls in 2 European cohorts of older adults. Clin Nutr 39:3140–3146. https://doi.org/10.1016/j.clnu.2020.01.025
doi: 10.1016/j.clnu.2020.01.025
pubmed: 32075745
Sing CW, Lin TC, Bartholomew S, Bell JS, Bennett C, Beyene K, Bosco-Levy P, Bradbury BD, Chan AHY, Chandran M, Cooper C, de Ridder M, Doyon CY, Droz-Perroteau C, Ganesan G, Hartikainen S, Ilomaki J, Jeong HE, Kiel DP, Kubota K, Lai EC, Lange JL, Lewiecki EM, Lin J, Liu J, Maskell J, de Abreu MM, O’Kelly J, Ooba N, Pedersen AB, Prats-Uribe A, Prieto-Alhambra D, Qin SX, Shin JY, Sørensen HT, Tan KB, Thomas T, Tolppanen AM, Verhamme KMC, Wang GH, Watcharathanakij S, Wood SJ, Cheung CL, Wong ICK (2023) Global epidemiology of hip fractures: secular trends in incidence rate, post-fracture treatment, and all-cause mortality. J Bone Miner Res 38:1064–1075. https://doi.org/10.1002/jbmr.4821
doi: 10.1002/jbmr.4821
pubmed: 37118993
Downey C, Kelly M, Quinlan JF (2019) Changing trends in the mortality rate at 1-year post hip fracture - a systematic review. World J Orthop 10:166–175. https://doi.org/10.5312/wjo.v10.i3.166
doi: 10.5312/wjo.v10.i3.166
pubmed: 30918799
pmcid: 6428998
Lewis JR, Voortman T, Ioannidis JP (2021) Evaluating and strengthening the evidence for nutritional bone research: ready to break new ground? J Bone Miner Res 36:219–226. https://doi.org/10.1002/jbmr.4236
doi: 10.1002/jbmr.4236
pubmed: 33503301
Sahni S, Mangano KM, Kiel DP, Tucker KL, Hannan MT (2017) Dairy intake is protective against bone loss in older vitamin d supplement users: the Framingham Study. J Nutr 147:645–652. https://doi.org/10.3945/jn.116.240390
doi: 10.3945/jn.116.240390
pubmed: 28250192
pmcid: 5368576
Biver E, Durosier-Izart C, Merminod F, Chevalley T, van Rietbergen B, Ferrari SL, Rizzoli R (2018) Fermented dairy products consumption is associated with attenuated cortical bone loss independently of total calcium, protein, and energy intakes in healthy postmenopausal women. Osteoporos Int 29:1771–1782. https://doi.org/10.1007/s00198-018-4535-4
doi: 10.1007/s00198-018-4535-4
pubmed: 29725715
Vercambre MN, Boutron-Ruault MC, Ritchie K, Clavel-Chapelon F, Berr C (2009) Long-term association of food and nutrient intakes with cognitive and functional decline: a 13-year follow-up study of elderly French women. Br J Nutr 102:419–427. https://doi.org/10.1017/S0007114508201959
doi: 10.1017/S0007114508201959
pubmed: 19203415
pmcid: 2891709
Lana A, Rodriguez-Artalejo F, Lopez-Garcia E (2015) Dairy consumption and risk of frailty in older adults: a prospective cohort study. J Am Geriatr Soc 63:1852–1860. https://doi.org/10.1111/jgs.13626
doi: 10.1111/jgs.13626
pubmed: 26311353
Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Uchida K, Takasugi S, Kitazono T, Kiyohara Y, Ninomiya T (2019) Dairy consumption and risk of functional disability in an elderly Japanese population: the Hisayama Study. Am J Clin Nutr 109:1664–1671. https://doi.org/10.1093/ajcn/nqz040
doi: 10.1093/ajcn/nqz040
pubmed: 31075788
Rahi B, Pellay H, Chuy V, Helmer C, Samieri C, Féart C (2021) Dairy product intake and long-term risk for frailty among French elderly community dwellers. Nutrients 13:2151. https://doi.org/10.3390/nu13072151
doi: 10.3390/nu13072151
pubmed: 34201489
pmcid: 8308304
Siefkas AC, Millar CL, Dufour AB, Kiel DP, Jacques PF, Hannan MT, Sahni S (2023) Dairy food intake is not associated with frailty in adults from the Framingham Heart Study. J Acad Nutr Diet 123:729-739.e1. https://doi.org/10.1016/j.jand.2022.09.012
doi: 10.1016/j.jand.2022.09.012
pubmed: 36108932
Dobreva I, Marston L, Mukadam N (2022) Which components of the Mediterranean diet are associated with dementia? A UK Biobank cohort study. Geroscience 44:2541–2554. https://doi.org/10.1007/s11357-022-00615-2
doi: 10.1007/s11357-022-00615-2
pubmed: 35794436
pmcid: 9768046
Hockey M, Hoare E, Mohebbi M, Tolmunen T, Hantunen S, Tuomainen TP, Macpherson H, Staudacher H, Jacka FN, Virtanen JK, Rocks T, Ruusunen A (2022) Nonfermented dairy intake, but not fermented dairy intake, associated with a higher risk of depression in middle-age and older Finnish men. J Nutr 152:1916–1926. https://doi.org/10.1093/jn/nxac128
doi: 10.1093/jn/nxac128
pubmed: 35652820
pmcid: 9361734
Ni J, Nishi SK, Babio N, Martínez-González MA, Corella D, Castañer O, Martínez JA, Alonso-Gómez ÁM, Gómez-Gracia E, Vioque J, Romaguera D, López-Miranda J, Estruch R, Tinahones FJ, Lapetra J, Serra-Majem JL, Bueno-Cavanillas A, Tur JA, Martín-Sánchez V, Pintó X, Gaforio JJ, Barabash Bustelo A, Vidal J, Vázquez C, Daimiel L, Ros E, Toledo E, Coltell O, Gómez-Martínez C, Zomeño MD, Donat-Vargas C, Goicolea-Güemez L, Bouzas C, Garcia-de-la-Hera M, Chaplin A, Garcia-Rios A, Casas R, Cornejo-Pareja I, Santos-Lozano JM, Rognoni T, Saiz C, Paz-Graniel I, Malcampo M, Sánchez-Villegas A, Salaverria-Lete I, García-Arellano A, Schröder H, Salas-Salvadó J, PREDIMED-Plus Investigators (2022) Dairy product consumption and changes in cognitive performance: two-year analysis of the PREDIMED-Plus Cohort. Mol Nutr Food Res 66:e2101058. https://doi.org/10.1002/mnfr.202101058
doi: 10.1002/mnfr.202101058
pubmed: 35524484
Vasikaran S, Eastell R, Bruyère O, Foldes AJ, Garnero P, Griesmacher A, McClung M, Morris HA, Silverman S, Trenti T, Wahl DA, Cooper C, Kanis JA, IOF-IFCC Bone Marker Standards Working Group (2011) Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards. Osteoporos Int 22:391–420. https://doi.org/10.1007/s00198-010-1501-1
doi: 10.1007/s00198-010-1501-1
pubmed: 21184054
Heaney RP, Rafferty K, Dowell MS (2002) Effect of yogurt on a urinary marker of bone resorption in postmenopausal women. J Am Diet Assoc 102:1672–1674. https://doi.org/10.1016/s0002-8223(02)90356-1
doi: 10.1016/s0002-8223(02)90356-1
pubmed: 12449294
Johnson JL, Mistry VV, Vukovich MD, Hogie-Lorenzen T, Hollis BW, Specker BL (2005) Bioavailability of vitamin D from fortified process cheese and effects on vitamin D status in the elderly. J Dairy Sci 88:2295–2301. https://doi.org/10.3168/jds.S0022-0302(05)72907-6
doi: 10.3168/jds.S0022-0302(05)72907-6
pubmed: 15956292
Alemán-Mateo H, Macías L, Esparza-Romero J, Astiazaran-García H, Blancas AL (2012) Physiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food. Clin Interv Aging 7:225–234. https://doi.org/10.2147/CIA.S32356
doi: 10.2147/CIA.S32356
pubmed: 22866000
pmcid: 3410682
Alemán-Mateo H, Carreón VR, Macías L, Astiazaran-García H, Gallegos-Aguilar AC, Enríquez JR (2014) Nutrient-rich dairy proteins improve appendicular skeletal muscle mass and physical performance, and attenuate the loss of muscle strength in older men and women subjects: a single-blind randomized clinical trial. Clin Interv Aging 9:1517–1525. https://doi.org/10.2147/CIA.S67449
doi: 10.2147/CIA.S67449
pubmed: 25258523
pmcid: 4172033
Bagheri R, Hooshmand Moghadam B, Candow DG, Elliott BT, Wong A, Ashtary-Larky D, Forbes SC, Rashidlamir A (2022) Effects of Icelandic yogurt consumption and resistance training in healthy untrained older males. Br J Nutr 127:1334–1342. https://doi.org/10.1017/S0007114521002166
doi: 10.1017/S0007114521002166
pubmed: 34121642
Suzuki T, Kojima N, Osuka Y, Tokui Y, Takasugi S, Kawashima A, Yamaji T, Hosoi E, Won CW, Kim H (2019) The effects of mold-fermented cheese on brain-derived neurotrophic factor in community-dwelling older Japanese women with mild cognitive impairment: a randomized, controlled, crossover trial. J Am Med Dir Assoc 20:1509-1514.e2. https://doi.org/10.1016/j.jamda.2019.06.023
doi: 10.1016/j.jamda.2019.06.023
pubmed: 31562049
Lu Y, Matsuyama S, Sugawara Y, Sone T, Tsuji I (2022) Dairy intake and incident functional disability among older Japanese adults: the Ohsaki Cohort 2006 Study. Eur J Nutr 61:2627–2637. https://doi.org/10.1007/s00394-022-02843-w
doi: 10.1007/s00394-022-02843-w
pubmed: 35246747
Scarmeas N, Anastasiou CA, Yannakoulia M (2018) Nutrition and prevention of cognitive impairment. Lancet Neurol 17:1006–1015. https://doi.org/10.1016/S1474-4422(18)30338-7
doi: 10.1016/S1474-4422(18)30338-7
pubmed: 30244829
Tessier AJ, Presse N, Rahme E, Ferland G, Bherer L, Chevalier S (2021) Milk, yogurt, and cheese intake is positively associated with cognitive executive functions in older adults of the Canadian Longitudinal Study on Aging. J Gerontol A Biol Sci Med Sci 76:2223–2231. https://doi.org/10.1093/gerona/glab165
doi: 10.1093/gerona/glab165
pubmed: 34115853
de Goeij LC, van de Rest O, Feskens EJM, de Groot LCPGM, Brouwer-Brolsma EM (2020) Associations between the intake of different types of dairy and cognitive performance in dutch older adults: the B-PROOF study. Nutrients 12:468. https://doi.org/10.3390/nu12020468
doi: 10.3390/nu12020468
pubmed: 32069791
pmcid: 7071379
Rahman A, Sawyer Baker P, Allman RM, Zamrini E (2007) Dietary factors and cognitive impairment in community-dwelling elderly. J Nutr Health Aging 11:49–54
pubmed: 17315080
Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, Wang L, Blesch A, Kim A, Conner JM, Rockenstein E, Chao MV, Koo EH, Geschwind D, Masliah E, Chiba AA, Tuszynski MH (2009) Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer’s disease. Nat Med 15:331–337. https://doi.org/10.1038/nm.1912
doi: 10.1038/nm.1912
pubmed: 19198615
pmcid: 2838375
Iuliano S, Poon S, Robbins J, Bui M, Wang X, De Groot L, Van Loan M, Zadeh AG, Nguyen T, Seeman E (2021) Effect of dietary sources of calcium and protein on hip fractures and falls in older adults in residential care: cluster randomised controlled trial. BMJ 375:n2364. https://doi.org/10.1136/bmj.n2364
doi: 10.1136/bmj.n2364
pubmed: 34670754
pmcid: 8527562
Bonjour JP, Benoit V, Pourchaire O, Rousseau B, Souberbielle JC (2011) Nutritional approach for inhibiting bone resorption in institutionalized elderly women with vitamin D insufficiency and high prevalence of fracture. J Nutr Health Aging 15:404–409. https://doi.org/10.1007/s12603-011-0003-y
doi: 10.1007/s12603-011-0003-y
pubmed: 21528169
Bonjour JP, Benoit V, Payen F, Kraenzlin M (2013) Consumption of yogurts fortified in vitamin D and calcium reduces serum parathyroid hormone and markers of bone resorption: a double-blind randomized controlled trial in institutionalized elderly women. J Clin Endocrinol Metab 98:2915–2921. https://doi.org/10.1210/jc.2013-1274
doi: 10.1210/jc.2013-1274
pubmed: 23653431