Family History of Diabetes and Clinical Characteristics in Children at Diagnosis of Type 1 Diabetes-A Swedish Population-Based Study.


Journal

Diabetes care
ISSN: 1935-5548
Titre abrégé: Diabetes Care
Pays: United States
ID NLM: 7805975

Informations de publication

Date de publication:
20 Sep 2024
Historique:
received: 14 03 2024
accepted: 25 08 2024
medline: 20 9 2024
pubmed: 20 9 2024
entrez: 20 9 2024
Statut: aheadofprint

Résumé

To compare the prevalence of parental diabetes between children with and without type 1 diabetes (T1D), and to compare clinical characteristics at diagnosis of T1D in children with, versus without, a family history of diabetes. Parental diabetes among children with T1D was compared with a general population cohort. Clinical characteristics were compared by family history of diabetes in parents and grandparents of 3,603 children with T1D using relative risk (RR) and ANOVA. Children with T1D more often had parents with type 2 diabetes (T2D) (RR 1.88; P < 0.001) than did children without diabetes. Children with T1D and a family history of T2D were more likely to be overweight or obese (P = 0.002). A family history of T2D and being overweight may contribute to increased risk of T1D.

Identifiants

pubmed: 39302847
pii: 157258
doi: 10.2337/dc24-0534
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Stiftelsen Samariten
Organisme : Skåne County Council's Research and Development Foundation
Organisme : Barndiabetesfonden

Informations de copyright

© 2024 by the American Diabetes Association.

Auteurs

Emma Hedlund (E)

Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Department of Paediatrics, Kristianstad Central Hospital, Kristianstad, Sweden.

Jasaman Tojjar (J)

Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Department of Ophthalmology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.

Lisa Lilja (L)

Department of Paediatrics, Skåne University Hospital, Malmö/Lund, Sweden.

Helena Elding Larsson (H)

Department of Paediatrics, Skåne University Hospital, Malmö/Lund, Sweden.
Department of Clinical Sciences Malmö, Lund University, CRC, Malmö, Sweden.

Gun Forsander (G)

The Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden.
Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.

Johnny Ludvigsson (J)

Crown Princess Victoria Childreńs Hospital, Linköping University Hospital, Linköping, Sweden.
Division of Pediatrics, Department of Biomedical and Clinical Sciences, Medical Faculty, Linköping University, Linköping, Sweden.

Claude Marcus (C)

Department of Clinical Science Intervention and Technology, Division of Paediatrics, Karolinska Institute, Stockholm, Sweden.

Fredrik Norström (F)

Umeå University, Department of Epidemiology and Global Health, Umeå, Sweden.

Martina Persson (M)

Sachs' Children and Youth Hospital, Department of Diabetes and Endocrinology, Stockholm, Sweden.
Department of Clinical Science and Education, Karolinska Institute, Södersjukhuset, Stockholm, Sweden.

Annelie Carlsson (A)

Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Department of Paediatrics, Skåne University Hospital, Malmö/Lund, Sweden.

Classifications MeSH