Antibiotic susceptibility of orofacial infections in Bratislava: a 10-year retrospective study.
Humans
Retrospective Studies
Male
Female
Anti-Bacterial Agents
/ pharmacology
Middle Aged
Adult
Microbial Sensitivity Tests
Drug Resistance, Bacterial
Aged
Metronidazole
/ therapeutic use
Adolescent
Clindamycin
/ therapeutic use
Child
Penicillins
Amoxicillin-Potassium Clavulanate Combination
/ therapeutic use
Mouth Diseases
/ microbiology
Hospitalization
Antibiotic resistance
Odontogenic abscess
Orofacial infections
Journal
Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115
Informations de publication
Date de publication:
21 Sep 2024
21 Sep 2024
Historique:
received:
27
07
2024
accepted:
14
09
2024
medline:
21
9
2024
pubmed:
21
9
2024
entrez:
20
9
2024
Statut:
epublish
Résumé
Aim of this study was to analyse causal microbiological agents and their bacterial resistance in orofacial infections requiring hospital admission. Presented is a 10-year retrospective study of patients hospitalised at a single department in 2014-2023. 744 patients were involved. In the statistical analysis, following data was evaluated: causal microbes and their resistance to Penicillin, Amoxicillin-Clavulanate, Clindamycin and Metronidazole. Most frequent aetiology was odontogenic with causal tooth in socket (n = 468; 62,9%), followed by odontogenic - post extraction (n = 152; 20.4%), jaw fracture (n = 41; 5.5%), sialadenitis n = 31 (4.2%), osteonecrosis n = 22 (3.0%), oncological diagnosis in head and neck (n = 17; 2.3%), unknown (n = 10; 1.3%) and multiple factors (n = 3; 0.4%). 408 patients (54.8%) underwent extraoral abscess revision, 336 patients (45.2%) patients were treated locally without extraoral revision. In odontogenic group with tooth still present, superior CRP (m = 145.8 mg/l; SD = 117.7) and leukocyte values (m = 13.6*10 Orofacial infections in head and neck region are mostly of odontogenic origin with causal tooth still in socket. Causal bacteria show a high antibiotic resistance rate, especially to Clindamycin and Metronidazole. Acquired data will be used to determine guidelines for empirical antibiotic prescription in cases of orofacial infections.
Identifiants
pubmed: 39304566
doi: 10.1007/s00784-024-05937-3
pii: 10.1007/s00784-024-05937-3
doi:
Substances chimiques
Anti-Bacterial Agents
0
Metronidazole
140QMO216E
Clindamycin
3U02EL437C
Penicillins
0
Amoxicillin-Potassium Clavulanate Combination
74469-00-4
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
538Informations de copyright
© 2024. The Author(s).
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