How do filter types of renal replacement therapy affect survival in critically ill patients? Concerns about adsorption of nafamostat mesylate on AN69 membranes.
Adsorption
Continuous renal replacement therapy
Filter membrane
Nafamostat mesylate
Journal
BMC nephrology
ISSN: 1471-2369
Titre abrégé: BMC Nephrol
Pays: England
ID NLM: 100967793
Informations de publication
Date de publication:
20 Sep 2024
20 Sep 2024
Historique:
received:
31
05
2024
accepted:
04
09
2024
medline:
21
9
2024
pubmed:
21
9
2024
entrez:
20
9
2024
Statut:
epublish
Résumé
We are writing to you in response to the article published in BMC Nephrology titled "Dose of nafamostat mesylate during continuous kidney replacement therapy in critically ill patients: a two-centre observational study". The study provided valuable information on the use of nafamostat mesylate (NM) during continuous renal replacement therapy (CRRT) in critically ill patients. We noticed in this study that a higher dose of NM resulted in a decrease in ICU and hospital mortality. However, the underlying mechanism behind this phenomenon remains unclear. We believe exploring this further is warranted.
Identifiants
pubmed: 39304801
doi: 10.1186/s12882-024-03745-1
pii: 10.1186/s12882-024-03745-1
doi:
Substances chimiques
nafamostat
Y25LQ0H97D
Guanidines
0
Benzamidines
0
Membranes, Artificial
0
Types de publication
Journal Article
Letter
Langues
eng
Sous-ensembles de citation
IM
Pagination
314Informations de copyright
© 2024. The Author(s).
Références
Kameda S, et al. Dose of nafamostat mesylate during continuous kidney replacement therapy in critically ill patients: a two-centre observational study. BMC Nephrol. 2024;25(1):69.
doi: 10.1186/s12882-024-03506-0
pubmed: 38408970
pmcid: 10895744
Goto S, et al. Differences in the adsorption of nafamostat mesilate between polyester-polymer alloy and polysulfone membranes. J Artif Organs. 2017;20(2):138–44.
doi: 10.1007/s10047-016-0937-2
pubmed: 27896500
Hirayama T, et al. AN69ST membranes adsorb nafamostat mesylate and affect the management of anticoagulant therapy: a retrospective study. J Intensive Care. 2017;5:46.
doi: 10.1186/s40560-017-0244-x
pubmed: 28729905
pmcid: 5516335
Nakamura Y, et al. Adsorption of Nafamostat Mesilate on AN69ST membranes: a single-Center Retrospective and in Vitro Study. Ther Apher Dial. 2017;21(6):620–7.
doi: 10.1111/1744-9987.12587
pubmed: 28960755
Doi K, et al. Associations of Polyethylenimine-Coated AN69ST membrane in continuous renal replacement therapy with the Intensive Care outcomes: observations from a Claims database from Japan. Blood Purif. 2017;44(3):184–92.
doi: 10.1159/000476052
pubmed: 28609776