Exercise intolerance and oxygen dynamics in nontuberculous mycobacteria with bronchiectasis.
And ventilation
Cardiopulmonary exercise testing
Dyspnea
Pulmonary rehabilitation
Tachypnea
Journal
Respiratory investigation
ISSN: 2212-5353
Titre abrégé: Respir Investig
Pays: Netherlands
ID NLM: 101581124
Informations de publication
Date de publication:
20 Sep 2024
20 Sep 2024
Historique:
received:
01
07
2024
revised:
21
08
2024
accepted:
30
08
2024
medline:
22
9
2024
pubmed:
22
9
2024
entrez:
21
9
2024
Statut:
aheadofprint
Résumé
Nontuberculous mycobacterial pulmonary disease (NTM-PD) patients often have exercise intolerance. Pulmonary rehabilitation (PR) to improve such patients' conditions is often not based on its exercise pathophysiology. We have reported that the oxygen consumption (ΔF Clinical data of NTM-PD patients with exertional dyspnea (n = 29) who underwent incremental exercise testing, chest CT, and echocardiography at the same time were compared with those of control participants (n = 12). In the NTM-PD group, 1) peak V' Exertional oxygen consumption, independent of ventilatory ability, is associated with exercise tolerance and ventilatory efficiency, while being related to tachypnea and bronchiectasis rather than cavitation in NTM-PD patients. These findings may be useful in considering exercise physiology-based PR for NTM-PD patients with exertional dyspnea.
Sections du résumé
BACKGROUND
BACKGROUND
Nontuberculous mycobacterial pulmonary disease (NTM-PD) patients often have exercise intolerance. Pulmonary rehabilitation (PR) to improve such patients' conditions is often not based on its exercise pathophysiology. We have reported that the oxygen consumption (ΔF
METHODS
METHODS
Clinical data of NTM-PD patients with exertional dyspnea (n = 29) who underwent incremental exercise testing, chest CT, and echocardiography at the same time were compared with those of control participants (n = 12).
RESULTS
RESULTS
In the NTM-PD group, 1) peak V'
CONCLUSIONS
CONCLUSIONS
Exertional oxygen consumption, independent of ventilatory ability, is associated with exercise tolerance and ventilatory efficiency, while being related to tachypnea and bronchiectasis rather than cavitation in NTM-PD patients. These findings may be useful in considering exercise physiology-based PR for NTM-PD patients with exertional dyspnea.
Identifiants
pubmed: 39305533
pii: S2212-5345(24)00138-2
doi: 10.1016/j.resinv.2024.08.017
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1058-1063Informations de copyright
Copyright © 2024 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors have no conflicts of interest.