Chronic thromboembolic pulmonary hypertension: the diagnostic assessment.
chronic thromboembolic pulmonary hypertension (CTEPH)
diagnosis
narrative review
pulmonary hypertension
rare disease
Journal
Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388
Informations de publication
Date de publication:
2024
2024
Historique:
received:
27
05
2024
accepted:
28
08
2024
medline:
23
9
2024
pubmed:
23
9
2024
entrez:
23
9
2024
Statut:
epublish
Résumé
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) presents a significant diagnostic challenge due to its complex and often nonspecific clinical manifestations. This review outlines a comprehensive approach to the diagnostic assessment of CTEPH, emphasizing the importance of a high index of suspicion in patients with unexplained dyspnea or persistent symptoms post-acute pulmonary embolism. We discuss the pivotal role of multimodal imaging, including echocardiography, ventilation/perfusion scans, CT pulmonary angiography, and magnetic resonance imaging, in the identification and confirmation of CTEPH. Furthermore, the review highlights the essential function of right heart catheterization in validating the hemodynamic parameters indicative of CTEPH, establishing its definitive diagnosis. Advances in diagnostic technologies and the integration of a multidisciplinary approach are critical for the timely and accurate diagnosis of CTEPH, facilitating early therapeutic intervention and improving patient outcomes. This manuscript aims to equip clinicians with the knowledge and tools necessary for the efficient diagnostic workflow of CTEPH, promoting awareness and understanding of this potentially treatable cause of pulmonary hypertension.
Identifiants
pubmed: 39309600
doi: 10.3389/fcvm.2024.1439402
pmc: PMC11412851
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1439402Informations de copyright
© 2024 Simeone, Maggio, Schirone, Rocco, Sarto, Spadafora, Bernardi, Ambrosio, Forte, Vecchio, Valenti, Sciarretta and Vizza.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.