Cervical length evolution in pregnancy and prediction of preterm delivery.

Cervical length Pregnancy Reference chart Spontaneous preterm delivery

Journal

Archives of gynecology and obstetrics
ISSN: 1432-0711
Titre abrégé: Arch Gynecol Obstet
Pays: Germany
ID NLM: 8710213

Informations de publication

Date de publication:
23 Sep 2024
Historique:
received: 22 11 2023
accepted: 12 09 2024
medline: 23 9 2024
pubmed: 23 9 2024
entrez: 23 9 2024
Statut: aheadofprint

Résumé

To construct reference charts for cervical length (CL) in pregnancy based on longitudinal measurements and to assess the value of measuring cervical length after 24 weeks of gestation. CL was measured transvaginally in singleton pregnancies at 5 to 41 weeks. Pregnancies with more than one measurement were used for creating the CL chart, whereas any measurement after 24 weeks was considered for assessing the correlation of CL with preterm delivery. The dataset consisted of 12,601 pregnancies and 33,899 observations. Gestational age was the main predictor of CL (R Gestational age is the main predictor of CL followed by maternal characteristics and history. CL assessment between 24 and 35 + 6 weeks can enhance our ability to predict spontaneous preterm delivery.

Identifiants

pubmed: 39311998
doi: 10.1007/s00404-024-07745-2
pii: 10.1007/s00404-024-07745-2
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

Perin J, Mulick A, Yeung D et al (2022) Global, regional, and national causes of under-5 mortality in 2000–19: an updated systematic analysis with implications for the sustainable development goals. Lancet Child Adolesc Health 6(2):106–115
doi: 10.1016/S2352-4642(21)00311-4 pubmed: 34800370 pmcid: 8786667
Ohuma E, Moller A-B, Bradley E et al (2023) National, regional, and worldwide estimates of preterm birth in 2020, with trends from 2010: a systematic analysis. Lancet 402(10409):1261–1271
doi: 10.1016/S0140-6736(23)00878-4 pubmed: 37805217
Preterm birth: Fact Sheet. World Health Organization Web site. Published May 2023. https://www.who.int/news-room/fact-sheets/detail/preterm-birth . Accessed Jul 2023
Romero R, Conde-Agudelo A, Da Fonseca E, O’Brien JM, Cetingoz E, Creasy GW, Hassan SS, Nicolaides KH (2018) Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix: a meta-analysis of individual patient data. Am J Obstet Gynecol 218:161–180
doi: 10.1016/j.ajog.2017.11.576 pubmed: 29157866
Owen J, Hankins G, Iams JD, Berghella V, Sheffield JS, Perez-Delboy A, Egerman RS, Wing DA, Tomlinson M, Silver R, Ramin SM, Guzman ER, Gordon M, How HY, Knudtson EJ, Szychowski JM, Cliver S, Hauth JC (2009) Multicenter randomized trial of cerclage for preterm birth prevention in high-risk women with shortened midtrimester cervical length. Am J Obstet Gynecol 201(4):375.e1-375.e8
doi: 10.1016/j.ajog.2009.08.015 pubmed: 19788970
Souka AP, Papamihail M, Pilalis A (2020) Very short cervix in low-risk asymptomatic singleton pregnancies: outcome according to treatment and cervical length at diagnosis. Acta Obstet Gynecol Scand 99:1469–1475
doi: 10.1111/aogs.13881 pubmed: 32333390
Alfirevic Z, Owen J, Carreras Moratonas E, Sharp AN, Szychowski JM, Goya M (2013) Vaginal progesterone, cerclage or cervical pessary for preventing preterm birth in asymptomatic singleton pregnant women with a history of preterm birth and a sonographic short cervix. Ultrasound Obstet Gynecol 41:146–151
doi: 10.1002/uog.12300 pubmed: 22991337
Souka AP, Maritsa VA, Eleftheriades M (2024) Screening vs. no screening for preterm delivery in low-risk singleton pregnancies: comparison by propensity score analysis. Arch Gynecol Obstet 309:133–138
doi: 10.1007/s00404-022-06882-w pubmed: 36580115
Iams JD, Goldenberg RL, Meis PJ et al (1996) The length of the cervix and the risk of spontaneous premature delivery: national institute of child health and human development maternal fetal medicine unit network. N Engl J Med 334:567–572
doi: 10.1056/NEJM199602293340904 pubmed: 8569824
Conde-Agudelo A, Romero R (2015) Predictive accuracy of changes in transvaginal sonographic cervical length over time for preterm birth: a systematic review and metaanalysis. Am J Obstet Gynecol 213(06):789–801
doi: 10.1016/j.ajog.2015.06.015 pubmed: 26070703 pmcid: 4675685
Li Q, Reeves M, Owen J, Keith LG (2015) Precocious cervical ripening as a screening target to predict spontaneous preterm delivery among asymptomatic singleton pregnancies: a systematic review. Am J Obstet Gynecol 212(02):145–156
doi: 10.1016/j.ajog.2014.07.003 pubmed: 25017411
Vaisbuch E, Romero R, Erez O, Kusanovic JP, Mazaki-Tovi S, Gotsch F, Romero V, Ward C, Chaiworapongsa T, Mittal P, Sorokin Y, Hassan SS (2010) Clinical significance of early (< 20 weeks) vs. late (20-24 weeks) detection of sonographic short cervix in asymptomatic women in the mid-trimester. Ultrasound Obstet Gynecol 36(4):471–481
doi: 10.1002/uog.7673 pubmed: 20503224 pmcid: 2937193
To MS, Skentou CA, Royston P, Yu CKH, Nicolaides KH (2006) Prediction of patient-specific risk of early preterm delivery using maternal history and sonographic measurement of cervical length: a population-based prospective study. Ultrasound Obstet Gynecol 27:362–367
doi: 10.1002/uog.2773 pubmed: 16565989
van der Ven AJ, van Os MA, Kazemier BM, Kleinrouweler CE, Verhoeven CJ, de Miranda E, van Wassenaer-Leemhuis AG, Kuiper PN, Porath M, Willekes C, Woiski MD, Sikkema MJ, Roumen FJ, Bossuyt PM, Haak MC, de Groot CJ, Mol BW, Pajkrt E (2015) The capacity of mid-pregnancy cervical length to predict preterm birth in low-risk women: a national cohort study. Acta Obstet Gynecol Scand 94(11):1223–1234
doi: 10.1111/aogs.12721 pubmed: 26234711
Kuusela P, Jacobsson B, Söderlund M, Bejlum C, Almström E, Ladfors L, Hagberg H, Wennerholm UB (2015) Transvaginal sonographic evaluation of cervical length in the second trimester of asymptomatic singleton pregnancies, and the risk of preterm delivery. Acta Obstet Gynecol Scand 94(6):598–607
doi: 10.1111/aogs.12622 pubmed: 25732204
Souka AP, Papastefanou I, Pilalis A, Kassanos D, Papadopoulos G (2019) Implementation of universal screening for preterm delivery by mid-trimester cervical-length measurement. Ultrasound Obstet Gynecol 53(3):396–401
doi: 10.1002/uog.19050 pubmed: 29536576
Papastefanou I, Pilalis A, Eleftheriades M, Souka AP (2015) Prediction of preterm delivery by late cervical length measurement after 24 weeks. Fetal Diagn Ther 38(3):200–204
doi: 10.1159/000381144 pubmed: 26367859
Souka AP, Papastefanou I, Papadopoulos G, Chrelias C, Kassanos D (2015) Cervical length in late second and third trimesters: a mixture model for predicting delivery. Ultrasound Obstet Gynecol 45(3):308–312
doi: 10.1002/uog.13407 pubmed: 24817155
Bortoletto TG, Silva TV, Borovac-Pinheiro A, Pereira CM, Silva AD, França MS, Hatanaka AR, Argenton JP, Passini R Jr, Mol BW, Cecatti JG, Pacagnella RC (2021) Cervical length varies considering different populations and gestational outcomes: results from a systematic review and meta-analysis. PLoS ONE 16(2):e0245746
doi: 10.1371/journal.pone.0245746 pubmed: 33592005 pmcid: 7886126
Berghella V, Roman A, Daskalakis C, Ness A, Baxter JK (2007) Gestational age at cervical length measurement and incidence of preterm birth. Obstet Gynecol 110:311–317
doi: 10.1097/01.AOG.0000270112.05025.1d pubmed: 17666605
Hoesli IM, Strutas D, Tercanli S, Holzgreve W (2003) Charts for cervical length in singleton pregnancy. Int J Gynecol Obstet 82:161–165
doi: 10.1016/S0020-7292(02)00443-5
Salomon LJ, Diaz-Garcia C, Bernard JP et al (2009) Reference range for cervical length throughout pregnancy: non-parametric LMS-based model applied to a large sample. Ultrasound Obstet Gynecol 33:459–464
doi: 10.1002/uog.6332 pubmed: 19277949
Silva SVL, Damiao R, Fonseca EB, Garcia S, Lippi UG (2010) Reference ranges for cervical length by transvaginal scan in singleton pregnancies. J Matern Fetal Neonatal Med 23(5):379–382
doi: 10.3109/14767050903177169 pubmed: 19895354
Papastefanou I, Pilalis A, Kappou D, Souka AP (2016) Cervical length at 11–40 weeks: unconditional and conditional longitudinal reference ranges. Acta Obstet Gynecol Scand 95(12):1376–1382
doi: 10.1111/aogs.13025 pubmed: 27638185
Gudicha DW, Romero R, Kabiri D, Hernandez-Andrade E, Pacora P, Erez O, Kusanovic JP, Jung E, Paredes C, Berry SM, Yeo L, Hassan SS, Hsu C-D, Tarca AL (2021) Personalized assessment of cervical length improves prediction of spontaneous preterm birth: a standard and a percentile calculator. Am J Obstet Gynecol 224(3):288.e1-288.e17
doi: 10.1016/j.ajog.2020.09.002 pubmed: 32918893
Kagan KO, Sonek J (2015) How to measure cervical length. Ultrasound Obstet Gynecol 45:358–362
doi: 10.1002/uog.14742 pubmed: 25632014
Yu K, Lu Z, Stander J (2003) Quantile regression: applications and current research areas. J R Stat Soc Ser D (Stat) 52(3):331–350

Auteurs

A P Souka (AP)

1st Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece. athena.souka@gmail.com.
Fetal-Maternal Medicine Unit, Emvryomitriki Fetal Medicine Unit, Leto Maternity Hospital, 41, D.Soutsou str, 11521, Athens, Greece. athena.souka@gmail.com.

V Maritsa (V)

1st Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Fetal-Maternal Medicine Unit, Emvryomitriki Fetal Medicine Unit, Leto Maternity Hospital, 41, D.Soutsou str, 11521, Athens, Greece.

P Antsaklis (P)

1st Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece.

A Pilalis (A)

Fetal-Maternal Medicine Unit, Emvryomitriki Fetal Medicine Unit, Leto Maternity Hospital, 41, D.Soutsou str, 11521, Athens, Greece.

G Daskalakis (G)

1st Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Classifications MeSH