KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons.


Journal

bioRxiv : the preprint server for biology
ISSN: 2692-8205
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
11 Sep 2024
Historique:
medline: 24 9 2024
pubmed: 24 9 2024
entrez: 24 9 2024
Statut: epublish

Résumé

Mutations in the microtubule binding motor protein, kinesin family member 5A (KIF5A), cause the fatal motor neuron disease, Amyotrophic Lateral Sclerosis. While KIF5 family members transport a variety of cargos along axons, it is still unclear which cargos are affected by

Identifiants

pubmed: 39314491
doi: 10.1101/2024.09.06.611684
pmc: PMC11418931
pii:
doi:

Types de publication

Journal Article Preprint

Langues

eng

Auteurs

Classifications MeSH