Benzenesulfonohydrazide-tethered non-fused and fused heterocycles as potential anti-mycobacterial agents targeting enoyl acyl carrier protein reductase (InhA) with antibiofilm activity.
Journal
RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657
Informations de publication
Date de publication:
18 Sep 2024
18 Sep 2024
Historique:
received:
02
08
2024
accepted:
09
09
2024
medline:
24
9
2024
pubmed:
24
9
2024
entrez:
24
9
2024
Statut:
epublish
Résumé
Because resistant variants of the disease are always emerging, tuberculosis is a global issue that affects economies. New antitubercular medications should be developed, and this can be done by inhibiting druggable targets. Enoyl acyl carrier protein (ACP) reductase (InhA) is a crucial enzyme for the survival of
Identifiants
pubmed: 39315015
doi: 10.1039/d4ra05616g
pii: d4ra05616g
pmc: PMC11418391
doi:
Types de publication
Journal Article
Langues
eng
Pagination
30165-30179Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
No potential conflicts of interest was reported by the author(s).