Predictors of self-care in patients with cancer treated with oral anticancer agents: A systematic review.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2024
Historique:
received: 03 04 2024
accepted: 04 07 2024
medline: 24 9 2024
pubmed: 24 9 2024
entrez: 24 9 2024
Statut: epublish

Résumé

In the last two decades, the use of oral anticancer agents (OAAs) has increased in cancer patients. Despite this, patients and their caregivers face some challenging issues (side effects, drug-to-drug interactions, etc.) related to OAA administration. The three dimensions of self-care by Riegel et al., self-care maintenance (i.e., stability of patient condition), self-care monitoring (i.e., detection of side effects), and self-care management (i.e., management of side effects), may be implemented to avoid negative outcomes. However, knowledge of self-care determinants is necessary to recognise people at risk of poor self-care behaviours. Determine which are the predictors of self-care maintenance, self-care monitoring and self-care management in patients with cancer taking OAA. A systematic review with narrative synthesis was conducted. We included studies on adult patients with cancer using any kind of oral anticancer agent and describing a predictor of self-care. The search was performed on PubMed, CINAHL/PsycINFO, and Web of Science. Of 3,061 records, 45 studies were included in this review. Forty-six predictors organised into 14 categories were identified. In general, all studies focused only on adherence, considered as a self-care maintenance component, and none of them focused on other dimensions of self-care. The predictors of OAA adherence most reported were age, side effects, and socioeconomic factors (e.g., insurance status, and annual income). This systematic review highlighted the literature gap on the analysis of determinants of self-care behaviours in patients taking OAAs. This element could be a starting point for future research that can provide elements to support the oncology nursing research agenda, aimed at recognising patients at risk of poor self-care.

Sections du résumé

BACKGROUND BACKGROUND
In the last two decades, the use of oral anticancer agents (OAAs) has increased in cancer patients. Despite this, patients and their caregivers face some challenging issues (side effects, drug-to-drug interactions, etc.) related to OAA administration. The three dimensions of self-care by Riegel et al., self-care maintenance (i.e., stability of patient condition), self-care monitoring (i.e., detection of side effects), and self-care management (i.e., management of side effects), may be implemented to avoid negative outcomes. However, knowledge of self-care determinants is necessary to recognise people at risk of poor self-care behaviours.
AIMS OBJECTIVE
Determine which are the predictors of self-care maintenance, self-care monitoring and self-care management in patients with cancer taking OAA.
METHODS METHODS
A systematic review with narrative synthesis was conducted. We included studies on adult patients with cancer using any kind of oral anticancer agent and describing a predictor of self-care. The search was performed on PubMed, CINAHL/PsycINFO, and Web of Science.
RESULTS RESULTS
Of 3,061 records, 45 studies were included in this review. Forty-six predictors organised into 14 categories were identified. In general, all studies focused only on adherence, considered as a self-care maintenance component, and none of them focused on other dimensions of self-care. The predictors of OAA adherence most reported were age, side effects, and socioeconomic factors (e.g., insurance status, and annual income).
CONCLUSIONS CONCLUSIONS
This systematic review highlighted the literature gap on the analysis of determinants of self-care behaviours in patients taking OAAs. This element could be a starting point for future research that can provide elements to support the oncology nursing research agenda, aimed at recognising patients at risk of poor self-care.

Identifiants

pubmed: 39316559
doi: 10.1371/journal.pone.0307838
pii: PONE-D-24-13478
doi:

Substances chimiques

Antineoplastic Agents 0

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0307838

Informations de copyright

Copyright: © 2024 Ucciero et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Auteurs

Silvia Ucciero (S)

Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.

Federica Lacarbonara (F)

Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.

Angela Durante (A)

School of Advanced Studies Sant'Anna, Health Science Center, Pisa, Italy.

Francesco Torino (F)

Department of Systems Medicine, Medical Oncology, Tor Vergata University of Rome, Rome, Italy.

Izabella Uchmanowicz (I)

Department of Nursing and Obstetrics, Wroclaw Medical University, Wroclaw, Poland.

Ercole Vellone (E)

Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.

Marco Di Nitto (M)

Department of Health Sciences, University of Genoa, Genoa, Italy.

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Classifications MeSH