ASME V&V40
finite element analysis
in silico
lumbar spinal fusion implant
medical device testing
model credibility
patient-specific
topology optimisation
Journal
Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513
Informations de publication
Date de publication:
2024
2024
Historique:
received:
01
12
2023
accepted:
07
08
2024
medline:
25
9
2024
pubmed:
25
9
2024
entrez:
25
9
2024
Statut:
epublish
Résumé
A full-scale topology optimisation formulation has been developed to automate the design of cages used in instrumented transforaminal lumbar interbody fusion. The method incorporates the mechanical response of the adjacent bone structures in the optimisation process, yielding patient-specific spinal fusion cages that both anatomically and mechanically conform to the patient, effectively mitigating subsidence risk compared to generic, off-the-shelf cages and patient-specific devices. In this study,
Identifiants
pubmed: 39318669
doi: 10.3389/fbioe.2024.1347961
pii: 1347961
pmc: PMC11420557
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1347961Informations de copyright
Copyright © 2024 Smit, Aage, Haschtmann, Ferguson and Helgason.
Déclaration de conflit d'intérêts
The authors declare that they have filed a patent application based on the topology optimization method that is used in this work.