Aldgamycins Q


Journal

The Journal of antibiotics
ISSN: 1881-1469
Titre abrégé: J Antibiot (Tokyo)
Pays: England
ID NLM: 0151115

Informations de publication

Date de publication:
25 Sep 2024
Historique:
received: 22 07 2024
accepted: 13 09 2024
revised: 02 09 2024
medline: 26 9 2024
pubmed: 26 9 2024
entrez: 25 9 2024
Statut: aheadofprint

Résumé

Two novel 16-membered macrolides, named aldgamycin Q

Identifiants

pubmed: 39322834
doi: 10.1038/s41429-024-00775-7
pii: 10.1038/s41429-024-00775-7
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to the Japan Antibiotics Research Association.

Références

Arsic B, et al. 16-membered macrolide antibiotics: a review. Int J Antimicrob Agents. 2018;51:283–98.
doi: 10.1016/j.ijantimicag.2017.05.020 pubmed: 28668674
Karpiński TM. Marine macrolides with antibacterial and/or antifungal activity. Mar Drugs. 2019;17:241.
doi: 10.3390/md17040241 pubmed: 31018512 pmcid: 6520931
Kunstmann MP, Mitscher LA, Patterson EL. Aldgamycin E, a new neutral macrolide antibiotic. Antimicrob Agents Chemother. 1964;10:87–90.
pubmed: 14288037
Achenbach H, Karl W. Metabolites of microorganisms. VIII. Aldgamycin F, in a new antibiotic from Streptomyces lavendulae. Chem Ber 1975;108:780–9.
doi: 10.1002/cber.19751080311
Mizobuchi S, Mochizuki J, Soga H, Tanba H, Inoue H. Aldgamycin G, a new macrolide antibiotic. J Antibiot. 1986;39:1776–8.
doi: 10.7164/antibiotics.39.1776
Zitouni A, Sabaou N, Mathieu F, Lebrihi A. Novel saccharothrix strain and antibiotics derived therefrom, i.e. mutactimycins and aldgamycins. Patent US 20070202574A1. 2007.
Park JS, Yang HO, Kwon HC. Aldgamycin I, an antibacterial 16-membered macrolide from the abandoned mine bacterium, Streptomyces sp. KMA-001. J Antibiot. 2009;62:171–5.
doi: 10.1038/ja.2009.6
Wang CX, et al. Aldgamycins J–O, 16-membered macrolides with a branched octose unit from Streptomycetes sp. and their antibacterial activities. J Nat Prod. 2016;79:2446–54.
doi: 10.1021/acs.jnatprod.6b00200 pubmed: 27690254
Späth G, Fürstner A. Scalable de novo synthesis of aldgarose and total synthesis of aldgamycin N. Angew Chem Int Ed Engl. 2021;133:7979–84.
doi: 10.1002/ange.202016477
Muralikrishna K, Satyanarayana V, Kumar GC, Yadav JS. Studies towards the synthesis of aldgamycin–M. ChemistrySelect. 2019;4:3002–5.
doi: 10.1002/slct.201803591
Wang L, et al. Marcolides from soil-derived Streptomyces sp. KIB-K1 and their antimicrobial activities. Nat Prod Res Dev. 2019;31:1764–71.
Chatterjee S, Reddy GCS, Franco CMM, Rupp RH, Ganguli BN. Swalpamycin, a new macrolide antibiotic II. Structure elucidation. J Antibiot. 1987;40:1368–74.
doi: 10.7164/antibiotics.40.1368
Wang X, Tabudravu J, Jaspars M, Deng H. Tianchimycins A–B, 16-membered macrolides from the rare actinomycete Saccharothrix xinjiangensis. Tetrahedron. 2013;69:6060–4.
doi: 10.1016/j.tet.2013.05.094
Liu S, et al. Bioprospecting of soil-derived actinobacteria along the Alar-Hotan desert highway in the Taklamakan desert. Front Microbiol. 2021;12:604999.
doi: 10.3389/fmicb.2021.604999 pubmed: 33790875 pmcid: 8005632
Woo PWK, Rubin JR. Chalcomycin: single-crystal X-ray crystallographic analysis; biosynthetic and stereochemical correlations with other polyoxo macrolide antibiotics. Tetrahedron. 1996;52:3857–72.
doi: 10.1016/S0040-4020(96)00052-X
Espinel-Ingroff A, Kerkering TM, Goldson PR, Shadomy S. Comparison study of broth macrodilution and microdilution antifungal susceptibility tests. J Clin Microbiol. 1991;29:1089–94.
doi: 10.1128/jcm.29.6.1089-1094.1991 pubmed: 1864923 pmcid: 269950
Dai P, et al. Characterization of methyltransferase AlmCII in chalcomycin biosynthesis: the first TylF family O‐methyltransferase works on a 4′‐deoxysugar. Chembiochem. 2017;18:1510–7.
doi: 10.1002/cbic.201700216 pubmed: 28488816
Bernard SM, et al. Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases. ACS Chem Biol. 2015;10:1340–51.
doi: 10.1021/cb5009348 pubmed: 25692963 pmcid: 4433623

Auteurs

Keke Luo (K)

Department of Microbial Chemistry, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, 100050, Beijing, China.

Qin Yang (Q)

Department of Microbial Chemistry, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, 100050, Beijing, China.

Yuyu Liu (Y)

Department of Microbial Chemistry, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, 100050, Beijing, China.

Chenghang Sun (C)

Department of Microbial Chemistry, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, 100050, Beijing, China. chenghangsun@hotmail.com.

Shaowei Liu (S)

Department of Microbial Chemistry, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, 100050, Beijing, China. liushaowei3535@163.com.

Classifications MeSH