Executive Function and Impulsivity Predict Distinct Genetic Variance in Internalizing Problems, Externalizing Problems, Thought Disorders, and Compulsive Disorders: A Genomic Structural Equation Modeling Study.

Barratt Impulsiveness Scale UPPS-P Impulsive Behavior Scale executive control genomic SEM

Journal

Clinical psychological science : a journal of the Association for Psychological Science
ISSN: 2167-7026
Titre abrégé: Clin Psychol Sci
Pays: United States
ID NLM: 101601751

Informations de publication

Date de publication:
Sep 2024
Historique:
medline: 26 9 2024
pubmed: 26 9 2024
entrez: 26 9 2024
Statut: ppublish

Résumé

Individual differences in self-control predict many health and life outcomes. Building on twin literature, we used genomic structural equation modeling to test the hypothesis that genetic influences on executive function and impulsivity predict independent variance in mental health and other outcomes. The impulsivity factor (comprising urgency, lack of premeditation, and other facets) was only modestly genetically correlated with low executive function (

Identifiants

pubmed: 39323941
doi: 10.1177/21677026231207845
pmc: PMC11423426
doi:

Types de publication

Journal Article

Langues

eng

Pagination

865-881

Déclaration de conflit d'intérêts

Conflict of Interest P.F and S.L.E. are employed by and hold stock or stock options in 23andMe, Inc. The other authors report no conflict of interest.

Auteurs

Daniel E Gustavson (DE)

Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO.

Claire L Morrison (CL)

Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO.
Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO.

Travis T Mallard (TT)

Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
Department of Psychiatry, Harvard Medical School, Boston, MA.

Mariela V Jennings (MV)

Department of Psychiatry, University of California San Diego, La Jolla CA, USA.

Pierre Fontanillas (P)

23andMe Inc., Sunnyvale, California, USA.

Sarah L Elson (SL)

23andMe Inc., Sunnyvale, California, USA.

Abraham A Palmer (AA)

Department of Psychiatry, University of California San Diego, La Jolla CA, USA.
Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.

Naomi P Friedman (NP)

Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO.
Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO.

Sandra Sanchez-Roige (S)

Department of Psychiatry, University of California San Diego, La Jolla CA, USA.
Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.

Classifications MeSH