Rational Design of Dual-Domain Binding Inhibitors for

Journal

JACS Au
ISSN: 2691-3704
Titre abrégé: JACS Au
Pays: United States
ID NLM: 101775714

Informations de publication

Date de publication:
23 Sep 2024
Historique:
received: 15 07 2024
revised: 16 08 2024
accepted: 04 09 2024
medline: 27 9 2024
pubmed: 27 9 2024
entrez: 27 9 2024
Statut: epublish

Résumé

The GalNAc-transferase (GalNAc-T) family, consisting of 20 isoenzymes, regulates the

Identifiants

DOI: 10.1021/jacsau.4c00633 PMID: 39328774 PMC: PMC11423303
pubmed: 39328774
doi: 10.1021/jacsau.4c00633
pmc: PMC11423303
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3649-3656

Informations de copyright

© 2024 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

Auteurs

Ismael Compañón (I)

Department of Chemistry and Instituto de Investigación en Química de la Universidad de La Rioja, Universidad de La Rioja, Logroño 26006, Spain.

Collin J Ballard (CJ)

Department of Biochemistry, Case Western Reserve University, 2109 Adelbert Rd, Cleveland, Ohio 44106, United States.
ORCID: 0000-0003-2869-6970

Erandi Lira-Navarrete (E)

Department of Cellular and Molecular Medicine, Faculty of Health Sciences, Copenhagen Center for Glycomics, University of Copenhagen, Copenhagen 2200, Denmark.

Tanausú Santos (T)

Department of Chemistry and Instituto de Investigación en Química de la Universidad de La Rioja, Universidad de La Rioja, Logroño 26006, Spain.

Serena Monaco (S)

School of Pharmacy, University of East Anglia, Norwich Research Park, NR4 7TJ Norwich, U.K.
ORCID: 0000-0001-9396-7568

Juan C Muñoz-García (JC)

School of Pharmacy, University of East Anglia, Norwich Research Park, NR4 7TJ Norwich, U.K.
Instituto de Investigaciones Químicas, Consejo Superior de Investigaciones Científicas and Universidad de Sevilla, Avenida Américo Vespucio, 49, Sevilla 41092, Spain.
ORCID: 0000-0003-2246-3236

Ignacio Delso (I)

School of Pharmacy, University of East Anglia, Norwich Research Park, NR4 7TJ Norwich, U.K.

Jesus Angulo (J)

School of Pharmacy, University of East Anglia, Norwich Research Park, NR4 7TJ Norwich, U.K.
Instituto de Investigaciones Químicas, Consejo Superior de Investigaciones Científicas and Universidad de Sevilla, Avenida Américo Vespucio, 49, Sevilla 41092, Spain.
ORCID: 0000-0001-7250-5639

Thomas A Gerken (TA)

Department of Biochemistry, Case Western Reserve University, 2109 Adelbert Rd, Cleveland, Ohio 44106, United States.
Departments of Biochemistry and Chemistry, Case Western Reserve University, 2109 Adelbert Rd, Cleveland, Ohio 44106, United States.

Katrine T Schjoldager (KT)

Department of Cellular and Molecular Medicine, Faculty of Health Sciences, Copenhagen Center for Glycomics, University of Copenhagen, Copenhagen 2200, Denmark.

Henrik Clausen (H)

Department of Cellular and Molecular Medicine, Faculty of Health Sciences, Copenhagen Center for Glycomics, University of Copenhagen, Copenhagen 2200, Denmark.

Tomás Tejero (T)

Department of Organic Chemistry, Faculty of Sciences, University of Zaragoza, Zaragoza 50009, Spain.
Institute of Chemical Synthesis and Homogeneous Catalysis, University of Zaragoza-CSIC, Zaragoza 50009, Spain.
ORCID: 0000-0003-3433-6701

Pedro Merino (P)

Department of Organic Chemistry, Faculty of Sciences, University of Zaragoza, Zaragoza 50009, Spain.
Institute for Biocomputation and Physics of Complex Systems, University of Zaragoza, Zaragoza 50018, Spain.
ORCID: 0000-0002-2202-3460

Francisco Corzana (F)

Department of Chemistry and Instituto de Investigación en Química de la Universidad de La Rioja, Universidad de La Rioja, Logroño 26006, Spain.
ORCID: 0000-0001-5597-8127

Ramon Hurtado-Guerrero (R)

Department of Cellular and Molecular Medicine, Faculty of Health Sciences, Copenhagen Center for Glycomics, University of Copenhagen, Copenhagen 2200, Denmark.
Institute for Biocomputation and Physics of Complex Systems, University of Zaragoza, Zaragoza 50018, Spain.
Fundación ARAID, Zaragoza 50018, Spain.
ORCID: 0000-0002-3122-9401

Mattia Ghirardello (M)

Department of Chemistry and Instituto de Investigación en Química de la Universidad de La Rioja, Universidad de La Rioja, Logroño 26006, Spain.
ORCID: 0000-0002-2855-4801

Classifications MeSH