In Vivo Efficacy of Rezafungin, Anidulafungin, Caspofungin, and Micafungin against Four

Candida auris echinocandins murine model

Journal

Journal of fungi (Basel, Switzerland)
ISSN: 2309-608X
Titre abrégé: J Fungi (Basel)
Pays: Switzerland
ID NLM: 101671827

Informations de publication

Date de publication:
29 Aug 2024
Historique:
received: 25 07 2024
revised: 20 08 2024
accepted: 26 08 2024
medline: 27 9 2024
pubmed: 27 9 2024
entrez: 27 9 2024
Statut: epublish

Résumé

Rezafungin is the first new drug approved to treat candidaemia and invasive candidiasis in more than 10 years. However, data are scant on the in vivo efficacy of rezafungin and the other three approved echinocandins against different This study involved 10 isolates representing 4 Regardless of isolate and clade, all echinocandin regimens improved survival after 21 days ( Regardless of the

Identifiants

DOI: 10.3390/jof10090617 PMID: 39330378
pubmed: 39330378
pii: jof10090617
doi: 10.3390/jof10090617
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : National Research, Development and Innovation Office
ID : FK138462
Organisme : Hungarian Academy of Sciences
ID : BO/00127/21/8
Organisme : National Research, Development and Innovation Fund
ID : UNKP-23-5-DE-480
Organisme : National Research, Development and Innovation Fund
ID : UNKP-23-4-II-DE-73

Auteurs

Dávid Balázsi (D)

Medical Microbiology, Clinical Center, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Doctoral School of Pharmaceutical Sciences, University of Debrecen, 4032 Debrecen, Hungary.

Zoltán Tóth (Z)

Medical Microbiology, Clinical Center, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.

Jeffrey B Locke (JB)

Cidara Therapeutics, Inc., 6310 Nancy Ridge Dr., Suite 101, San Diego, CA 92121, USA.
ORCID: 0000-0001-8145-0828

Andrew M Borman (AM)

UK National Mycology Reference Laboratory, UK Health Security Agency, Science Quarter, Southmead Hospital, Bristol BS10 5NB, UK.
Medical Research Council Centre for Medical Mycology (MRC CMM), University of Exeter, Exeter EX4 4QD, UK.
ORCID: 0000-0003-0585-5721

Lajos Forgács (L)

Medical Microbiology, Clinical Center, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Doctoral School of Pharmaceutical Sciences, University of Debrecen, 4032 Debrecen, Hungary.

Noémi Balla (N)

Medical Microbiology, Clinical Center, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Doctoral School of Pharmaceutical Sciences, University of Debrecen, 4032 Debrecen, Hungary.

Fruzsina Kovács (F)

Medical Microbiology, Clinical Center, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Doctoral School of Pharmaceutical Sciences, University of Debrecen, 4032 Debrecen, Hungary.

Renátó Kovács (R)

Medical Microbiology, Clinical Center, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Department of Medical Microbiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
ORCID: 0000-0003-3946-2424

Chiaki Amano (C)

Medical Microbiology, Clinical Center, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.

Tugba Ilay Baran (TI)

Medical Microbiology, Clinical Center, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.

László Majoros (L)

Medical Microbiology, Clinical Center, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Department of Medical Microbiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.

Classifications MeSH