Paving the Way to Innovative, Child-Friendly Pediatric Diagnostic Methods for Tuberculosis: Introduction of Stool-Based Testing in Ukraine.

Ukraine Xpert MTB/RIF Ultra diagnostic algorithm fecal sample/stool pediatric TB tuberculosis

Journal

Tropical medicine and infectious disease
ISSN: 2414-6366
Titre abrégé: Trop Med Infect Dis
Pays: Switzerland
ID NLM: 101709042

Informations de publication

Date de publication:
11 Sep 2024
Historique:
received: 23 07 2024
revised: 28 08 2024
accepted: 29 08 2024
medline: 27 9 2024
pubmed: 27 9 2024
entrez: 27 9 2024
Statut: epublish

Résumé

Like many countries, Ukraine faces challenges with diagnosing tuberculosis (TB) in children due to the paucibacillary nature of the disease and difficulty obtaining respiratory samples. To improve diagnostic efficiency, stool testing is being integrated into routine pediatric TB services. This started with a pilot introduction at 12 regional TB facilities, where stool was collected for children with a preliminary diagnosis of TB, based on clinical and/or radiological or laboratory findings, in addition to routine testing. For 168 children, a stool test was conducted between November 2021 and September 2022, with samples submitted in all 12 pilot regions. For 132 children, other samples were available in addition to stool.

Identifiants

pubmed: 39330898
pii: tropicalmed9090209
doi: 10.3390/tropicalmed9090209
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : USAID
ID : 72012119CA00002

Auteurs

Olena Diuzheva (O)

PATH, 25B, Shota Rustaveli St., 01033 Kyiv, Ukraine.

Liudmyla Skoklyuk (L)

PATH, 25B, Shota Rustaveli St., 01033 Kyiv, Ukraine.

Nina Zherebko (N)

PATH, 25B, Shota Rustaveli St., 01033 Kyiv, Ukraine.

Anna Barbova (A)

Central Reference Laboratory for Microbiological Diagnostics of Tuberculosis of the Ministry of Health of Ukraine, 10 Amosova St, 03038 Kyiv, Ukraine.

Myroslava Germanovych (M)

PATH, 25B, Shota Rustaveli St., 01033 Kyiv, Ukraine.

Eveline Klinkenberg (E)

PATH, 25B, Shota Rustaveli St., 01033 Kyiv, Ukraine.

Oleksii Bogdanov (O)

PATH, 25B, Shota Rustaveli St., 01033 Kyiv, Ukraine.

Gunta Dravniece (G)

PATH, 25B, Shota Rustaveli St., 01033 Kyiv, Ukraine.

Classifications MeSH