Partial prostatectomy for localized prostate cancer.
Erectile dysfunction
Partial prostatectomy
Prostate cancer
Systematic review
Urinary incontinence
Journal
World journal of urology
ISSN: 1433-8726
Titre abrégé: World J Urol
Pays: Germany
ID NLM: 8307716
Informations de publication
Date de publication:
27 Sep 2024
27 Sep 2024
Historique:
received:
14
06
2024
accepted:
27
08
2024
medline:
27
9
2024
pubmed:
27
9
2024
entrez:
27
9
2024
Statut:
epublish
Résumé
Localized prostate cancer treatment aims to balance cancer control with preserving urinary and erectile function. While focal ablative therapies have emerged, their uncertain prognosis prompts exploration of partial prostatectomy. We systematically reviewed its efficacy as a primary treatment, particularly in low-to-intermediate-risk patients. Our review comprehensively analyzed existing studies on partial prostatectomy for localized cancer. We focused on patient selection, surgical techniques, and postoperative outcomes, emphasizing tumor control, continence, and erectile function. Studies involving multiparametric MRI and targeted biopsies for candidate selection were included. Partial prostatectomy, encompassing various techniques, demonstrates promising short-term outcomes in tumor control and functional preservation. Preoperative imaging and biopsy aid in candidate selection. However, longer-term data on cancer recurrence are limited, warranting further investigation. Heterogeneity among studies and the lack of standardized follow-up protocols are notable limitations. Partial prostatectomy offers a minimally invasive and effective treatment option for localized prostate cancer, particularly in selected patients. Preoperative imaging and biopsy play crucial roles in patient selection, while standardized follow-up protocols are needed to assess long-term outcomes. Future research should focus on elucidating its precise role and optimizing patient selection criteria, contributing to improved prostate cancer management strategies. Partial prostatectomy is explored for localized prostate cancer treatment, aiming to balance cancer control with preserving function. Short-term outcomes are promising, but long-term data on recurrence are lacking. Further research is needed to optimize patient selection and standardize follow-up protocols.
Sections du résumé
BACKGROUND AND OBJECTIVE
OBJECTIVE
Localized prostate cancer treatment aims to balance cancer control with preserving urinary and erectile function. While focal ablative therapies have emerged, their uncertain prognosis prompts exploration of partial prostatectomy. We systematically reviewed its efficacy as a primary treatment, particularly in low-to-intermediate-risk patients.
METHODS
METHODS
Our review comprehensively analyzed existing studies on partial prostatectomy for localized cancer. We focused on patient selection, surgical techniques, and postoperative outcomes, emphasizing tumor control, continence, and erectile function. Studies involving multiparametric MRI and targeted biopsies for candidate selection were included.
KEY FINDINGS AND LIMITATIONS
UNASSIGNED
Partial prostatectomy, encompassing various techniques, demonstrates promising short-term outcomes in tumor control and functional preservation. Preoperative imaging and biopsy aid in candidate selection. However, longer-term data on cancer recurrence are limited, warranting further investigation. Heterogeneity among studies and the lack of standardized follow-up protocols are notable limitations.
CONCLUSIONS AND CLINICAL IMPLICATIONS
CONCLUSIONS
Partial prostatectomy offers a minimally invasive and effective treatment option for localized prostate cancer, particularly in selected patients. Preoperative imaging and biopsy play crucial roles in patient selection, while standardized follow-up protocols are needed to assess long-term outcomes. Future research should focus on elucidating its precise role and optimizing patient selection criteria, contributing to improved prostate cancer management strategies.
ADVANCING PRACTICE
UNASSIGNED
Partial prostatectomy is explored for localized prostate cancer treatment, aiming to balance cancer control with preserving function. Short-term outcomes are promising, but long-term data on recurrence are lacking. Further research is needed to optimize patient selection and standardize follow-up protocols.
Identifiants
pubmed: 39331129
doi: 10.1007/s00345-024-05242-4
pii: 10.1007/s00345-024-05242-4
doi:
Types de publication
Journal Article
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
543Subventions
Organisme : Natural Science Foundation of Shenzhen City
ID : No. JCYJ20210324141404010
Organisme : Key Research and Development Program of Hubei Province
ID : 2023DJC160
Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
Sung HA-O et al Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. (1542–4863 (Electronic))
Williams IS et al Modern paradigms for prostate cancer detection and management. (1326–5377 (Electronic))
Fletcher SA et al Contemporary national trends in prostate cancer risk profile at diagnosis. (1476–5608 (Electronic))
Bill-Axelson A et al Radical Prostatectomy or Watchful Waiting in Prostate Cancer – 29-Year Follow-up. (1533–4406 (Electronic))
Capogrosso P et al Are We Improving Erectile Function Recovery After Radical Prostatectomy? Analysis of Patients Treated over the Last Decade. (1873–7560 (Electronic))
Woodcock DA-OX et al Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy. (2041 – 1723 (Electronic))
Fujihara AA-O, Ukimura OA-O. Focal Therapy Localized Prostate cancer. Int J Urol. 2022 Nov;29(11):1254-1263.
Abreu AL et al High Intensity Focused Ultrasound Hemigland Ablation for Prostate Cancer: Initial Outcomes of a United States Series. (1527–3792 (Electronic))
Frasson M et al Rectal cancer threatening or affecting the prostatic plane: is partial prostatectomy oncologically adequate? Results of a multicentre retrospective study. (1463 – 1318 (Electronic))
Murakami K et al. A case of partial prostatectomy for advanced rectal Cancer involving the prostate in the Jack-Knife position. Hinyokika Kiyo. 2015 Sep;61(9):365-8.
Wunderlich H et al (2006) Radical cystectomy with ultrasound-guided partial prostatectomy for bladder cancer: a complication-preventing concept. Urology 68(3):554–559
doi: 10.1016/j.urology.2006.03.047
pubmed: 16979737
Sivaraman A, Barret E. Focal Therapy Prostate Cancer: À La Carte Approach. Eur Urol. 2016 Jun;69(6):973-5.
Villers A et al (2017) Partial prostatectomy for Anterior Cancer: short-term oncologic and functional outcomes. Eur Urol 72(3):333–342
doi: 10.1016/j.eururo.2016.08.057
pubmed: 27613061
Villers A et al (2017) Robot-assisted partial prostatectomy for anterior prostate cancer: a step-by-step guide. BJU Int 119(6):968–974
doi: 10.1111/bju.13785
pubmed: 28111893
pmcid: 9084536
Villers A et al (2023) Robot partial prostatectomy for Anterior Cancer: long-term functional and oncological outcomes at 7 years. Eur Urol Open Sci 55:11–14
doi: 10.1016/j.euros.2023.07.001
pubmed: 37521072
pmcid: 10374895
Ficarra V et al Systematic review and meta-analysis of studies reporting urinary continence recovery after robot-assisted radical prostatectomy. (1873–7560 (Electronic))
Barocas DA et al Association Between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes After 3 Years. (1538–3598 (Electronic))
Donovan Jl Fau -, Hamdy FC et al Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer. (1533–4406 (Electronic))
Guo CC et al The relationship of TMPRSS2-ERG gene fusion between primary and metastatic prostate cancers. (1532–8392 (Electronic))
Guillaumier S et al. A Multicentre Study of 5-year outcomes following focal therapy in treating clinically. Signif Nonmetastatic Prostate Cancer. Eur Urol. 2018 Oct;74(4):422-429.
Bass R et al Oncologic and Functional Outcomes of Partial Gland Ablation with High Intensity Focused Ultrasound for Localized Prostate Cancer. (1527–3792 (Electronic))
Bratan F et al How accurate is multiparametric MR imaging in evaluation of prostate cancer volume? (1527 – 1315 (Electronic))
Cooper CS et al. Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue. Nat Genet. 2015 Apr;47(4):367-372.
Sood A et al (2019) The Precision Prostatectomy: an IDEAL stage 0, 1 and 2a study. BMJ Surg Interv Health Technol 1(1):e000002
doi: 10.1136/bmjsit-2019-000002
pubmed: 35047770
pmcid: 8647607
Sood A et al (2022) Description of Surgical technique and oncologic and functional outcomes of the Precision Prostatectomy Procedure (IDEAL Stage 1-2b study). Eur Urol 81(4):396–406
doi: 10.1016/j.eururo.2021.10.017
pubmed: 34872786
Kasivisvanathan V, Emberton M, Moore CM MRI-Targeted Biopsy for Prostate-Cancer Diagnosis. (1533–4406 (Electronic))
Ahmed HF, Berge V et al Corrigendum: Can we deliver randomized trials of focal therapy in prostate cancer? LID – 10.1038/nrclinonc.2017.86 [doi]. (1759–4782 (Electronic))
Valerio M et al. Detection of clinically significant prostate Cancer using magnetic resonance imaging-Ultrasound Fusion targeted biopsy: a systematic review. Eur Urol. 2015 Jul;68(1):8-19.
Kaouk J et al Single Port Transvesical Robotic Radical Prostatectomy: Initial Clinical Experience and Description of Technique. (1527–9995 (Electronic))
Kaouk JH, Sagalovich D, Garisto J (2018) Robot-assisted transvesical partial prostatectomy using a purpose-built single-port robotic system. BJU Int 122(3):520–524
doi: 10.1111/bju.14194
pubmed: 29533505
Kaouk JH et al (2022) Single-port robotic transvesical partial prostatectomy for localized prostate Cancer: initial series and description of technique. Eur Urol 82(5):551–558
doi: 10.1016/j.eururo.2022.07.017
pubmed: 35970657
Bianco FJ Jr., J.A. Scardino Pt Fau - Eastham, and, Eastham JA Radical prostatectomy: long-term cancer control and recovery of sexual and urinary function (trifecta). (1527–9995 (Electronic))
Prabhu V et al Long-term continence outcomes in men undergoing radical prostatectomy for clinically localized prostate cancer. (1873–7560 (Electronic))
Heesakkers J et al Pathophysiology and Contributing Factors in Postprostatectomy Incontinence: A Review. (1873–7560 (Electronic))
Asimakopoulos AD et al. Bladder neck preservation during minimally invasive radical prostatectomy: a standardised technique using a lateral approach. BJU Int. 2012 Nov;110(10):1566-71.
Porpiglia F et al Total Anatomical Reconstruction During Robot-assisted Radical Prostatectomy: Implications on Early Recovery of Urinary Continence. (1873–7560 (Electronic))
Daouacher G, Waldén M A simple reconstruction of the posterior aspect of rhabdosphincter and sparing of puboprostatic collar reduces the time to early continence after laparoscopic radical prostatectomy. J Endourol. 2014 Apr;28(4):481-6.
Asimakopoulos AD et al. Retzius-sparing versus standard robot-assisted radical prostatectomy: a prospective randomized comparison on immediate continence rates. Surg Endosc. 2019 Jul;33(7):2187-2196.
van Randenborgh H et al (2004) Improved urinary continence after radical retropubic prostatectomy with preparation of a long, partially intraprostatic portion of the membraneous urethra: an analysis of 1013 consecutive cases. Prostate Cancer Prostatic Dis 7(3):253–257
doi: 10.1038/sj.pcan.4500726
pubmed: 15184863
Schlomm T et al (2011) Full functional-length urethral sphincter preservation during radical prostatectomy. Eur Urol 60(2):320–329
doi: 10.1016/j.eururo.2011.02.040
pubmed: 21458913
Sfoungaristos S, Kontogiannis S, Perimenis P (2013) Early continence recovery after preservation of maximal urethral length until the level of verumontanum during radical prostatectomy: primary oncological and functional outcomes after 1 year of follow-up. Biomed Res Int 2013:426208
doi: 10.1155/2013/426208
pubmed: 24163815
pmcid: 3791568
Hamada A et al (2014) Early return of continence in patients undergoing robot-assisted laparoscopic prostatectomy using modified maximal urethral length preservation technique. J Endourol 28(8):930–938
doi: 10.1089/end.2013.0794
pubmed: 24739066
Heo JE et al (1932) Urethral realignment with maximal urethral length and bladder neck preservation in robot-assisted radical prostatectomy: Urinary continence recovery. –6203 (Electronic))
Wiatr T et al. Long-term functional outcomes of vesicourethral anastomosis with bladder neck preservation and distal urethral length preservation after videolaparoscopic radical prostatectomy. Wideochir Inne Tech Maloinwazyjne. 2022 Sep; 17(3): 540–547.
Nunez Bragayrac LA et al (2020) Feasibility and continence outcomes of extended prostatic urethral preservation during robot-assisted radical prostatectomy. Prostate Cancer Prostatic Dis 23(2):286–294
doi: 10.1038/s41391-019-0173-y
pubmed: 31700145
Asimakopoulos AA-OX et al. Urethral-Sparing Robotic Radical Prostatectomy: Crit Appraisal Saf Technique Based Histologic Characteristics Prostatic Urethra. Curr Oncol. 2023 Jan 12;30(1):1065-1076.
Hugosson J et al Mortality results from the Göteborg randomised population-based prostate-cancer screening trial. (1474–5488 (Electronic)).
Iczkowski KA et al Preoperative prediction of unifocal, unilateral, margin-negative, and small volume prostate cancer. (1527–9995 (Electronic))
Musunuru HB et al Active Surveillance for Intermediate Risk Prostate Cancer: Survival Outcomes in the Sunnybrook Experience. (1527–3792 (Electronic))
Sharma V et al Cost-Effectiveness of Active Surveillance, Radical Prostatectomy and External Beam Radiotherapy for Localized Prostate Cancer: An Analysis of the ProtecT Trial. (1527–3792 (Electronic))
Abdul-Muhsin HM et al (2017) Natural orifice transluminal endoscopic partial prostatectomy: a real-time image-guided focal extirpative feasibility study. Urology 107:262–266
doi: 10.1016/j.urology.2017.05.024
pubmed: 28551173
Tosoian JJ et al Intermediate and Longer-Term Outcomes From a Prospective Active-Surveillance Program for Favorable-Risk Prostate Cancer. (1527–7755 (Electronic))
Sundi D et al Very-high-risk localized prostate cancer: definition and outcomes. (1476–5608 (Electronic))
Serrano Na Fau -, Anscher MS, Anscher MS Favorable vs Unfavorable Intermediate-Risk Prostate Cancer: A Review of the New Classification System and Its Impact on Treatment Recommendations. (0890–9091 (Print))
Ball MA-O et al. Pathological analysis of the prostatic anterior fat pad at radical prostatectomy: insights from a prospective series. BJU Int. 2017 Mar;119(3):444-448.
Connor MJ et al. Prostate Imaging and Focal Therapy. Transl Androl Urol. 2020 Jun;9(3):1479-1480.
Oishi M et al Hemigland Cryoablation of Localized Low, Intermediate and High Risk Prostate Cancer: Oncologic and Functional Outcomes at 5 Years. (1527–3792 (Electronic))
Kongnyuy M et al PSA kinetics following primary focal cryotherapy (hemiablation) in organ-confined prostate cancer patients. (1433–8726 (Electronic))
Shoji SA-O et al. Focal therapy with high-intensity focused ultrasound for the localized prostate cancer for Asian based on the localization with MRI-TRUS fusion image-guided transperineal biopsy and 12-cores transperineal systematic biopsy: prospective analysis of oncological and functional outcomes. Int J Clin Oncol. 2020 Oct;25(10):1844-1853.
Al HA, Awamlh B et al. Prostate Multiparametric Magn Reson Imaging Features Following Partial Gland Cryoablation. Urology. 2020 Apr:138:98-105.