A Qualitative Exploration of Women With Cystic Fibrosis and Urinary Incontinence.
Journal
Urogynecology (Philadelphia, Pa.)
ISSN: 2771-1897
Titre abrégé: Urogynecology (Phila)
Pays: United States
ID NLM: 9918452588006676
Informations de publication
Date de publication:
19 Sep 2024
19 Sep 2024
Historique:
medline:
27
9
2024
pubmed:
27
9
2024
entrez:
27
9
2024
Statut:
aheadofprint
Résumé
Women with cystic fibrosis (CF) historically experience a high prevalence of urinary incontinence (UI). However, this area is understudied, especially in the modern era of highly effective modulator therapy (HEMT). This study aimed to explore the UI experiences, knowledge, care-seeking behavior, and treatment preferences of women with CF. We recruited women aged ≥18 years through the CF Foundation's Community Voice national registry if they had a diagnosis of CF and reported UI. Participants underwent individual, semistructured interviews exploring their experiences, attitudes, and preferences toward UI that were audiorecorded and transcribed. Two coders performed thematic analysis using deductive and inductive coding approaches. Twenty-six participants completed interviews (average age, 45.1 years; range, 24-61 years). Key themes included the following: (1) most women with CF and UI report low bother from symptoms likely related to stress UI, and HEMT has greatly improved UI symptoms and decreased bother; (2) most women with CF and UI had previously discussed UI symptoms with family and/or peers but had not sought care due to stigma or low priority; (3) women with CF and UI had minimal knowledge about UI in general and how it relates to CF; (4) most desired broad screening for UI from their CF team and improved multidisciplinary care; and (5) highly effective UI treatment options with low-time commitment and easily accessible resources are desired. Women with CF and UI report low knowledge and care-seeking behavior related to this condition and desire improved care provision. Importantly, HEMT may improve UI symptoms among people with CF.
Identifiants
pubmed: 39331807
doi: 10.1097/SPV.0000000000001572
pii: 02273501-990000000-00266
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 American Urogynecologic Society. All rights reserved.
Déclaration de conflit d'intérêts
Megan Bradley reports grant funding from Axonics. The remaining authors report no conflict of interest.
Références
Haylen BT, de Ridder D, Freeman RM, et al. An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction. Int Urogynecol J. 2010;21(1):5–26. doi:10.1007/s00192-009-0976-9.
doi: 10.1007/s00192-009-0976-9
Buckley BS, Lapitan MC; Epidemiology Committee of the Fourth International Consultation on incontinence, Paris, 2008. Prevalence of urinary incontinence in men, women, and children—current evidence: findings of the fourth international consultation on incontinence. Urology. 2010;76(2):265–270. doi:10.1016/j.urology.2009.11.078.
doi: 10.1016/j.urology.2009.11.078
Markland AD, Vaughan CP, Okosun IS, et al. Cluster analysis of multiple chronic conditions associated with urinary incontinence among women in the USA. BJU Int. 2018;122(6):1041–1048. doi:10.1111/bju.14246.
doi: 10.1111/bju.14246
Izci Y, Topsever P, Filiz TM, et al. The association between diabetes mellitus and urinary incontinence in adult women. Int Urogynecol J Pelvic Floor Dysfunct. 2009;20(8):947–952. doi:10.1007/s00192-009-0888-8.
doi: 10.1007/s00192-009-0888-8
Yang C, Feng Z, Chen Z, et al. The risk factors for urinary incontinence in female adults with chronic cough. BMC Pulm Med. 2022;22(1):276. doi:10.1186/s12890-022-02069-w.
doi: 10.1186/s12890-022-02069-w
Cystic Fibrosis Foundation. 2022 Patient registry annual data report. Annual Data Report. 2023.
Caverly LJ, Riquelme SA, Hisert KB. The impact of highly effective modulator therapy on cystic fibrosis microbiology and inflammation. Clin Chest Med. 2022;43(4):647–665. doi:10.1016/j.ccm.2022.06.007.
doi: 10.1016/j.ccm.2022.06.007
Kazmerski TM, Prushinskaya OV, Hill K, et al. Sexual and reproductive health of young women with cystic fibrosis: a concept mapping study. Acad Pediatr. 2019;19(3):307–314. doi:10.1016/j.acap.2018.08.011.
doi: 10.1016/j.acap.2018.08.011
Frayman KB, Kazmerski TM, Sawyer SM. A systematic review of the prevalence and impact of urinary incontinence in cystic fibrosis. Respirology. 2018;23(1):46–54. doi:10.1111/resp.13125.
doi: 10.1111/resp.13125
Vella M, Cartwright R, Cardozo L, et al. Prevalence of incontinence and incontinence-specific quality of life impairment in women with cystic fibrosis. Neurourol Urodyn. 2009;28(8):986–989. doi:10.1002/nau.20732.
doi: 10.1002/nau.20732
Reichman G, De Boe V, Braeckman J, et al. Urinary incontinence in patients with cystic fibrosis. Scand J Urol. 2016;50(2):128–131. doi:10.3109/21681805.2015.1096826.
doi: 10.3109/21681805.2015.1096826
O’Halloran T, Bell RJ, Robinson PJ, et al. Urinary incontinence in young nulligravid women: a cross-sectional analysis. Ann Intern Med. 2012;157(2):87–93. doi:10.7326/0003-4819-157-2-201207170-00005.
doi: 10.7326/0003-4819-157-2-201207170-00005
Kazmerski TM, Stransky OM, Lavage DR, et al. Sexual and reproductive health experiences and care of adult women with cystic fibrosis. J Cyst Fibros. 2023;22(2):223–233. doi:10.1016/j.jcf.2022.09.013.
doi: 10.1016/j.jcf.2022.09.013
Kazmerski TM, Gmelin T, Slocum B, et al. Attitudes and decision making related to pregnancy among young women with cystic fibrosis. Matern Child Health J. 2017;21(4):818–824. doi:10.1007/s10995-016-2181-z.
doi: 10.1007/s10995-016-2181-z
Hubeaux K, Gueganton L, Nowak E, et al. Prevalence and severity of functional urinary and anorectal disorders and their impact on quality of life in cystic fibrosis. J Cyst Fibros October. 2024;23(3):579–586. doi:10.1016/j.jcf.2023.10.011.
doi: 10.1016/j.jcf.2023.10.011
Wan X, Wang C, Xu D, et al. Disease stigma and its mediating effect on the relationship between symptom severity and quality of life among community-dwelling women with stress urinary incontinence: a study from a Chinese city. J Clin Nurs. 2014;23(15–16):2170–2179. doi:10.1111/jocn.12482.
doi: 10.1111/jocn.12482
Rodríguez-Almagro J, Hernández Martínez A, Martínez-Vázquez S, et al. A qualitative exploration of the perceptions of women living with pelvic floor disorders and factors related to quality of life. J Clin Med. 2024;13(7):1896. doi:10.3390/jcm13071896.
doi: 10.3390/jcm13071896
Jouanny C, Abhyankar P, Maxwell M. A mixed methods systematic literature review of barriers and facilitators to help-seeking among women with stigmatised pelvic health symptoms. BMC Womens Health. 2024;24(1):217. doi:10.1186/s12905-024-03063-6.
doi: 10.1186/s12905-024-03063-6
Nixon GM, Glazner JA, Martin JM, et al. Urinary incontinence in female adolescents with cystic fibrosis. Pediatrics. 2002;110(2 Pt 1):e22. doi:10.1542/peds.110.2.e22.
doi: 10.1542/peds.110.2.e22
Cornacchia M, Zenorini A, Perobelli S, et al. Prevalence of urinary incontinence in women with cystic fibrosis. BJU Int. 2001;88(1):44–48. doi:10.1046/j.1464-410x.2001.02242.x.
doi: 10.1046/j.1464-410x.2001.02242.x