Imaging features of hepatic angiosarcoma: retrospective analysis of two centers.
Humans
Hemangiosarcoma
/ diagnostic imaging
Liver Neoplasms
/ diagnostic imaging
Male
Female
Retrospective Studies
Middle Aged
Aged
Positron Emission Tomography Computed Tomography
/ methods
Tomography, X-Ray Computed
/ methods
Magnetic Resonance Imaging
/ methods
Ultrasonography
/ methods
Adult
Contrast Media
Liver
/ diagnostic imaging
Angiosarcoma
Computed tomography enhancement
Contrast-enhanced ultrasound
Liver tumor
Positron emission tomography-computed tomography
Journal
BMC cancer
ISSN: 1471-2407
Titre abrégé: BMC Cancer
Pays: England
ID NLM: 100967800
Informations de publication
Date de publication:
27 Sep 2024
27 Sep 2024
Historique:
received:
09
03
2024
accepted:
16
08
2024
medline:
28
9
2024
pubmed:
28
9
2024
entrez:
28
9
2024
Statut:
epublish
Résumé
Identifying primary hepatic angiosarcoma (PHA) preoperatively is challenging, often relying on postoperative pathology. Invasive biopsy increases bleeding risk, emphasizing the importance of early PHA diagnosis through imaging. However, comprehensive summaries of ultrasound, abdominal computed tomography (CT), magnetic resonance imaging (MRI), and whole- body positron emission tomography-CT (PET-CT) in this context are lacking. This study aimed to investigate the comprehensive imaging characteristics of PHA. Imaging data were collected from 7 patients diagnosed with PHA via pathology between January 2000 and December 2019 in two provincial grade III hospitals. All patients underwent routine color ultrasound examinations before surgery, with 3 patients receiving contrast-enhanced ultrasound (CEUS).CT scans, both plain and enhanced, were performed on 5 patients, and whole-body PET-CT examinations were conducted on 2 patients. Among the 7 patients with PHA, 4 presented with a single solid intrahepatic mass (2 of which were large), 1 with a single exophytic macroblock type, 1 with a mixed type featuring multiple masses and nodules, and 1 with a multiple nodule type. Conventional ultrasound of PHA showed uneven echoes within the tumor, potentially accompanied by septal zone echoes, and a blood flow grade of 0-I. CEUS displayed early-stage circular high enhancement, a central non-enhancement area, and a "vascular sign" around the tumor. CT scans revealed low-density shadows in the plain scan stage, high peripheral ring enhancement, and punctate nodular enhancement in the arterial phase, with varying intensities and the presence of a "vascular sign." During the portal vein stage, the interior of the tumor was consistently unfilled and exhibited structural disorder. PET-CT showed low-density lesions in the liver and low fluorodeoxyglucose metabolism. Imaging diagnosis plays a crucial role in PHA diagnosis. When liver tumor imaging matches the above characteristics, consider PHA.
Identifiants
pubmed: 39333917
doi: 10.1186/s12885-024-12817-2
pii: 10.1186/s12885-024-12817-2
doi:
Substances chimiques
Contrast Media
0
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1191Subventions
Organisme : Fujian Provincial Science and Technology Plan Guiding Project Fund
ID : 2022Y0013
Organisme : High-Level Medical Care Construction Foundation Of Fujian Province
ID : [2021]76
Informations de copyright
© 2024. The Author(s).
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