Complex trauma sequelae: Mycobacterium goodii and Priestia endophytica Hardware infection in a patient with Ehlers-Danlos syndrome.
Mycobacterium goodii
Priestia endophytica
Ehlers-Danlos Syndrome
Post-traumatic hardware infections
Journal
BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551
Informations de publication
Date de publication:
27 Sep 2024
27 Sep 2024
Historique:
received:
28
06
2024
accepted:
20
09
2024
medline:
28
9
2024
pubmed:
28
9
2024
entrez:
28
9
2024
Statut:
epublish
Résumé
A 26-year-old man with Ehlers-Danlos syndrome, recurrent otitis externa, and chronic otitis media sustained a left lower extremity amputation and open femur fracture with internal hardware fixation after a motor vehicle collision in Arizona. He presented to the emergency department at our institution with severe left leg pain and purulent discharge despite receiving two unidentified antibiotics upon discharge. Evaluations revealed an abscess and malunion of the femur. Initial cultures yielded scant Priestia endophytica, leading to daptomycin treatment. His condition worsened until Gram-positive bacilli identified as Mycobacterium goodii, a rare nosocomial mycobacterial species, were found. Significant improvement occurred with appropriate antibiotics. This case highlights the challenges in diagnosing and managing M. goodii infections in immunocompromised patients with orthopedic complications and notes P. endophytica as a previously unreported, possibly opportunistic human pathogen.
Identifiants
pubmed: 39333951
doi: 10.1186/s12879-024-09970-1
pii: 10.1186/s12879-024-09970-1
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1064Informations de copyright
© 2024. The Author(s).
Références
Malfait F, De Paepe A. The Ehlers-Danlos syndrome. Adv Exp Med Biol. 2014;802:129–43.
doi: 10.1007/978-94-007-7893-1_9
pubmed: 24443025
Byers PH, Belmont J, Black J, De Backer J, Frank M, Jeunemaitre X, et al. Diagnosis, natural history, and management in vascular Ehlers-Danlos syndrome. Am J Med Genet C Semin Med Genet. 2017;175:40–7.
doi: 10.1002/ajmg.c.31553
pubmed: 28306228
National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Care Services; Committee on Selected Heritable Disorders of Connective Tissue and Disability. Selected heritable disorders of connective tissue and disability. Washington (DC): National Academies Press (US); 2022.
Gupta RS, Patel S, Saini N, Chen S. Robust demarcation of 17 distinct Bacillus species clades, proposed as novel Bacillaceae genera, by phylogenomics and comparative genomic analyses: description of Robertmurraya kyonggiensis sp. nov. and proposal for an emended genus Bacillus limiting it only to the members of the subtilis and Cereus clades of species. Int J Syst Evol Microbiol. 2020;70:5753–98.
doi: 10.1099/ijsem.0.004475
pubmed: 33112222
Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley C, Gordin F, et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007;175:367–416.
doi: 10.1164/rccm.200604-571ST
pubmed: 17277290
Reva ON, Smirnov VV, Pettersson B, Priest FG. Bacillus endophyticus sp. nov., isolated from the inner tissues of cotton plants (Gossypium Sp). Int J Syst Evol Microbiol. 2002;52:101–7.
doi: 10.1099/00207713-52-1-101
pubmed: 11837291
Bakhtiyarifar M, Enayatizamir N, Mehdi Khanlou K. Biochemical and molecular investigation of non-rhizobial endophytic bacteria as potential biofertilisers. Arch Microbiol. 2021;203:513–21.
doi: 10.1007/s00203-020-02038-z
pubmed: 32965526
Hussein W, Ramadan WA, Ibrahim HF. Isolation and identification of associated endophytic bacteria from barely seeds harbour non-ribosomal peptides and enhance tolerance to salinity stress. Beni-Suef Univ J Basic Appl Sci. 2024;13:27.
doi: 10.1186/s43088-024-00483-z
Brenner DJ, Krieg NR, Staley JT, Garrity GM, Boone DR, De Vos P, et al. editors. Bergey’s manual
Lekota KE, Bezuidt OKI, Mafofo J, Rees J, Muchadeyi FC, Madoroba E, et al. Whole genome sequencing and identification of Bacillus endophyticus and B. Anthracis isolated from anthrax outbreaks in South Africa. BMC Microbiol. 2018;18:67.
doi: 10.1186/s12866-018-1205-9
pubmed: 29986655
pmcid: 6038202
Brown BA, Springer B, Steingrube VA, Wilson RW, Pfyffer GE, Garcia MJ, et al. Mycobacterium wolinskyi sp. nov. and Mycobacterium goodii sp. nov., two new rapidly growing species related to Mycobacterium smegmatis and associated with human wound infections: a cooperative study from the International Working Group on Mycobacterial Taxonomy. Int J Syst Bacteriol. 1999;49:1493–511.
doi: 10.1099/00207713-49-4-1493
pubmed: 10555330
Mohajeri P, Yazdani L, Shahraki AH, Alvandi A, Atashi S, Farahani A, et al. Verification of frequency in species of Nontuberculous Mycobacteria in Kermanshah drinking Water supplies using the PCR-Sequencing method. Microb Drug Resist. 2017;23:359–64.
doi: 10.1089/mdr.2016.0064
pubmed: 27668545
Diaz A, Ardura MI, Wang H, Antonara S, Ouellette CP. Osteomyelitis due to Mycobacterium goodii in an adolescent, United States. Emerg Infect Dis. 2020;26:2781–3.
doi: 10.3201/eid2611.200206
pubmed: 33079043
pmcid: 7588509
Sohail MR, Smilack JD. Hernia repair mesh-associated Mycobacterium goodii infection. J Clin Microbiol. 2004;42:2858–60.
doi: 10.1128/JCM.42.6.2858-2860.2004
pubmed: 15184492
pmcid: 427896
Ahmad S, Khakoo RA. Left knee prosthesis-related Mycobacterium goodii infection. Int J Infect Dis. 2010;14:e1115–6.
doi: 10.1016/j.ijid.2010.02.2245
pubmed: 21071255
Hollingshead C, Ali SS, Hubbard N. Mycobacterium goodii infection associated with bilateral breast tissue expanders. BMJ Case Rep. 2024;17.
Miklovic T, Sieg VC. Ehlers-Danlos Syndrome. StatPearls. Treasure Island. (FL): StatPearls Publishing; 2024.
Islam M, Chang C, Gershwin ME. Ehlers-Danlos Syndrome: immunologic contrasts and connective tissue comparisons. J Transl Autoimmun. 2021;4:100077.
doi: 10.1016/j.jtauto.2020.100077
pubmed: 33437956